Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,058 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03893110 | Carbon PEEK Versus Titanium Pedicle Screws in the Treatment of Spinal Tumors | withdrawn | N/A | 0 | Balgrist University HospitalOTHER | 1 | Sep 24, 2026 | clinicaltrials |
| NCT06485310 | Interest of a TEteleconsultation of a Psychological Support Nurse on Psychological Distress in Patients With a Primary Malignancy of the Central Nervous System(TECAP) | withdrawn | N/A | 0 | Centre Hospitalier Universitaire de la RéunionOTHER | 0 | Sep 23, 2026 |
| clinicaltrials |
| NCT04298541 | Direct Comparison of Ga-68-DOTATATE and Ga-68-DOTATOC | withdrawn | Phase 2 | 0 | Weill Medical College of Cornell UniversityOTHER | 1 | Aug 31, 2026 | clinicaltrials |
| NCT07660458 | Parental Distress and Treatment Adherence in Pediatric Recurrent Medulloblastoma | withdrawn | — | 0 | West China HospitalOTHER | 1 | Aug 19, 2026 | clinicaltrials |
| NCT07449481 | A Phase II Clinical Study of Utidelone and Bevacizumab With or Without Etoposide in Patients With Brain Metastases From Malignant Solid Tumors | withdrawn | Phase 2 | 0 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Jul 16, 2026 | clinicaltrials |
| NCT06455189 | Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas | withdrawn | Phase 1 | 0 | Case Comprehensive Cancer CenterOTHER | 1 | Jul 1, 2026 | clinicaltrials |
| NCT04500548 | Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study | withdrawn | Phase 1 | 0 | National Cancer Institute (NCI)NIH | 2 | Jun 10, 2026 | clinicaltrials |
| NCT05218408 | CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type(CYNK001GBM02) | withdrawn | Phase 1 / Phase 2 | 0 | Celularity IncorporatedINDUSTRY | 0 | Jun 8, 2026 | clinicaltrials |
| NCT03554707 | SGT-53 in Children With Recurrent or Progressive CNS Malignancies | withdrawn | Early Phase 1 | 0 | SynerGene Therapeutics, Inc.INDUSTRY | 1 | May 8, 2026 | clinicaltrials |
| NCT04105374 | Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma | withdrawn | Phase 2 / Phase 3 | 0 | NRG OncologyOTHER | 0 | May 7, 2026 | clinicaltrials |
| NCT04084431 | Supportive Care With or Without Repeated Whole Brain Radiotherapy in Patients With Recurrent Brain Metastases(RECARE) | withdrawn | N/A | 0 | University Hospital HeidelbergOTHER | 1 | May 5, 2026 | clinicaltrials |
| NCT07553520 | Dietary Cysteine and Methionine Deprivation (CMD) in Glioma Patients | withdrawn | N/A | 0 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT04533919 | Validation of Pre-clinical Nano-Based Analgesics in Cells From Human Dorsal Root Ganglia | withdrawn | — | 0 | M.D. Anderson Cancer CenterOTHER | 0 | Apr 6, 2026 | clinicaltrials |
| NCT04482933 | HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma | withdrawn | Phase 2 | 0 | Pediatric Brain Tumor ConsortiumNETWORK | 1 | Feb 10, 2026 | clinicaltrials |
| NCT06012929 | A Study of ONC201 for Refractory Meningioma | withdrawn | Phase 2 | 0 | University of NebraskaOTHER | 0 | Jan 26, 2026 | clinicaltrials |
| NCT05669326 | Evaluation of the Contribution of NODDI Protocol Tractography in Brain Tumor Surgery(NODDI-TRACT) | withdrawn | N/A | 0 | GCS Ramsay Santé pour l'Enseignement et la RechercheOTHER | 1 | Dec 3, 2025 | clinicaltrials |
