Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,060 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04841434 | A Phase I/II Study to Investigate the Use of VORAXAZE™ As Intended Intervention in Patients with CNSL(VALIDATE) | completed | Phase 1 / Phase 2 | 18 | Charite University, Berlin, GermanyOTHER | 1 | Jan 6, 2025 | clinicaltrials |
| NCT06752824 | Analgesia Nociception Index (ANI) in Intracranial Surgical Anesthesia(ANI) | completed | — | 75 | Trakya UniversityOTHER | 1 |
| Dec 31, 2024 |
| clinicaltrials |
| NCT01752491 | A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme | completed | Phase 1 | 13 | Joseph J. Cullen, MD, FACSOTHER | 1 | Dec 20, 2024 | clinicaltrials |
| NCT04028479 | The Registry of Oncology Outcomes Associated With Testing and Treatment(ROOT) | completed | — | 167 | Taproot HealthINDUSTRY | 1 | Dec 18, 2024 | clinicaltrials |
| NCT02901925 | A Microdose Evaluation Study of ABY-029 in Recurrent Glioma(ABY-029) | completed | Early Phase 1 | 14 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Dec 13, 2024 | clinicaltrials |
| NCT03677713 | Nasal Packing Following Endoscopic Endonasal Pituitary Resection | completed | N/A | 60 | Ottawa Hospital Research InstituteOTHER | 1 | Dec 13, 2024 | clinicaltrials |
| NCT04428879 | Topotecan Episcleral Plaque for Treatment of Retinoblastoma(STEP-RB) | completed | Phase 1 | 26 | The Hospital for Sick ChildrenOTHER | 1 | Dec 13, 2024 | clinicaltrials |
| NCT05832450 | Predictive Model to Calculate the Risk of RBC Transfusion in Elective Brain Tumours Resections (TScoreBTR)(TScoreBTR) | completed | — | 1,434 | Clinica Universidad de Navarra, Universidad de NavarraOTHER | 1 | Dec 13, 2024 | clinicaltrials |
| NCT05015543 | Physical Training in Glioblastoma Patients During Cytotoxic Therapy(MMH) | completed | N/A | 54 | University Hospital MuensterOTHER | 1 | Dec 12, 2024 | clinicaltrials |
| NCT03233204 | Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial) | completed | Phase 2 | 6 | National Cancer Institute (NCI)NIH | 2 | Dec 11, 2024 | clinicaltrials |
| NCT01291420 | Dendritic Cell Vaccination for Patients with Solid Tumors | completed | Phase 1 / Phase 2 | 48 | University Hospital, AntwerpOTHER | 1 | Dec 9, 2024 | clinicaltrials |
| NCT01464177 | Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme(GBM Hypo RT) | completed | Phase 2 | 40 | Andre Tsin Chih ChenOTHER | 1 | Dec 9, 2024 | clinicaltrials |
| NCT06557967 | Study on Prevalence and Impact of Brain Metastases on Survival in Lung Cancer by Line of Treatment | completed | — | 22,517 | Daiichi SankyoINDUSTRY | 1 | Dec 9, 2024 | clinicaltrials |
| NCT01130077 | A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction with Poly-ICLC in Pediatric Gliomas | completed | Phase 1 | 60 | James FelkerOTHER | 1 | Dec 6, 2024 | clinicaltrials |
| NCT01595139 | MicroRNAs in Patients With Neurofibromatosis Type 1 | completed | — | 9 | Ann & Robert H Lurie Children's Hospital of ChicagoOTHER | 1 | Dec 6, 2024 | clinicaltrials |
| NCT04109209 | Psychological Intervention For Brain Tumor Caregivers | completed | N/A | 120 | Massachusetts General HospitalOTHER | 1 | Dec 5, 2024 | clinicaltrials |
| NCT06713395 | PERMA-Based Intervention on Negative Emotions, Adherence, and Complications in Postoperative Glioma Patients(Glioma) | completed | N/A | 124 | Yang HuangOTHER_GOV | 1 | Dec 3, 2024 | clinicaltrials |
