Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
Loading cancer entity…
Loading cancer entity…
Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,060 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02781792 | Temozolomide Chronotherapy for High Grade Glioma | completed | Phase 2 | 42 | Washington University School of MedicineOTHER | 1 | Jun 27, 2025 | clinicaltrials |
| NCT02514915 | Pre-operative Stereotactic Radiosurgery Followed by Resection for Brain Metastases | completed | N/A | 24 | Christopher WilkeOTHER | 1 | Jun 26, 2025 | clinicaltrials |
| NCT02601950 |
| A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma |
| completed |
| Phase 2 |
| 267 |
| Epizyme, Inc.INDUSTRY |
| 9 |
| Jun 22, 2025 |
| clinicaltrials |
| NCT04320108 | ESWT for Shoulder Pain in Patients With Brain Damage | completed | N/A | 6 | Bundang CHA HospitalOTHER | 1 | Jun 19, 2025 | clinicaltrials |
| NCT05362409 | Study to Evaluate 5-ALA Combined With CV01 Delivery of Ultrasound in Recurrent High Grade Glioma | completed | Phase 1 | 22 | Alpheus Medical, Inc.INDUSTRY | 1 | Jun 19, 2025 | clinicaltrials |
| NCT02667587 | An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)(CheckMate548) | completed | Phase 3 | 716 | Bristol-Myers SquibbINDUSTRY | 19 | Jun 18, 2025 | clinicaltrials |
| NCT04734444 | SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue | completed | N/A | 45 | SonoClear ASINDUSTRY | 3 | Jun 17, 2025 | clinicaltrials |
| NCT04610229 | Safety of IMRT Treatment With Inhomogeneous Dose in Patients With Relapsed High-grade Gliomas.(GLIORAD) | completed | N/A | 12 | Azienda USL Reggio Emilia - IRCCSOTHER_GOV | 1 | Jun 12, 2025 | clinicaltrials |
| NCT03567486 | Predictive Factors of Visual Recovery After Paraoptic Tumors Removal(PRONOPTIC) | completed | — | 99 | Fondation Ophtalmologique Adolphe de RothschildNETWORK | 1 | Jun 11, 2025 | clinicaltrials |
| NCT04740190 | Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd(TAC-GReD) | completed | Phase 2 | 33 | The University of Hong KongOTHER | 1 | Jun 11, 2025 | clinicaltrials |
| NCT02655601 | Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001(BMX-HGG) | completed | Phase 1 / Phase 2 | 177 | BioMimetix JV, LLCINDUSTRY | 1 | Jun 8, 2025 | clinicaltrials |
| NCT05822817 | Comparison of Postoperative Recovery of Sevoflurane and Propofol After Transsphenoidal Surgery | completed | Phase 4 | 252 | Peking Union Medical College HospitalOTHER | 1 | Jun 8, 2025 | clinicaltrials |
| NCT04749641 | Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine Glioma(ENACTING) | completed | Phase 1 | 16 | Yang ZhangOTHER | 1 | Jun 6, 2025 | clinicaltrials |
| NCT06255249 | Multicenter Evaluation in Patients With MEningiomas of the Response to Treatment With 177LUTEtium-oxodotreotide(MELUTE) | completed | — | 50 | Central Hospital, Nancy, FranceOTHER | 1 | Jun 6, 2025 | clinicaltrials |
| NCT04051606 | Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma | completed | Phase 2 | 14 | Case Comprehensive Cancer CenterOTHER | 1 | Jun 5, 2025 | clinicaltrials |
| NCT04479241 | LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent Glioblastoma | completed | Phase 2 | 25 | Istari Oncology, Inc.INDUSTRY | 1 | Jun 5, 2025 | clinicaltrials |
| NCT04766632 | Contribution of Cerebral 18F-DOPA PET-CT Scan in High-grade Recurrent Gliomas(DORA) | completed | N/A | 16 | Central Hospital, Nancy, FranceOTHER | 1 | Jun 5, 2025 | clinicaltrials |
| NCT06472440 | Evaluation of the Use of a Method "Radiomics" for DOPA PET in Gliomas(RADDOPAG-2) | completed | — | 1,000 | Central Hospital, Nancy, FranceOTHER | 1 | Jun 5, 2025 | clinicaltrials |
| NCT03452930 | Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma | completed | Phase 1 | 5 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 4, 2025 | clinicaltrials |
| NCT01288235 | Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation | completed | Phase 2 | 100 | Massachusetts General HospitalOTHER | 1 | Jun 3, 2025 | clinicaltrials |
| NCT02766699 | A Study to Evaluate the Safety, Tolerability and Immunogenicity of EGFR(V)-EDV-Dox in Subjects With Recurrent GBM(CerebralEDV) | completed | Phase 1 | 9 | Engeneic Pty LimitedINDUSTRY | 1 | Jun 3, 2025 | clinicaltrials |
| NCT03834740 | A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection | completed | Early Phase 1 | 27 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | May 30, 2025 | clinicaltrials |
| NCT02311582 | MK-3475 in Combination With MRI-guided Laser Ablation in Recurrent Malignant Gliomas | completed | Phase 1 / Phase 2 | 55 | Washington University School of MedicineOTHER | 1 | May 29, 2025 | clinicaltrials |
| NCT00526812 | A Safety Study of RTA 744 in Patients With Recurrent High-Grade Gliomas | completed | Phase 1 | 54 | BiogenINDUSTRY | 1 | May 28, 2025 | clinicaltrials |