| NCT06776406 | Head Stabilization in Whole Brain RT | withdrawn | N/A | 0 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Nov 25, 2025 | clinicaltrials |
| NCT05904704 | Oxygen-Enhanced MRI for Generating Hypoxia Maps in Patients With Intracranial Tumors | withdrawn | N/A | 0 | OHSU Knight Cancer InstituteOTHER | 1 | Nov 14, 2025 | clinicaltrials |
| NCT05341947 | Activated Autologous T Cells Against Glioma Cancer Stem Cell Antigens for Patients With Recurrent Glioblastoma | withdrawn | Phase 1 | 0 | Jeremy Rudnick, M.DOTHER | 1 | Oct 22, 2025 | clinicaltrials |
| NCT05720624 | Pharmacodynamic Analyses of Metabolic Agents Following Brain Radiation | withdrawn | Phase 1 | 0 | Mayo ClinicOTHER | 1 | Oct 22, 2025 | clinicaltrials |
| NCT04344652 | Photoscreening for Retinoblastoma | withdrawn | N/A | 0 | Phoenix Children's HospitalOTHER | 0 | Sep 26, 2025 | clinicaltrials |
| NCT05789862 | Behavioral Health Evaluation and Intervention Program for Patients Undergoing Craniotomy | withdrawn | N/A | 0 | University of California, San FranciscoOTHER | 0 | Aug 29, 2025 | clinicaltrials |
| NCT07011849 | Study of Lenvatinib Plus Pembrolizumab in IO Refractory mRCC Patients With Brain Metastases | withdrawn | Phase 2 | 0 | M.D. Anderson Cancer CenterOTHER | 0 | Aug 13, 2025 | clinicaltrials |
| NCT04118036 | Abemaciclib + Pembrolizumab In Glioblastoma | withdrawn | Phase 2 | 0 | Dana-Farber Cancer InstituteOTHER | 1 | Aug 11, 2025 | clinicaltrials |
| NCT06501911 | A Study of Bicalutamide With Brain Re-irradiation to Treat Recurrent/Progressive High Grade Glioma | withdrawn | Phase 1 | 0 | University of NebraskaOTHER | 1 | Jul 22, 2025 | clinicaltrials |
| NCT04838782 | Role of Repeat Resection in Recurrent Glioblastoma | withdrawn | N/A | 0 | University of AlbertaOTHER | 1 | Jul 8, 2025 | clinicaltrials |
| NCT07046481 | Physical Activity and Quality of Life in Childhood Cancersurvivors- a Long-term Follow-up | withdrawn | N/A | 0 | Region SkaneOTHER | 0 | Jul 1, 2025 | clinicaltrials |
| NCT05620914 | A Window of Opportunity Study of Patritumab Deruxtecan in Patients With Brain Metastases(PARAMETer) | withdrawn | Phase 2 | 0 | Mustafa Khasraw, MBChB, MD, FRCP, FRACPOTHER | 1 | Jun 15, 2025 | clinicaltrials |
| NCT06494046 | Defining Musical Toxicity and Its Effect on Patient Well-being | withdrawn | — | 0 | Mayo ClinicOTHER | 1 | Jun 4, 2025 | clinicaltrials |
| NCT05927610 | Genetic Testing of Cerebrospinal Fluid to Diagnose and Monitor Glioblastoma | withdrawn | N/A | 0 | Memorial Sloan Kettering Cancer CenterOTHER | 0 | May 21, 2025 | clinicaltrials |
| NCT02145910 | Vemurafenib Combined With Whole Brain Radiation Therapy or Radiosurgery in Patients With BRAF Mutation-Positive Melanoma and Brain Metastases | withdrawn | Phase 1 | 0 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 0 | May 2, 2025 | clinicaltrials |
| NCT04667715 | Safety and Effectiveness of Blood-Brain Barrier Disruption (BBBD) in Subjects With Suspected Infiltrating Glioma(BBBD) | withdrawn | N/A | 0 | InSightecINDUSTRY | 1 | May 2, 2025 | clinicaltrials |
| NCT05900908 | Post-operative Adjuvant Therapy w/wo GammaTile + Systemic Therapy(PATHWAyS) | withdrawn | Phase 4 | 0 | GT Medical Technologies, Inc.INDUSTRY | 0 | Apr 10, 2025 | clinicaltrials |
| NCT05516485 | Measuring Brain Tumor Consistency Using Magnetic Resonance Elastography | withdrawn | N/A | 0 | University of Southern CaliforniaOTHER | 1 | Mar 4, 2025 | clinicaltrials |
