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CancerIndexthe global index of cancer

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

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CancerIndex

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Digestive System Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Digestive System Neoplasm

Cancer Family

Digestive System Neoplasm

CI-CAN-00000012Explore in graph →

Non-malignant4,733 active trials43 approved drugs557 evidence items

NCIt: C3052
MeSH: D004067
MeSH: D005770

Overview
Statistics
Survival
Genomics102
Variants & evidence557
Drugs121
Trials22059
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (1,073)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 926–950 of 1,073 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

mTOR inhibitor treatment of pancreatic cancer in a patient With Peutz-Jeghers syndrome.
· J Clin Oncol · 2011 · PMID 21189378 · validated civic_curation pubmed
Response to angiotensin blockade with irbesartan in a patient with metastatic colorectal cancer.
· Ann Oncol · 2016 · PMID 27022066 · validated civic_curation pubmed
Identification of a novel metabolic-related mutation (IDH1) in metastatic pancreatic cancer.
· Cancer Biol Ther · 2018 · PMID 27466707 · validated civic_curation pubmed
Phase I study of pazopanib and vorinostat: a therapeutic approach for inhibiting mutant p53-mediated angiogenesis and facilitating mutant p53 degradation.
· Ann Oncol · 2015 · PMID 25669829 · validated civic_curation pubmed
A Rare EGFR-SEPT14 Fusion in a Patient with Colorectal Adenocarcinoma Responding to Erlotinib.
· Oncologist · 2020 · PMID 32162810 · validated civic_curation pubmed
Gastroblastoma mimics the embryonic mesenchyme of the foregut: a case report.
· Diagn Pathol · 2023 · PMID 36803776 · validated civic_curation pubmed
Gastroblastoma in old age.
· Histopathology · 2019 · PMID 31287169 · validated civic_curation pubmed
KDR Mutation as a Novel Predictive Biomarker of Exceptional Response to Regorafenib in Metastatic Colorectal Cancer.

Showing 926–950 of 1,073 publications

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· Cureus · 2016 · PMID 27004155 · validated civic_curation pubmed

Somatic aberrations of mismatch repair genes as a cause of microsatellite-unstable cancers.

· J Pathol · 2014 · PMID 25111426 · validated civic_curation pubmed

Genomic characterization of a well-differentiated grade 3 pancreatic neuroendocrine tumor.

· Cold Spring Harb Mol Case Stud · 2019 · PMID 31160355 · validated civic_curation pubmed

Molecular characterisation of pancreatic ductal adenocarcinoma with NTRK fusions and review of the literature.

· J Clin Pathol · 2023 · PMID 34583947 · validated civic_curation pubmed

NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls.

· Mod Pathol · 2020 · PMID 31375766 · validated civic_curation pubmed

TumorFusions: an integrative resource for cancer-associated transcript fusions.

· Nucleic Acids Res · 2018 · PMID 29099951 · validated civic_curation pubmed

Cyclin D2, but not cyclin D1, overexpression closely correlates with gastric cancer progression and prognosis.

· J Pathol · 1999 · PMID 10547574 · validated civic_curation pubmed

A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.

· Cancer Res · 2013 · PMID 23539443 · validated civic_curation pubmed

Upregulation of the antiapoptotic factor Livin contributes to cisplatin resistance in colon cancer cells.

· Tumour Biol · 2013 · PMID 23188704 · validated civic_curation pubmed

Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab.

· Sci Transl Med · 2011 · PMID 21900593 · validated civic_curation pubmed

Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab.

· Mol Cancer · 2014 · PMID 24894453 · validated civic_curation pubmed

Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines.

· Cell Cycle · 2014 · PMID 24841718 · validated civic_curation pubmed

RAF suppression synergizes with MEK inhibition in KRAS mutant cancer cells.

· Cell Rep · 2014 · PMID 25199829 · validated civic_curation pubmed

Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.

· Cell Rep · 2014 · PMID 24685132 · validated civic_curation pubmed

Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.

· Cancer Cell · 2016 · PMID 26725216 · validated civic_curation pubmed

HER2 activating mutations are targets for colorectal cancer treatment.

· Cancer Discov · 2015 · PMID 26243863 · validated civic_curation pubmed

Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials.

· Mol Cancer Ther · 2014 · PMID 24608574 · validated civic_curation pubmed

Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma.

· Oncotarget · 2016 · PMID 26701727 · validated civic_curation pubmed