Subtype
Colorectal Carcinoma
CI-CAN-00005005CRCExplore in graph →
344 active trials5 approved drugs22 evidence items
- NCIt
- C2955
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Subtype
CI-CAN-00005005CRCExplore in graph →
Clinical trials
1,010 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (127)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04890054 | Screening More Patients for Colorectal Cancer Through Adapting and Refining Targeted Evidence-Based Interventions in Rural Settings, SMARTER CRC(SMARTER CRC) | completed | N/A | 5,696 | OHSU Knight Cancer InstituteOTHER | 1 | Aug 19, 2025 | clinicaltrials |
| NCT06314750 | Deep Learning Based MRI Radiomics in Predicting the Clinical Risk of Locally Advanced Rectal Cancer | completed | — | 186 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER |
| 0 |
| Aug 14, 2025 |
| clinicaltrials |
| NCT05480306 | Phase 2 Study of DKN-01 in Colorectal Cancer(DeFianCe) | completed | Phase 2 | 188 | Leap Therapeutics, Inc.INDUSTRY | 3 | Aug 3, 2025 | clinicaltrials |
| NCT05934643 | An Observational Cohort Study to Assess the Postop Activity of Colorectal Patients Undergoing Elective Surgery (PHYSPAL)(PHYSPAL) | completed | — | 17 | University of NottinghamOTHER | 1 | Jul 16, 2025 | clinicaltrials |
| NCT02611024 | Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors | completed | Phase 1 / Phase 2 | 316 | PharmaMarINDUSTRY | 6 | Jul 9, 2025 | clinicaltrials |
| NCT00199862 | Safety Study of Radio-labeled huA33 Antibody in Colorectal Cancer | completed | N/A | 30 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jul 4, 2025 | clinicaltrials |
| NCT06314971 | Predicting Local and Distant Recurrence in T1 Colorectal Cancer(T1CR) | completed | — | 138 | City of Hope Medical CenterOTHER | 3 | Jul 3, 2025 | clinicaltrials |
| NCT03630354 | EXERCISING TOGETHER for Couples Coping With Cancer | completed | N/A | 496 | OHSU Knight Cancer InstituteOTHER | 1 | Jul 1, 2025 | clinicaltrials |
| NCT06414304 | Dynamics of MSI and Genomic Profile of Colorectal Cancer In the Course of Immune Checkpoint Inhibitor Therapy(BLOOMSI) | completed | — | 30 | OncoAtlas LLCINDUSTRY | 1 | Jun 27, 2025 | clinicaltrials |
| NCT03267524 | Walking for Recovery From Surgery in Improving Quality of Life in Older Adults With Lung or Gastrointestinal Cancer and Their Family Caregivers | completed | N/A | 87 | City of Hope Medical CenterOTHER | 1 | Jun 22, 2025 | clinicaltrials |
| NCT02368886 | Lower or Standard Dose Regorafenib in Treating Patients With Refractory Metastatic Colorectal Cancer | completed | Phase 2 | 123 | Academic and Community Cancer Research UnitedOTHER | 1 | Jun 18, 2025 | clinicaltrials |
| NCT03642067 | Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer | completed | Phase 2 | 59 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jun 15, 2025 | clinicaltrials |
| NCT04554836 | MoLiMoR - A Study With FOLFIRI-based First-line Therapy With or Without Intermittent Cetuximab | completed | Phase 2 | 6 | TheraOpOTHER | 1 | Jun 8, 2025 | clinicaltrials |
| NCT06978595 | Primary Colorectal Signet Ring Cell Carcinoma and the Risk of Multiple Primary Gastrointestinal Malignancies | completed | — | 8,171 | asmaa salama ibrahimOTHER | 1 | May 18, 2025 | clinicaltrials |
| NCT06950996 | A Clinical Evaluation of AI Solutions Developed in the CHAIMELEON Project for Cancer: Prostate, Lung, Breast, Colon and Rectum | completed | — | 300 | Instituto de Investigacion Sanitaria La FeOTHER | 1 | Apr 30, 2025 | clinicaltrials |