| NCT05457959 | Peptide-Pulsed Dendritic Cell Vaccination in Combination With Nivolumab and Ipilimumab for the Treatment of Recurrent and/or Progressive Diffuse Hemispheric Glioma, H3 G34-mutant | withdrawn | Phase 1 | 0 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Feb 24, 2025 | clinicaltrials |
| NCT06328036 | Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma | withdrawn | Phase 2 | 0 | National Cancer Institute (NCI)NIH | 0 | Dec 30, 2024 | clinicaltrials |
| NCT05973903 | Lenvatinib, Pembrolizumab, and Tumor Treating Fields (TTFields) for Second-line Treatment of Glioblastoma | withdrawn | Phase 1 / Phase 2 | 0 | Tel Aviv Medical CenterOTHER | 0 | Dec 4, 2024 | clinicaltrials |
| NCT06463184 | Study to Assess Xevinapant in Preoperative Subjects With Recurrent High-Grade Glioma (rHGG) | withdrawn | Phase 1 | 0 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 0 | Dec 4, 2024 | clinicaltrials |
| NCT05879120 | Randomized Study of Neo-adjuvant and Adjuvant Pembrolizumab With and Without Targeted Blood Brain Barrier Opening Using Exablate MRI-guided Focused Ultrasound (Exablate MRgFUS) for Recurrent Glioblastoma | withdrawn | Phase 2 | 0 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 20, 2024 | clinicaltrials |
| NCT04521946 | Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer | withdrawn | Phase 1 | 0 | M.D. Anderson Cancer CenterOTHER | 0 | Oct 26, 2024 | clinicaltrials |
| NCT03990597 | StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord | withdrawn | Phase 1 | 0 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 9, 2024 | clinicaltrials |
| NCT05773664 | Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients with Glioblastoma | withdrawn | Phase 1 | 0 | City of Hope Medical CenterOTHER | 0 | Sep 19, 2024 | clinicaltrials |
| NCT02795338 | Multi-modality Localization of Eloquent Brain Function | withdrawn | — | 0 | University of NebraskaOTHER | 0 | Sep 3, 2024 | clinicaltrials |
| NCT03925675 | 18F-Fluciclovine PET and Multiparametric MR Imaging | withdrawn | Phase 2 | 0 | Loma Linda UniversityOTHER | 1 | Sep 3, 2024 | clinicaltrials |
| NCT05082493 | A Multicenter, Study of the Safety and Pharmacokinetics of Intravenously Infused Berubicin in Pediatric Patients With Progressive, Refractory, or Recurrent High Grade Gliomas | withdrawn | Phase 1 | 0 | WPD Pharmaceuticals Sp. z o.o.INDUSTRY | 0 | Jun 6, 2024 | clinicaltrials |
| NCT03955068 | Strict Classic Ketogenic Diet as a Therapy for Recurrent or Progressive and Refractory Brain Tumors in Children | withdrawn | N/A | 0 | University of Texas Southwestern Medical CenterOTHER | 1 | May 22, 2024 | clinicaltrials |
| NCT01622764 | 89Zr-RO5323441 PET Imaging in Glioblastoma | withdrawn | Phase 2 | 0 | University Medical Center GroningenOTHER | 1 | May 6, 2024 | clinicaltrials |
| NCT05120960 | A Phase 1a/1b Study to Determine the Recommended Phase 2 Dose, of Tepotinib in Participants With MET Alterations and Brain Tumors | withdrawn | Phase 1 | 0 | M.D. Anderson Cancer CenterOTHER | 0 | Apr 17, 2024 | clinicaltrials |
| NCT05304663 | Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Progression(GLIOASTRA) | withdrawn | Phase 1 | 0 | Philogen S.p.A.INDUSTRY | 0 | Apr 8, 2024 | clinicaltrials |
Data updated 5 days agoSource updated Sep 24, 2026source: clinicaltrials