Subtype
Digestive System Carcinoma
CI-CAN-00000812Explore in graph →
2,124 active trials27 approved drugs139 evidence items
- NCIt
- C96963
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Subtype
CI-CAN-00000812Explore in graph →
Clinical trials
7,545 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (885)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07479264 | A Study on Intratumoral Fibrosis and α-SMA Expression in Intrahepatic Cholangiocarcinoma | completed | — | 169 | First Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 1 | Mar 18, 2026 | clinicaltrials |
| NCT01165346 | Stereotaxic Irradiation of Hepatocellular Carcinoma(CKNO-HEP) | completed | Phase 2 | 44 | Centre Oscar LambretOTHER | 1 | Mar 13, 2026 |
| clinicaltrials |
| NCT03151213 | Effect of Pregabalin on the Postoperative Analgesia in RFA of Focal Lesions in the Liver(pregabalin) | completed | Phase 4 | 70 | Sherief Abd-ElsalamOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT04301778 | Durvalumab and SNDX-6532 Following Chemo or Radio-Embolization for Patients With Intrahepatic Cholangiocarcinoma | completed | Phase 2 | 5 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT06381648 | Detecting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma (LyMIC)(LyMIC) | completed | — | 230 | City of Hope Medical CenterOTHER | 2 | Mar 13, 2026 | clinicaltrials |
| NCT07224737 | Liquid Biopsy Using Exosomal miRNA Enables Risk Stratification of Potential Metastasis in Patients With Intrahepatic Cholangiocarcinoma.(EXOMIC) | completed | — | 230 | City of Hope Medical CenterOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT07225452 | An Exosomal miRNA-based Liquid Biopsy for ICC Detection(LUMIC) | completed | — | 535 | City of Hope Medical CenterOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT07193316 | Safety and Efficacy of Atezolizumab-Bevacizumab Versus Tyrosin Kinase Inhibitors in Patients With Liver Cirrhosis(SEEK) | completed | — | 38 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 12, 2026 | clinicaltrials |
| NCT05665348 | Study Evaluating the Benefit of Adding Ipilimumab to the Combination of Atezolizumab and Bevacizumab in Patients With Hepatocellular Carcinoma Receiving First-line Systemic Therapy(TRIPLET) | completed | Phase 2 / Phase 3 | 229 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Mar 9, 2026 | clinicaltrials |
| NCT02047474 | Combination Chemotherapy Before and After Surgery in Treating Patients With Localized Pancreatic Cancer | completed | Phase 2 | 46 | Yale UniversityOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT03322267 | Adjuvant Pembrolizumab for Patients With Locally Advanced Esophageal Squamous Cell Carcinoma at High Risk of Recurrence | completed | Phase 2 | 26 | National Taiwan University HospitalOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT04705818 | Combining Epigenetic And Immune Therapy to Beat Cancer.(CAIRE) | completed | Phase 2 | 164 | Institut BergoniéOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT06184867 | Choices About Genetic Testing And Learning Your Risk With Smart Technology(CATALYST) | completed | N/A | 50 | Rutgers, The State University of New JerseyOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT07453433 | Submucosal Pressure Ejection Endoscopic Dissection for Early Gastric Cancer: a Retrospective Cohort Study | completed | — | 548 | Shanghai East HospitalOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT05432492 | A Study of AK112 in Patients With Unresectable Hepatocellular Carcinoma (HCC) | completed | Phase 2 | 40 | AkesoINDUSTRY | 1 | Mar 4, 2026 | clinicaltrials |
| NCT07449065 | CECT Features of MVI Predict Response to TACE Plus TKI in Intermediate-stage HCC | completed | — | 324 | First Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 1 | Mar 4, 2026 | clinicaltrials |
| NCT03686488 | TAS 102 in Combination With Ramucirumab in Advanced, Refractory Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma | completed | Phase 2 | 23 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Mar 2, 2026 | clinicaltrials |
| NCT04238715 | A Study of E7090 in Participants With Unresectable Advanced or Metastatic Cholangiocarcinoma With Fibroblast Growth Factor Receptor (FGFR) 2 Gene Fusion | completed | Phase 2 | 63 | Eisai Co., Ltd.INDUSTRY | 2 | Mar 2, 2026 | clinicaltrials |
| NCT02738359 | Efficacy of Colonoscopy, Colon Capsule and Fecal Immunological Test for Colorectal Cancer Screening(FAMCAP) | completed | — | 84 | Hôpital Edouard HerriotOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT04526106 | REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors | completed | Phase 1 / Phase 2 | 490 | Elevar TherapeuticsINDUSTRY | 13 | Feb 27, 2026 | clinicaltrials |
| NCT04945720 | Hepatic Artery Infusion Chemotherapy (HAIC) Plus Durvalumab for Advanced Hepatocellular Carcinoma | completed | Phase 2 | 30 | Sun Yat-sen UniversityOTHER | 1 | Feb 25, 2026 | clinicaltrials |
| NCT04233567 | Infigratinib for the Treatment of Advanced or Metastatic Solid Tumors in Patients With FGFR Gene Mutations | completed | Phase 2 | 17 | Sameek RoychowdhuryOTHER | 1 | Feb 24, 2026 | clinicaltrials |
| NCT04469556 | Pancreatic Adenocarcinoma Signature Stratification for Treatment(PASS-01) | completed | Phase 2 | 150 | University Health Network, TorontoOTHER | 2 | Feb 20, 2026 | clinicaltrials |
