Clinical trial · Observational
Predictive Model to Calculate the Risk of RBC Transfusion in Elective Brain Tumours Resections (TScoreBTR)
Validation of a Predictive Model to Calculate the Risk of Red Blood Cells Concentrates Transfusion in Patients Undergoing Elective Brain Tumours Resections
NCT05832450CI-TRIAL-00083710TScoreBTRcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To validate a predictive model for the risk of receiving RBCs in this population. This model uses four preoperative values (haemoglobin levels, tumour volume, previous craniotomy in the same spot, and number of craniotomies foreseen). The investigators would like to create an online data collection tool and calculator.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Tumor Adult | Brain Neoplasm | ALIAS | 0.85 |
| Surgery | — | UNRESOLVED | — |
| Transfusion | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Red cell concentrate transfusion | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- No intervention
- description
- Perioperative data of patient undergoing elective brain tumor resection without requirements of red cell concentrate transfusion.
- interventionNames
- Other: Red cell concentrate transfusion
Primary outcomes (2)
- measure
- Number of red cell concentrate transfused
- timeFrame
- During the surgery
- description
- Number of red cell concentrate transfused
- measure
- Number of red cell concentrate transfused
- timeFrame
- Immediately (first 24 hours) after the surgery
- description
- Number of red cell concentrate transfused
Secondary outcomes (4)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: \- Brain tumour (primary or metastatic) patients undergoing craniotomy for resection. Exclusion Criteria: * Patients younger than 18 years old. * Urgent/emergent surgery. * Brain tumours not requiring full craniotomy. * Patients with blood conditions causing coagulation abnormalities. * Systemic disease associated with significant abnormalities in coagulation times (prothrombin time \<60% or activated thromboplastin time \> 50 sg).
References
Publications (3)
- RESULTTomas-Biosca A, Martinez-Simon A, Guridi J, Honorato-Cia C, Cacho-Asenjo E, Tejada Solis S, Bejarano B, Becerra-Castro MV, Nunez-Cordoba JM. Development and Performance Evaluation of a Clinical Predictive Model to Estimate the Risk of Red Blood Cell Requirements in Brain Tumor Surgery. J Neurosurg Anesthesiol. 2023 Jan 1;35(1):74-79. doi: 10.1097/ANA.0000000000000793. Epub 2021 Aug 16. PMID 34393176
- RESULTTomas-Biosca A, Martinez-Simon A, Guridi J, Tejada Solis S, Bejarano B, Honorato-Cia C, Cacho-Asenjo E, Nunez-Cordoba JM. Preoperative Hemoglobin and Actual Need for Blood Transfusion in Brain Tumor Resection Procedures: A Retrospective Cohort Study. J Neurosurg Anesthesiol. 2022 Apr 1;34(2):251-252. doi: 10.1097/ANA.0000000000000753. No abstract available. PMID 33470594
- DERIVEDContreras-Lopez L, Clavero FI, Hurtado Restrepo PA, de Arriba NP, Alvarez AD, Montes Armenteros JA, Pellicena MP, Colorado AF, Asensi PD, Candil JF, Garcia LG, Albamonte PS, Krauchi OR, Nunez-Cordoba JM, Martinez-Simon A. Efficiency in packed red blood management for brain tumor resection: multicenter prospective cohort study (TScoreBTR). Blood Transfus. 2026 Jan-Feb;24(1):56-64. doi: 10.2450/BloodTransfus.1069. Epub 2025 Aug 28. PMID 40901795