Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,058 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06867978 | Multi-center Study on CCeLL-In Vivo's Clinical Efficacy for Intraoperative Brain Tumor Diagnosis.(PRECISION) | not yet recruiting | Phase 1 | 100 | VPIX MedicalINDUSTRY | 0 | Mar 10, 2025 | clinicaltrials |
| NCT06863064 | Brain Tumor Surgery and Postoperative Delirium | not yet recruiting | N/A | 140 | Kaohsiung Medical University Chung-Ho Memorial HospitalOTHER | 1 | Mar 7, 2025 |
| NCT06861218 | Cerebrospinal Fluid Cytology-guided Intrathecal Chemo-holiday Therapy for EGFR-positive NSCLC Leptomeningeal Metastases | not yet recruiting | Phase 2 | 42 | Zhejiang Cancer HospitalOTHER | 1 | Mar 6, 2025 | clinicaltrials |
| NCT06852001 | Efficacy of the RayerKnife X Stereotactic Radiotherapy System in the Treatment of Brain Metastases | not yet recruiting | N/A | 34 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Feb 28, 2025 | clinicaltrials |
| NCT06845020 | CSF Proteomic Characterization of Glioblastomas | not yet recruiting | — | 15 | Univeridad Autonoma de GuadalajaraOTHER | 0 | Feb 25, 2025 | clinicaltrials |
| NCT06780592 | Vebreltinib Combined With Temozolomide for Glioblastoma (GBM) After Surgery | not yet recruiting | Phase 2 | 60 | Huashan HospitalOTHER | 0 | Jan 22, 2025 | clinicaltrials |
| NCT06787807 | Proteomic Analysis of Patients Undergoing Bariatric Surgery | not yet recruiting | N/A | 103 | Universidade Federal de PernambucoOTHER | 1 | Jan 22, 2025 | clinicaltrials |
| NCT06770335 | The FLaME Cognitive Rehabilitation Study for Childhood Brain Tumour(FLaME) | not yet recruiting | N/A | 36 | Great Ormond Street Hospital for Children NHS Foundation TrustOTHER | 1 | Jan 13, 2025 | clinicaltrials |
| NCT06766591 | Ivonescimab Combined With Chemotherapy for the Treatment of Leptomeningeal Metastases Failed to EGFR-TKIs | not yet recruiting | N/A | 36 | Jiangsu Province Nanjing Brain HospitalOTHER | 0 | Jan 9, 2025 | clinicaltrials |
| NCT06764537 | Evaluation of in Vitro Antitumor Activity of GD2 CAR-T Cells in Glioblastoma(BOOSTCAR) | not yet recruiting | N/A | 18 | Central Hospital, Nancy, FranceOTHER | 1 | Jan 8, 2025 | clinicaltrials |
| NCT06742593 | Study of MT027 in Patients with Brain, Meninges, and Spinal Cord Metastatic Solid Tumors | not yet recruiting | Phase 1 | 12 | Suzhou Maximum Bio-tech Co., Ltd.INDUSTRY | 1 | Dec 19, 2024 | clinicaltrials |
| NCT06737146 | Study of MT027 in Patients with Recurrent or Progressive High-grade Glioma | not yet recruiting | Phase 1 | 12 | Suzhou Maximum Bio-tech Co., Ltd.INDUSTRY | 1 | Dec 17, 2024 | clinicaltrials |
| NCT05776706 | Clinical Trial for the Validation of AR Based Neuronavigation System | not yet recruiting | N/A | 80 | Seoul National University HospitalOTHER | 1 | Dec 3, 2024 | clinicaltrials |
| NCT06701838 | Osilodrostat Therapy and 11C-methionine PET to Improve Corticotroph Adenoma Detection(OPTIMAL) | not yet recruiting | — | 15 | Imperial College LondonOTHER | 0 | Dec 3, 2024 | clinicaltrials |
| NCT06684899 | Optimizing Cytokine-Induced Killer Cells in Glioblastoma Patients(KillGlio) | not yet recruiting | — | 40 | IRCCS San RaffaeleOTHER | 0 | Nov 14, 2024 | clinicaltrials |
| NCT06657027 | Artificial Intelligence-Guided Radiotherapy Planning for Glioblastoma(ARTPLAN-GLIO) | not yet recruiting | — | 40 | Hospital del Rio HortegaOTHER | 0 | Oct 24, 2024 | clinicaltrials |
| NCT05897658 | Levetiracetam Prophylaxis in Brain Tumor Resection Pilot(LeviTaTe Pilot) | not yet recruiting | Phase 3 | 70 | Hamilton Health Sciences CorporationOTHER | 0 | Oct 23, 2024 | clinicaltrials |