| NCT01858025 | Concurrent Chemoradiation + 5-FU + Mitomycin-C in Anal Carcinoma | completed | Early Phase 1 | 25 | Massachusetts General HospitalOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT02021422 | A Pilot, Prospective, Non-randomized Evaluation of the Safety of Anakinra Plus Standard Chemotherapy | completed | Phase 1 | 13 | Baylor Research InstituteOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT07407257 | SBRT for Liver Tumors, Liver Metastases, and Pancreatic Tumors | completed | N/A | 65 | Institute of Oncology LjubljanaOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT07416825 | Inter-Observer Delineation Differences in Esophageal Cancer GTV on MR, CT, and PET/CT Protokol šečerov Ermenc 28dec19 | completed | N/A | 23 | Institute of Oncology LjubljanaOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT07418138 | Effect of Pre-Transplant Tyrosine Kinase Inhibitors in Hepatocellular Carcinoma Patients With Liver Transplantation | completed | — | 484 | Hu LiangshuoOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT02073994 | Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation | completed | Phase 1 | 174 | Institut de Recherches Internationales ServierOTHER | 2 | Feb 17, 2026 | clinicaltrials |
| NCT03463876 | A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With Apatinib in Patients With Advanced HCC(RESCUE) | completed | Phase 2 | 190 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Feb 17, 2026 | clinicaltrials |
| NCT04418401 | Study on the Safety and Efficacy of Donafinib Combined With Anti-PD-1 Antibody as Adjuvant Therapy for HCC Patients(CISLD-8) | completed | Phase 1 | 30 | Zhejiang UniversityOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT04288323 | Gadolinium Contrast-enhanced Abbreviated MRI (AMRI) vs. Standard Ultrasound for Hepatocellular Carcinoma (HCC) Surveillance in Patients With Cirrhosis | completed | Phase 4 | 79 | University of California, San DiegoOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT07404566 | Utility of MicroRNAs for Diagnosing Hepatocellular Carcinoma in Hepatitis C Patients | completed | — | 84 | Benha UniversityOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT03365882 | S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery | completed | Phase 2 | 240 | SWOG Cancer Research NetworkNETWORK | 2 | Feb 10, 2026 | clinicaltrials |
| NCT04109924 | TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study | completed | Phase 2 | 42 | Roswell Park Cancer InstituteOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT03693807 | A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma | completed | Phase 2 | 35 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT03211416 | Sorafenib Tosylate and Pembrolizumab in Treating Patients With Advanced or Metastatic Liver Cancer | completed | Phase 1 / Phase 2 | 37 | Roswell Park Cancer InstituteOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT03713593 | Safety and Efficacy of Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) Versus Lenvatinib as First-line Therapy in Participants With Advanced Hepatocellular Carcinoma (MK-7902-002/E7080-G000-311/LEAP-002) | completed | Phase 3 | 794 | Merck Sharp & Dohme LLCINDUSTRY | 21 | Feb 5, 2026 | clinicaltrials |
| NCT05142709 | Real-world Experience of ICIs Plus Chemotherapy for Advanced ESCC. | completed | — | 1,197 | Fudan UniversityOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT07386639 | Sex-Specific Machine Learning Models to Predict Distant Metastasis in Liver Cancer(GENDER-HCC-MET) | completed | — | 19,019 | Tongji UniversityOTHER | 0 | Feb 4, 2026 | clinicaltrials |
| NCT03008278 | Olaparib and Ramucirumab in Treating Patients With Metastatic or Locally Recurrent Gastric or Gastroesophageal Junction Cancer That Cannot Be Removed by Surgery | completed | Phase 1 / Phase 2 | 51 | National Cancer Institute (NCI)NIH | 1 | Feb 3, 2026 | clinicaltrials |
| NCT06310590 | Safety and Efficacy of TareSphere in Patients With Unresectable Hepatocellular Carcinoma | completed | Phase 1 | 40 | Chengdu New Radiomedicine Technology Co. LTD.INDUSTRY | 1 | Feb 3, 2026 | clinicaltrials |
| NCT03092895 | A Study of SHR-1210 in Combination With Apatinib or Chemotherapy in Subjects With Advanced PLC or BTC | completed | Phase 2 | 157 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Jan 29, 2026 | clinicaltrials |
| NCT01730937 | Sorafenib Tosylate With or Without Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer | completed | Phase 3 | 193 | Radiation Therapy Oncology GroupNETWORK | 5 | Jan 28, 2026 | clinicaltrials |
| NCT04362839 | Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer | completed | Phase 1 | 39 | City of Hope Medical CenterOTHER | 1 | Jan 28, 2026 | clinicaltrials |
| NCT03264404 | Azacitidine and Pembrolizumab in Pancreatic Cancer | completed | Phase 2 | 36 | Susan E. BatesOTHER | 1 | Jan 27, 2026 | clinicaltrials |
| NCT04640480 | Dose-finding Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SNB-101(SN-38) in Patients With Tumors | completed | Phase 1 | 21 | SN BioScienceINDUSTRY | 1 | Jan 27, 2026 | clinicaltrials |
| NCT06631326 | HAIC in Combination With PD-1 Inhibitors and Lenvatinib for High Tumor Burden Advanced HCC (CHANCE2416) | completed | — | 244 | First Hospital of China Medical UniversityOTHER | 1 | Jan 27, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Mar 18, 2026source: clinicaltrials