| NCT04267146 | Nivolumab in Combination With Temozolomide and Radiotherapy in Children and Adolescents With Newly Diagnosed High-grade Glioma(NIVOGLIO) | completed | Phase 1 / Phase 2 | 41 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Dec 2, 2024 | clinicaltrials |
| NCT04726397 | UNIty-Based MR-Linac Guided AdapTive RadiothErapy for High GraDe Glioma: a Phase 2 Trial(UNITED) | completed | N/A | 108 | Sunnybrook Health Sciences CentreOTHER | 1 | Nov 29, 2024 | clinicaltrials |
| NCT02530320 | Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Patients With Oligodendroglioma or Recurrent Oligoastrocytoma Anaplastic With the Activity of the Protein RB Preserved | completed | Phase 2 | 34 | Grupo Español de Investigación en NeurooncologíaOTHER | 1 | Nov 22, 2024 | clinicaltrials |
| NCT02549833 | Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma | completed | Phase 1 | 28 | Jennie TaylorOTHER | 1 | Nov 22, 2024 | clinicaltrials |
| NCT04097535 | Measuring Fatty Acid Oxidation in Gliomas Using 18F-FPIA PET/MRI | completed | — | 11 | Imperial College LondonOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT04217694 | Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors | completed | Early Phase 1 | 18 | Mayo ClinicOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT03232424 | NovoTTF-200A and Temozolomide Chemoradiation for Newly Diagnosed Glioblastoma | completed | Phase 1 | 12 | Hackensack Meridian HealthOTHER | 1 | Nov 18, 2024 | clinicaltrials |
| NCT03964909 | Resting-State Functional MRI in Glioma Patients Before and After Surgery | completed | N/A | 29 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 15, 2024 | clinicaltrials |
| NCT05062772 | Brain Tumor Intraoperative Ultrasound Database(BraTioUS-DB) | completed | — | 150 | Hospital del Rio HortegaOTHER | 5 | Nov 15, 2024 | clinicaltrials |
| NCT03865355 | Blood and Cerebrospinal Fluid Metabolomic Profile in Glioma Patients | completed | — | 50 | Novosibirsk State UniversityOTHER | 1 | Nov 14, 2024 | clinicaltrials |
| NCT03735498 | Psychological Intervention for Caregivers of Patients With Malignant Gliomas | completed | N/A | 13 | Massachusetts General HospitalOTHER | 1 | Nov 13, 2024 | clinicaltrials |
| NCT05807893 | Study to Evaluate the Safety and Efficacy of Serplulimab Plus Bevacizumab and Chemotherapy in NSCLC Patients With Brain Metastases(SUPER BRAIN) | completed | Phase 2 / Phase 3 | 40 | Sun Yat-sen UniversityOTHER | 1 | Nov 13, 2024 | clinicaltrials |
| NCT03732352 | 18F-FDG PET and Osimertinib in Evaluating Glucose Utilization in Patients with EGFR Activated Recurrent Glioblastoma | completed | Phase 2 | 12 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Nov 12, 2024 | clinicaltrials |
| NCT04845919 | Sonodynamic Therapy With ExAblate System in Glioblastoma Patients(Sonic ALA) | completed | Phase 2 | 5 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo BestaOTHER | 1 | Nov 12, 2024 | clinicaltrials |
| NCT01117844 | Proton Radiation For Meningiomas and Hemangiopericytomas | completed | Phase 1 / Phase 2 | 53 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Nov 7, 2024 | clinicaltrials |
| NCT01682187 | A Dose-Escalation Study in Participants With Recurrent Malignant Glioma | completed | Phase 1 | 66 | Eli Lilly and CompanyINDUSTRY | 2 | Nov 7, 2024 | clinicaltrials |
| NCT02101905 | Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma | completed | Phase 1 | 29 | National Cancer Institute (NCI)NIH | 1 | Nov 6, 2024 | clinicaltrials |