| NCT06646211 | High-dose Methotrexate Combined with Thiotepa and Zanubrutinib in the Treatment of Newly Diagnosed PCNSL (MTZ) | not yet recruiting | Phase 2 | 30 | Sun Yat-sen UniversityOTHER | 1 | Oct 17, 2024 | clinicaltrials |
| NCT06258018 | Niraparib and Temozolomide in Patients Glioblastoma(ONC-2022-001) | not yet recruiting | Phase 1 / Phase 2 | 86 | Armando Santoro, MDOTHER | 1 | Aug 30, 2024 | clinicaltrials |
| NCT06572592 | The Predictive Value of MRI for Adult-type Diffuse Gliomas(MRI; glioma;) | not yet recruiting | — | 200 | First Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 0 | Aug 27, 2024 | clinicaltrials |
| NCT04933422 | CM93 Treatment in Subjects With Epidermal Growth Factor Receptor (EGFR)-Modified Recurrent Glioblastoma (rGBM) | not yet recruiting | Phase 1 | 72 | Crimson Biopharm Inc.INDUSTRY | 0 | Aug 21, 2024 | clinicaltrials |
| NCT06556186 | Surgical and Pharmacological Efficacy of Knosp Grade 0-2 Prolactinoma | not yet recruiting | N/A | 600 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Aug 15, 2024 | clinicaltrials |
| NCT06524063 | Targeted Survivin DC Cell Injection for the Treatment of GBM | not yet recruiting | Phase 1 | 9 | Beijing Tricision Biotherapeutics IncINDUSTRY | 0 | Jul 29, 2024 | clinicaltrials |
| NCT06512298 | Plasticizer Exposure and Its Consequences on Health(PEACH) | not yet recruiting | — | 120 | Medical University of ViennaOTHER | 1 | Jul 24, 2024 | clinicaltrials |
| NCT06516471 | The Evolution of Neuroendoscopy Guided by Head-mounted Mixed Reality Technique Navigation System in Neurosurgery | not yet recruiting | N/A | 40 | Shanghai Zhongshan HospitalOTHER | 0 | Jul 24, 2024 | clinicaltrials |
| NCT06511323 | Evaluation of Brain Metastases Treated With Stereotactic Radiotherapy Using Dynamic [18F]FDG PET | not yet recruiting | N/A | 70 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sOTHER | 0 | Jul 19, 2024 | clinicaltrials |
| NCT06495580 | Optic Nerve Stimulation To Prevent Visual Deficits After Endoscopic Cranial Approaches | not yet recruiting | N/A | 20 | University of California, San FranciscoOTHER | 1 | Jul 12, 2024 | clinicaltrials |
| NCT06499636 | In Vitro Models From Pediatric Brain Tumors(PBTS23) | not yet recruiting | — | 100 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Jul 12, 2024 | clinicaltrials |
| NCT06485908 | Axitinib and Oral Metronomic Etoposide for Pediatric Children and AYA Refractory/Relapsing Medulloblastoma and Ependymoma(MEPENDAX) | not yet recruiting | Phase 1 / Phase 2 | 40 | Assistance Publique Hopitaux De MarseilleOTHER | 0 | Jul 3, 2024 | clinicaltrials |
| NCT06480721 | FET-PET-Guided Management of Pseudoprogression in Glioblastoma(FET-POPPING) | not yet recruiting | N/A | 144 | Veerle RuijtersOTHER | 1 | Jun 28, 2024 | clinicaltrials |
| NCT06477939 | Study of Adding or Not Liposomal Transcrocetin (L-TC) With Concomitant HypoFractionated Radiation ThErapy and TEmozolomide in Newly Diagnosed GLioblastoma (GBM) Patients(THREE-GLEES) | not yet recruiting | Phase 3 | 554 | Institut de cancérologie Strasbourg EuropeOTHER | 1 | Jun 27, 2024 | clinicaltrials |
| NCT06326853 | Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical Models | not yet recruiting | — | 200 | IRCCS San RaffaeleOTHER | 0 | Jun 11, 2024 | clinicaltrials |
| NCT06441045 | Double Dose of Third-generation EGFR-TKI Plus Intrathecal Pemetrexed Versus Double Dose of Third-generation EGFR-TKI in Patients With LM Progression Following the Treatment of Routine Dose of Third-generation EGFR-TKI | not yet recruiting | Phase 2 | 112 | Fujian Cancer HospitalOTHER_GOV | 1 | Jun 4, 2024 | clinicaltrials |