| NCT03428958 | A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment | completed | Phase 1 / Phase 2 | 111 | NuCana plcOTHER | 3 | Apr 23, 2025 | clinicaltrials |
| NCT04441580 | Assessing the Additional Neoplasia Yield of Computer-aided Colonoscopy in a Screening Setting(GENIAL-CO) | completed | N/A | 900 | Fondazione Poliambulanza Istituto OspedalieroOTHER | 1 | Apr 10, 2025 | clinicaltrials |
| NCT03597581 | A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer | completed | Phase 1 | 89 | Inspirna, Inc.INDUSTRY | 1 | Apr 3, 2025 | clinicaltrials |
| NCT04761614 | Riluzole in Combination With mFOLFOX6 and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 1 | 13 | Ning JinOTHER | 1 | Mar 28, 2025 | clinicaltrials |
| NCT03506321 | Comparison of the Benefit of Chromoendoscopy in Addition to High Definition White Light and Narrow Band Imaging for the Prediction of Submucosal Invasive Cancer in Colonic Lesions(LANS) | completed | N/A | 400 | Western Sydney Local Health DistrictOTHER | 1 | Mar 27, 2025 | clinicaltrials |
| NCT00545545 | Safety/Efficacy Study of Imprime PGG With Cetuximab in Patients With Recurrent/Progressive Colorectal Carcinoma | completed | Phase 1 / Phase 2 | 32 | HiberCell, Inc.INDUSTRY | 1 | Mar 19, 2025 | clinicaltrials |
| NCT06233253 | Online Mindfulness-Based Intervention to Decrease Pre-Procedural Anxiety Before a First-Time Screening Colonoscopy | completed | N/A | 100 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Feb 24, 2025 | clinicaltrials |
| NCT04015804 | Robotic Low Rectum Anterior Resection(GROG-R01) | completed | N/A | 833 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 3 | Feb 12, 2025 | clinicaltrials |
| NCT02188264 | Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer | completed | Phase 1 | 40 | National Cancer Institute (NCI)NIH | 2 | Feb 11, 2025 | clinicaltrials |
| NCT01638533 | Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction | completed | Phase 1 | 37 | National Cancer Institute (NCI)NIH | 2 | Feb 7, 2025 | clinicaltrials |
| NCT01652196 | Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer | completed | Phase 2 | 56 | John HaysOTHER | 1 | Feb 5, 2025 | clinicaltrials |
| NCT01814501 | Panitumumab and Chemotherapy in Patients With Advanced Colorectal Cancer After Prior Therapy With Bevacizumab | completed | Phase 2 | 16 | John HaysOTHER | 1 | Feb 5, 2025 | clinicaltrials |
| NCT05792735 | Neoadjuvant Cadonilimab Plus Chemotherapy Following Short-Course Radiotherapy in Locally Advanced Rectal Cancer(NeoCaCRT) | completed | Phase 2 | 27 | Shenzhen People's HospitalOTHER | 1 | Feb 5, 2025 | clinicaltrials |
| NCT02000050 | Phase II Study of Up-front Chemotherapy and Neo-adjuvant Short-course Radiotherapy for Resectable Rectal Carcinoma (COLORE)(COLORE) | completed | Phase 2 | 52 | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSOTHER | 1 | Jan 30, 2025 | clinicaltrials |
| NCT06799182 | Periodontal Disease and Colorectal Cancer(PD and CRC) | completed | N/A | 20 | University Medical Centre LjubljanaOTHER | 1 | Jan 29, 2025 | clinicaltrials |
| NCT06789224 | Validation Study on the Removal of EpCAM-positive Tumour Cells From Blood Collected During Tumour Surgery Using Catumaxomab/Catuvab Device(REMOVE) | completed | N/A | 136 | Lindis Bloodcare GmbHINDUSTRY | 1 | Jan 23, 2025 | clinicaltrials |
| NCT06108596 | Evaluation of the Efficacy and Safety of Interleucin-2 Combined With PD-1 Monoclonal Antibody and CAPOX in Preoperative Neoadjuvant Therapy for Mid-low Locally Advanced Rectal Cancer - a Single-center, Single-arm, Open-label Clinical Trail(PICS) | completed | Phase 2 | 33 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Jan 21, 2025 | clinicaltrials |
