Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,060 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01535430 | Assessment of Eloquent Function in Brain Tumor Patients | recruiting | — | 75 | University of NebraskaOTHER | 1 | Jan 13, 2026 | clinicaltrials |
| NCT07335315 | Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary Tumors | recruiting | — | 110 | Mayo ClinicOTHER | 1 | Jan 13, 2026 | clinicaltrials |
| NCT05465954 | Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma | recruiting | Phase 2 | 54 | Mayo ClinicOTHER | 1 | Jan 12, 2026 | clinicaltrials |
| NCT07332234 | Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies(EICON) | recruiting | — | 200 | Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș"OTHER | 1 | Jan 12, 2026 | clinicaltrials |
| NCT05083754 | Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma | recruiting | Phase 1 | 50 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jan 9, 2026 | clinicaltrials |
| NCT05106296 | Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer | recruiting | Phase 1 | 37 | Theodore S. JohnsonOTHER | 1 | Jan 9, 2026 | clinicaltrials |
| NCT05669820 | Antisecretory Factor Glioblastoma Phase 2(AFGB2) | recruiting | Phase 2 / Phase 3 | 300 | Peter SiesjöOTHER | 1 | Jan 9, 2026 | clinicaltrials |
| NCT06799481 | Virtual Home-based Exercise Intervention (RISE) to Improve Cancer-Related Cognitive Impairment and Gut Microbiome in Adolescent and Young Adult Brain Tumor Survivors | recruiting | N/A | 60 | Emory UniversityOTHER | 1 | Jan 9, 2026 | clinicaltrials |
| NCT07240662 | Vorasidenib in CNS WHO Grade 2 IDH-mutant Diffuse Glioma(VIOLETA) | recruiting | — | 150 | iOMEDICO AGINDUSTRY | 1 | Jan 9, 2026 | clinicaltrials |
| NCT02358187 | A Vaccine Trial for Low Grade Gliomas | recruiting | Phase 2 | 25 | James FelkerOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT07321353 | Survivors Journey+(SJ) | recruiting | N/A | 72 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT07323966 | Feasibility of Mask-Free Radiotherapy for Brain Tumor Patients(MASKLESS) | recruiting | N/A | 20 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT06584123 | Molecular Pituitary Imaging Using 18F-FET PET(FET-pit-PET) | recruiting | N/A | 20 | University of CambridgeOTHER | 1 | Jan 6, 2026 | clinicaltrials |
| NCT03267459 | Can Pretreatment MRI be Used to Predict Intra-arterial Chemotherapy Response in Retinoblastoma?(PREDIR) | recruiting | — | 60 | Fondation Ophtalmologique Adolphe de RothschildNETWORK | 1 | Jan 5, 2026 | clinicaltrials |
| NCT05049148 | Platelets Activation in Brain Neoplasms(Platon) | recruiting | N/A | 50 | Fondation Ophtalmologique Adolphe de RothschildNETWORK | 1 | Jan 5, 2026 | clinicaltrials |
| NCT05688683 | Brain Representation of Acquisition in Humans of Motor-Sensory Skills(BRAHMS) | recruiting | — | 50 | Fondation Ophtalmologique Adolphe de RothschildNETWORK | 1 | Jan 5, 2026 | clinicaltrials |
| NCT06717295 | The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling(CCANED-CIPHER) | recruiting | — | 6,000 | Javier ToledoINDUSTRY | 3 | Jan 2, 2026 | clinicaltrials |
| NCT06829173 | Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas | recruiting | Early Phase 1 | 39 | NYU Langone HealthOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT07093814 | A Study of VRT106 for Injection in Patients With Recurrent/Progressive Glioblastoma | recruiting | Phase 1 / Phase 2 | 42 | Guangzhou Virotech Pharmaceutical Co., Ltd.INDUSTRY | 1 | Jan 2, 2026 | clinicaltrials |
| NCT06645808 | PET-imaging of Two Vartumabs in Patients With Solid Tumors(VARTUTRACE) | recruiting | Early Phase 1 | 32 | Var2 PharmaceuticalsINDUSTRY | 1 | Dec 29, 2025 | clinicaltrials |
| NCT07306299 | A Phase I Clinical Trial of a mRNA Vaccine for Recurrent or Progressive High-grade Glioma | recruiting | Phase 1 | 10 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 29, 2025 | clinicaltrials |
| NCT05423210 | Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme | recruiting | Early Phase 1 | 12 | Stony Brook UniversityOTHER | 1 | Dec 22, 2025 | clinicaltrials |
| NCT06468176 | Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma(FREEDOME) | recruiting | N/A | 187 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT07145047 | Clinical Study of Oncolytic Virus in Glioblastoma | recruiting | Phase 1 / Phase 2 | 20 | Mianyang Central HospitalOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT04541082 | Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms | recruiting | Phase 1 | 102 | Jazz PharmaceuticalsINDUSTRY | 1 | Dec 18, 2025 | clinicaltrials |
| NCT04543201 | Telehealth Visits to Discuss Advanced Directives for Patients Newly Diagnosed With High Grade Glioma | recruiting | N/A | 50 | University of RochesterOTHER | 1 | Dec 18, 2025 | clinicaltrials |
