Clinical trial · Interventional
Whether it is More Appropriate to Spray Lugol's Solution From Cervical Esophagus to Esophagogastric Junction
NCT04224363CI-TRIAL-00042749unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to compare the effectiveness and safety of spraying Lugol's solution from cervical esophagus to esophagogastric junction (downward) and from esophagogastric junction to cervical esophagus （upward）during chromoendoscopy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| staining from cervical esophagus to esophagogastric junction | Procedure | — | UNRESOLVED |
| staining from esophagogastric junction to cervical esophagus | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Downward Staining
- description
- This group patients were given Lugol's solution staining from cervical esophagus to esophagogastric junction （downward）during chromemdoscopy.
- interventionNames
- Procedure: staining from cervical esophagus to esophagogastric junction
- type
- EXPERIMENTAL
- label
- Upward Staining
- description
- This group patients were given Lugol's solution staining from esophagogastric junction to cervical esophagus（upward）during chromemdoscopy.
- interventionNames
- Procedure: staining from esophagogastric junction to cervical esophagus
Primary outcomes (1)
- measure
- Image Quality
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * High risk patients of early esophageal squamous neoplasias. Exclusion Criteria: * After esophageal surgery or endoscopic treatment ; * Known esophageal radiotherapy or chemotherapy ; * Esophageal stenosis; * Acute bleeding; * A known allergy to iodine; * Coagulopathy (prothrombin time \<50% of control, partial thromboplastin time \>50 seconds); * Having food retention; * Severe hepatic ,renal, cardiovascular or metabolic dysfunction ; * Being pregnant or lactating.
References
Publications (0)
Data not yet available
No reference posted for this study.