| NCT06396481 | Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma(CSAγδTBMG) | not yet recruiting | Early Phase 1 | 25 | Beijing Tiantan HospitalOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT06374888 | Nilatinib Maleate Tablets Combined With Capecitabine in the Treatment of HER2-positive Advanced Esophageal/Esophagogastric Junction/Gastric Adenocarcinoma With Brain Metastases | not yet recruiting | Phase 2 | 28 | Convalife (Shanghai) Co., Ltd.INDUSTRY | 0 | Apr 19, 2024 | clinicaltrials |
| NCT06368934 | Sub-lobectomy for IDH Wild-type and TERT Promoter Mutant Glioblastoma | not yet recruiting | N/A | 326 | Huashan HospitalOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT03763396 | Azoles Targeting Recurrent High Grade Gliomas | not yet recruiting | Early Phase 1 | 30 | University Health Network, TorontoOTHER | 1 | Mar 8, 2024 | clinicaltrials |
| NCT06218524 | The Effectiveness of HP and TMZ Synergism on Adult Recurrence GBM | not yet recruiting | Phase 2 | 200 | Southern Medical University, ChinaOTHER | 0 | Jan 23, 2024 | clinicaltrials |
| NCT06201351 | Study of Adaptive Radiotherapy for High-grade Glioma Based on Interfraction MRI | not yet recruiting | — | 60 | West China HospitalOTHER | 1 | Jan 11, 2024 | clinicaltrials |
| NCT06093165 | RE-irradiation of Diffuse MIdline Glioma paTients(REMIT) | not yet recruiting | N/A | 59 | Rigshospitalet, DenmarkOTHER | 0 | Oct 23, 2023 | clinicaltrials |
| NCT05540275 | Tislelizumab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for Bevacizumab Refractory Recurrent Glioblastoma | not yet recruiting | Phase 2 | 30 | Henan Provincial People's HospitalOTHER | 1 | Oct 6, 2023 | clinicaltrials |
| NCT06017063 | Coaching for Coping in Glioblastoma Patients and Caregivers and Its Association With Compliance to TTFields(COCOON) | not yet recruiting | N/A | 275 | University Hospital TuebingenOTHER | 0 | Aug 30, 2023 | clinicaltrials |
| NCT05917821 | New Antigens Against Glioblastoma(INAAG) | not yet recruiting | — | 120 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 0 | Jul 24, 2023 | clinicaltrials |
| NCT05842746 | Elemene Plus Stupp Protocol Versus Stupp Protocol Alone for Newly-diagnosed Glioblastoma | not yet recruiting | Phase 2 | 74 | Peking Union Medical College HospitalOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT05100641 | AV-GBM-1 vs Control as Adjunctive Therapy Following Surgery and RT/TMZ in Newly Diagnosed GBM | not yet recruiting | Phase 3 | 672 | Aivita Biomedical, Inc.INDUSTRY | 0 | Apr 10, 2023 | clinicaltrials |
| NCT05406947 | Establishment and Clinical Application of Risk Classification Model Based on Molecular Typing of Medulloblastoma in Children | not yet recruiting | — | 350 | Beijing Tiantan HospitalOTHER | 0 | Feb 8, 2023 | clinicaltrials |
| NCT05641220 | Biopsy Versus Resection in Elderly Glioblastoma Patients. A Prospective Cohort Study.(BIOPSY) | not yet recruiting | — | 325 | Erasmus Medical CenterOTHER | 1 | Dec 7, 2022 | clinicaltrials |
| NCT05502991 | Sintilimab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for ctDNA-level-relapse and Clinical-relapse Glioblastoma | not yet recruiting | Phase 2 | 60 | Henan Provincial People's HospitalOTHER | 1 | Sep 27, 2022 | clinicaltrials |
| NCT05532969 | Correlation Between Psychological Stress and Progression of Diffuse Astrocytoma Towards Secondary Glioma | not yet recruiting | — | 60 | Henan Provincial People's HospitalOTHER | 1 | Sep 27, 2022 | clinicaltrials |
| NCT05536986 | Correlation Between Psychological Stress and Progression of Newly Oligodendroglioma Towards Secondary Glioma | not yet recruiting | — | 60 | Henan Provincial People's HospitalOTHER | 0 | Sep 27, 2022 | clinicaltrials |
Data updated 22 days agoSource updated Mar 10, 2025source: clinicaltrials