Clinical trial · Observational
7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)
NCT07175077CI-TRIAL-00098208recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Comparison of a 7t MRI to standard of care 1.5t/3t MRI scans to determine if earlier detection of brain metastases are possible on a 7t.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Metastases | Brain Neoplasm | PROBABILISTIC | 0.70 |
| Small-cell Lung Cancer | Lung Small Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 7t MRI | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- 7t MRI Brain Metastases Detection
- timeFrame
- 3, 6, 9, 12 months after 7T MRI
- description
- Comparison of 7t MRI to 1.5t/3t to determine if the 7t MRI was able to detect metastases prior to a 1.5t/3t MRI
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient must have a histologically confirmed diagnosis of small-cell lung cancer (SCLC). • Patient must have an MRI of the brain, performed within 4 weeks prior to consent, documenting no evidence of brain metastases or leptomeningeal disease. * Patient also must not have a history of brain metastases or leptomeningeal disease. * Patient must refuse PCI and agree to surveillance with brain MRI scans (1.5T/3T). * Patient must be ≥ 18 years of age. * Patient must have ECOG Performance Status of 0-2 * Patients must be able to tolerate the 7T MRI Exclusion Criteria: * Patient must not have a contraindication to an MRI, such as implanted metal devices or foreign bodies. * Patient must not have a contraindication to gadolinium contrast administration during MR imaging. * Patient must not have other metastatic malignancies requiring current active treatment. * Pregnant patients are excluded. Pregnancy status will be confirmed verbally.
References
Publications (0)
Data not yet available
No reference posted for this study.