| NCT03047473 | Avelumab in Patients With Newly Diagnosed Glioblastoma Multiforme(SEJ) | completed | Phase 2 | 38 | Clinique Neuro-OutaouaisOTHER | 1 | May 25, 2025 | clinicaltrials |
| NCT05187624 | A Study Evaluating the Safety, Pharmacokinetic and Anti-tumor Activity of RO7428731 in Participants With Glioblastoma | completed | Phase 1 | 36 | Hoffmann-La RocheINDUSTRY | 5 | May 22, 2025 | clinicaltrials |
| NCT03782415 | Study to Evaluate Ibudilast and TMZ Combo Treatment in Newly Diagnosed and Recurrent Glioblastoma | completed | Phase 1 / Phase 2 | 64 | MediciNovaINDUSTRY | 1 | May 21, 2025 | clinicaltrials |
| NCT03898908 | Encorafenib and Binimetinib Before Local Treatment in Patients With BRAF Mutant Melanoma Metastatic to the Brain(EBRAIN-MEL) | completed | Phase 2 | 48 | Grupo Español Multidisciplinar de MelanomaOTHER | 1 | May 21, 2025 | clinicaltrials |
| NCT01703507 | Phase I Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma | completed | Phase 1 | 17 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT04468919 | Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit(BCI-FIT) | completed | N/A | 55 | Oregon Health and Science UniversityOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT03477110 | Temozolomide, Radiation Therapy, and Tumor Treating Fields Therapy in Treating Participants With Glioblastoma | completed | Early Phase 1 | 30 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT03665545 | Pembrolizumab in Association With the IMA950/Poly-ICLC for Relapsing Glioblastoma(IMA950-106) | completed | Phase 1 / Phase 2 | 18 | University Hospital, GenevaOTHER | 1 | May 13, 2025 | clinicaltrials |
| NCT03496181 | Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently | completed | — | 32 | Memorial Sloan Kettering Cancer CenterOTHER | 2 | May 11, 2025 | clinicaltrials |
| NCT04342572 | Intra-arterial Chemotherapy for Retinoblastoma(IAC) | completed | Phase 1 | 5 | Washington University School of MedicineOTHER | 1 | May 11, 2025 | clinicaltrials |
| NCT02507583 | Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma | completed | Phase 1 | 33 | david andrewsOTHER | 1 | May 7, 2025 | clinicaltrials |
| NCT05289908 | Intrathecal Pemetrexed for Leptomeningeal Metastasis | completed | Phase 1 / Phase 2 | 34 | The First Hospital of Jilin UniversityOTHER | 1 | May 4, 2025 | clinicaltrials |
| NCT00328458 | EPO906 Plus Radiation Therapy for the Treatment of Cancer Patients | completed | Phase 1 | 39 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT00329589 | A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients | completed | Phase 1 | 54 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT00639262 | Combination of Sorafenib and Radiation for Brain Metastases and Primary Brain Tumors | completed | Phase 1 | 35 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT00898755 | Collecting and Storing Tissue From Young Patients With Cancer | completed | — | 213 | Children's Oncology GroupNETWORK | 2 | May 2, 2025 | clinicaltrials |
| NCT01550523 | Pilot Immunotherapy Trial for Recurrent Malignant Gliomas | completed | Phase 1 | 13 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT02186509 | Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas | completed | Phase 1 | 17 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Apr 30, 2025 | clinicaltrials |
| NCT04584866 | Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery(PosESS) | completed | N/A | 54 | University Hospital, Basel, SwitzerlandOTHER | 1 | Apr 29, 2025 | clinicaltrials |
| NCT02392078 | Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System(LAANTERN) | completed | — | 1,153 | Monteris MedicalINDUSTRY | 1 | Apr 24, 2025 | clinicaltrials |
| NCT02026271 | A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma | completed | Phase 1 | 40 | Alaunos TherapeuticsINDUSTRY | 1 | Apr 16, 2025 | clinicaltrials |
| NCT03632135 | Standard Chemotherapy vs. Chemotherapy Guided by Cancer Stem Cell Test in Recurrent Glioblastoma(CSCRGBM) | completed | Phase 3 | 78 | Cordgenics, LLCINDUSTRY | 1 | Apr 15, 2025 | clinicaltrials |
| NCT02715609 | Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma | completed | Phase 1 / Phase 2 | 35 | Washington University School of MedicineOTHER | 1 | Apr 10, 2025 | clinicaltrials |
| NCT05801159 | [18F]FPIA PET-CT in Glioblastoma Multiforme (GBM)(FAM-GBM) | completed | — | 3 | Imperial College LondonOTHER | 1 | Apr 9, 2025 | clinicaltrials |
| NCT06914700 | A Nomogram for Predicting the Diagnosis of Central Malignant Tumors Based on Preoperative Clinical Characteristics and Laboratory Indicators:(PCNSL，GLIOMA) | completed | — | 800 | Guangdong Provincial People's HospitalOTHER | 0 | Apr 9, 2025 | clinicaltrials |
| NCT01604512 | A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor Progression | completed | N/A | 148 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 8, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Jun 27, 2025source: clinicaltrials