| NCT04852354 | Tissue Collection for Drug Screening and Bioanalysis | recruiting | — | 500 | Weill Medical College of Cornell UniversityOTHER | 1 | Dec 17, 2025 | clinicaltrials |
| NCT05259605 | Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification | recruiting | — | 1,650 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 12 | Dec 17, 2025 | clinicaltrials |
| NCT05976490 | NeuroPathways Intervention for Brain Tumor Patients | recruiting | N/A | 50 | Massachusetts General HospitalOTHER | 1 | Dec 17, 2025 | clinicaltrials |
| NCT07062627 | Anbalcabtagene Autoleucel in Relapsed/Refractory CNS Lymphoma | recruiting | Phase 2 | 12 | Hyungwoo ChoOTHER | 1 | Dec 17, 2025 | clinicaltrials |
| NCT05686798 | Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma. | recruiting | Phase 1 | 18 | Henry Ford Health SystemOTHER | 1 | Dec 16, 2025 | clinicaltrials |
| NCT06054295 | Somatic Mosaicism in Twins Discordant for Childhood Cancer | recruiting | — | 50 | Children's Oncology GroupNETWORK | 1 | Dec 16, 2025 | clinicaltrials |
| NCT06898684 | Medulloblastoma Online Video-based Exercise Pilot Study(MOVE) | recruiting | N/A | 15 | Aron OnerupOTHER_GOV | 2 | Dec 16, 2025 | clinicaltrials |
| NCT07286903 | Fluorescence Enhanced Stereotactic Surgery (FESS)(FESS) | recruiting | — | 20 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo BestaOTHER | 1 | Dec 16, 2025 | clinicaltrials |
| NCT07286929 | Evaluation of the Variation Over Time of Visuospatial Deficit in Patients With Parietal Lobe Glioma(neGLIO) | recruiting | — | 40 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo BestaOTHER | 1 | Dec 16, 2025 | clinicaltrials |
| NCT05956821 | Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age | recruiting | Phase 1 / Phase 2 | 20 | University of MiamiOTHER | 1 | Dec 8, 2025 | clinicaltrials |
| NCT07077616 | Clinical Study for the Safety and Therapeutic Efficacy of the AI-QMMM Designed TamavaqTM Personalised Vaccine in Patients With Newly Diagnosed Glioma.(TAMAVAQTM) | recruiting | Early Phase 1 | 29 | Biogenea Pharmaceuticals Ltd.INDUSTRY | 1 | Dec 8, 2025 | clinicaltrials |
| NCT02417324 | International HIT-MED Registry (I-HIT-MED) | recruiting | — | 500 | Universitätsklinikum Hamburg-EppendorfOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT05553041 | 18F-Fluciclovine PET-MRI in High-grade Glioma | recruiting | Early Phase 1 | 30 | Children's Hospital of PhiladelphiaOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT07263711 | Prospective Real-World Study of Pathology AI for Glioma Molecular Prediction | recruiting | — | 2,000 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT07264569 | Evaluate the Safety, Tolerability, Biodistribution Characteristics and Preliminary Efficacy of BioTTT001 | recruiting | Phase 1 / Phase 2 | 42 | Henan Cancer HospitalOTHER_GOV | 1 | Dec 4, 2025 | clinicaltrials |
| NCT05990244 | Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion | recruiting | N/A | 100 | Shengjing HospitalOTHER | 1 | Dec 2, 2025 | clinicaltrials |
| NCT06964815 | Silibinin in Association With Concomitant Chemoradiotherapy and Maintenance Temozolomide in STAT3 Positive IDH Wild-type, Newly Diagnosed Glioblastoma Patients(STRONG) | recruiting | N/A | 110 | Istituto Oncologico Veneto IRCCSOTHER | 1 | Dec 2, 2025 | clinicaltrials |
| NCT07175077 | 7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI) | recruiting | — | 20 | University of Missouri-ColumbiaOTHER | 1 | Dec 2, 2025 | clinicaltrials |
| NCT05554302 | Characterization of 18F-Fluciclovine PET Amino Acid Radiotracer in Resected Brain Metastasis(CONCORDANT) | recruiting | Phase 2 | 20 | Baptist Health South FloridaOTHER | 1 | Dec 1, 2025 | clinicaltrials |
| NCT04681417 | Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategies and Visual Outcome(RETINO 2018) | recruiting | Phase 2 / Phase 3 | 225 | Institut CurieOTHER | 1 | Nov 28, 2025 | clinicaltrials |
| NCT05768178 | DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.(DETERMINE) | recruiting | Phase 2 / Phase 3 | 30 | Cancer Research UKOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT05770544 | DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers.(DETERMINE) | recruiting | Phase 2 / Phase 3 | 30 | Cancer Research UKOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT06988475 | DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations(DETERMINE) | recruiting | Phase 2 / Phase 3 | 30 | Cancer Research UKOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT02914067 | Cognitive Biomarkers in Pediatric Brain Tumor Patients | recruiting | N/A | 200 | Washington University School of MedicineOTHER | 1 | Nov 21, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Jan 13, 2026source: clinicaltrials