| NCT03287453 | Educational Intervention - Improving Knowledge and Screening Rates for Colorectal Cancer | completed | N/A | 108 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Jan 9, 2025 | clinicaltrials |
| NCT05716477 | Blood Test (Guardant Shield™) for Screening of Colorectal Cancer in Underserved Patients | completed | — | 146 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Jan 9, 2025 | clinicaltrials |
| NCT04731467 | A Study of CM24 in Combination with Nivolumab in Adults with Advanced Solid Tumors | completed | Phase 1 / Phase 2 | 79 | Famewave Ltd.INDUSTRY | 3 | Dec 27, 2024 | clinicaltrials |
| NCT01640522 | Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms(CaSSY) | completed | N/A | 261 | University of PittsburghOTHER | 1 | Dec 13, 2024 | clinicaltrials |
| NCT03436563 | M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability | completed | Phase 1 / Phase 2 | 4 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 27, 2024 | clinicaltrials |
| NCT03043313 | Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer | completed | Phase 2 | 117 | Seagen Inc.INDUSTRY | 5 | Nov 26, 2024 | clinicaltrials |
| NCT03699163 | The Colorectal Breath Analysis (COBRA) Study(COBRA) | completed | — | 1,855 | Imperial College LondonOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT06686953 | The Effect of Environmental Pollution on Colorectal Cancer | completed | — | 6,300 | Dong PengOTHER | 0 | Nov 13, 2024 | clinicaltrials |
| NCT06638957 | Impact of the COVID-19 Pandemic on Oncologic Outcomes in Colorectal Cancer | completed | — | 14,951 | In Ja ParkOTHER | 1 | Oct 15, 2024 | clinicaltrials |
| NCT03087591 | APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery | completed | Phase 1 | 11 | Wake Forest University Health SciencesOTHER | 1 | Oct 10, 2024 | clinicaltrials |
| NCT02563002 | Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177) | completed | Phase 3 | 307 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Oct 3, 2024 | clinicaltrials |
| NCT06621225 | Artificial Intelligence in Colonoscopy(AIColonoscopy) | completed | N/A | 264 | Pankaj PatelOTHER | 1 | Oct 1, 2024 | clinicaltrials |
| NCT01210313 | Physical Activity for Reduction of Recurrence Rate After Adjuvant Chemotherapy for Localised Colorectal Carcinoma | completed | — | 30 | Austrian Breast & Colorectal Cancer Study GroupNETWORK | 1 | Sep 19, 2024 | clinicaltrials |
| NCT04474470 | A Study to Evaluate NT219 Alone and in Combination with ERBITUX® (Cetuximab) in Adults with Advanced Solid Tumors and Head and Neck Cancer | completed | Phase 1 / Phase 2 | 52 | TyrNovo Ltd.INDUSTRY | 2 | Sep 19, 2024 | clinicaltrials |
| NCT03800602 | Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer | completed | Phase 2 | 29 | Emory UniversityOTHER | 1 | Sep 5, 2024 | clinicaltrials |
| NCT03263429 | Novel PET/CT Imaging Biomarkers of CB-839 in Combination With Panitumumab and Irinotecan in Patients With Metastatic and Refractory RAS Wildtype Colorectal Cancer | completed | Phase 1 / Phase 2 | 29 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | Aug 30, 2024 | clinicaltrials |
| NCT02873195 | Capecitabine and Bevacizumab With or Without Atezolizumab in Treating Patients With Refractory Metastatic Colorectal Cancer | completed | Phase 2 | 133 | Academic and Community Cancer Research UnitedOTHER | 1 | Aug 23, 2024 | clinicaltrials |
Data updated 22 days agoSource updated Aug 19, 2025source: clinicaltrials