Cancer Family
Endocrine Neoplasm
CI-CAN-00000015Explore in graph →
Non-malignant764 active trials16 approved drugs64 evidence items
- NCIt
- C3010
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Cancer Family
CI-CAN-00000015Explore in graph →
Genomics
20 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
496 cases with simple somatic mutation data · 515 cases total · 2026-01-14 · mapped to Thyroid Gland Papillary Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | BRAF | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 293 |
| 496 |
| 59.1% |
| cbioportal |
| 2 | NRAS | Ssm | 39 | 496 | 7.9% | cbioportal |
| 3 | TG | Ssm | 19 | 496 | 3.8% | cbioportal |
| 4 | HRAS | Ssm | 17 | 496 | 3.4% | cbioportal |
| 5 | TTN | Ssm | 16 | 496 | 3.2% | cbioportal |
| 8 | MUC16 | Ssm | 7 | 496 | 1.4% | cbioportal |
| 9 | SPTA1 | Ssm | 7 | 496 | 1.4% | cbioportal |
| 10 | ZFHX3 | Ssm | 7 | 496 | 1.4% | cbioportal |
| 6 | EIF1AX | Ssm | 7 | 496 | 1.4% | cbioportal |
| 7 | KMT2A | Ssm | 7 | 496 | 1.4% | cbioportal |
| 11 | BDP1 | Ssm | 6 | 496 | 1.2% | cbioportal |
| 12 | USP9X | Ssm | 6 | 496 | 1.2% | cbioportal |
| 19 | RYR1 | Ssm | 5 | 496 | 1% | cbioportal |
| 16 | PCDH11X | Ssm | 5 | 496 | 1% | cbioportal |
| 13 | AKT1 | Ssm | 5 | 496 | 1% | cbioportal |
| 18 | PTPRZ1 | Ssm | 5 | 496 | 1% | cbioportal |
| 15 | GBF1 | Ssm | 5 | 496 | 1% | cbioportal |
| 17 | PDZD2 | Ssm | 5 | 496 | 1% | cbioportal |
| 14 | ATM | Ssm | 5 | 496 | 1% | cbioportal |
| 21 | ARFGEF2 | Ssm | 4 | 496 | 0.8% | cbioportal |
| 28 | HMCN1 | Ssm | 4 | 496 | 0.8% | cbioportal |
| 27 | GRIN2B | Ssm | 4 | 496 | 0.8% | cbioportal |
| 22 | ARID2 | Ssm | 4 | 496 | 0.8% | cbioportal |
| 25 | CHEK2 | Ssm | 4 | 496 | 0.8% | cbioportal |
| 26 | CSMD2 | Ssm | 4 | 496 | 0.8% | cbioportal |
| 24 | BSN | Ssm | 4 | 496 | 0.8% | cbioportal |
| 23 | BPTF | Ssm | 4 | 496 | 0.8% | cbioportal |
| 42 | PPM1D | Ssm | 4 | 496 | 0.8% | cbioportal |
| 41 | PLEC | Ssm | 4 | 496 | 0.8% | cbioportal |
| 40 | PKHD1 | Ssm | 4 | 496 | 0.8% | cbioportal |
Data updated 21 days agoSource updated 2026-01-14