| NCT05448690 | Comparative Effectiveness of Different Surgical Approaches for Giant Pituitary Adenomas | completed | N/A | 600 | Huashan HospitalOTHER | 1 | Oct 29, 2024 | clinicaltrials |
| NCT06620926 | Impact of IDH Mutation and Adjuvant Chemo(radio)therapy on Survival Outcome in Grade II/III Astrocytoma | completed | — | 811 | asmaa salama ibrahimOTHER | 1 | Oct 29, 2024 | clinicaltrials |
| NCT03323034 | Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphoma | completed | Phase 1 | 30 | Children's Oncology GroupNETWORK | 1 | Oct 22, 2024 | clinicaltrials |
| NCT03922984 | Non-Contrast Perfusion Using Arterial Spin Labeled MR Imaging for Assessment of Therapy Response in Glioblastoma | completed | N/A | 43 | University of Texas Southwestern Medical CenterOTHER | 1 | Oct 22, 2024 | clinicaltrials |
| NCT05427214 | Imaging Study on Halcyon 4.0 System for Patients Receiving Radiation Therapy(Dragon) | completed | N/A | 52 | Washington University School of MedicineOTHER | 1 | Oct 21, 2024 | clinicaltrials |
| NCT04304300 | Radiotherapy in IDH Mutated Glioma: Evaluation of Late Outcomes(RIGEL) | completed | — | 80 | Erasmus Medical CenterOTHER | 1 | Oct 15, 2024 | clinicaltrials |
| NCT03926507 | F18 Fluciclovine PET/CT in Assessing Tumor Volume and Radiation Therapy Response in Patients With Glioblastoma Undergoing Surgery | completed | N/A | 12 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 9, 2024 | clinicaltrials |
| NCT03936465 | Study of the Bromodomain (BRD) and Extra-Terminal Domain (BET) Inhibitors BMS-986158 and BMS-986378 in Pediatric Cancer | completed | Phase 1 | 41 | Dana-Farber Cancer InstituteOTHER | 2 | Oct 2, 2024 | clinicaltrials |
| NCT01794793 | Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies | completed | Phase 4 | 337 | RECORDATI GROUPINDUSTRY | 28 | Oct 1, 2024 | clinicaltrials |
| NCT03071913 | Blood Brain Barrier Differences in Patients with Brain Tumors Undergoing Surgery | completed | — | 54 | Mayo ClinicOTHER | 1 | Sep 27, 2024 | clinicaltrials |
| NCT03294434 | Predicting Sites of Tumour Progression in the Invasive Margin of Glioblastomas (PRaM-GBM Study)(PRaM-GBM) | completed | — | 147 | CCTU- Cancer ThemeOTHER | 1 | Sep 27, 2024 | clinicaltrials |
| NCT01149850 | Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma | completed | Phase 2 | 50 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT01811992 | Combined Cytotoxic and Immune-Stimulatory Therapy for Glioma | completed | Phase 1 | 19 | University of Michigan Rogel Cancer CenterOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT03234595 | A Phase I/IIa Study of Cerebraca Wafer Plus Adjuvant Temozolomide (TMZ) in Patients With Recurrent High Grade Glioma | completed | Phase 1 / Phase 2 | 22 | Everfront Biotech Co., Ltd.INDUSTRY | 1 | Sep 19, 2024 | clinicaltrials |
| NCT03278249 | Feasibility Study of Modified Atkins Ketogenic Diet in the Treatment of Newly Diagnosed Malignant Glioma | completed | N/A | 12 | University of CincinnatiOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT03661723 | Pembrolizumab and Reirradiation in Bevacizumab Naïve and Bevacizumab Resistant Recurrent Glioblastoma | completed | Phase 2 | 60 | Dana-Farber Cancer InstituteOTHER | 1 | Sep 19, 2024 | clinicaltrials |
Data updated 23 days agoSource updated Jan 6, 2025source: clinicaltrials