Clinical trial · Observational
Evaluation of the Variation Over Time of Visuospatial Deficit in Patients With Parietal Lobe Glioma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of modern neurooncological surgery is to obtain maximum tumor resection while preserving neurological function. Parietal lobe gliomas often cause attention deficits (hemineglect) that are difficult to differentiate from other deficits. This study aims to evaluate the extent and variation over time of visuo-spatial deficits in patients undergoing surgical removal of parietal lobe gliomas. This will help characterize the cognitive profile of these patients to identify personalized treatment and rehabilitation paths.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Glioma | Glioma | ONTOLOGY_EXACT | 0.98 |
| Parietal Lobe Glioma | — | UNRESOLVED | — |
| Unilateral Spatial Neglect (USN) | — | UNRESOLVED | — |
| Visuspatial Deficit | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Change in Visuospatial Deficit Prevalence
- timeFrame
- Baseline (pre-surgery), 3-4 months post-surgery, 6 months post-surgery.
- description
- Prevalence of patients with a score below the cut-off in specific neuropsychological tests for visuo-spatial aspects (Line Bisection, Bell/Letter Cancellation, Apple Cancellation, Fluff Test) and the extent of change compared to baseline.
Secondary outcomes (4)
- measure
- Association with Radiological Data
- timeFrame
- Up to 6 months post-surgery
- description
- Correlation between visuo-spatial deficit scores and MRI data (FLAIR volume, T1 contrast, necrosis, localization).
- measure
- Association with Clinical-Demographic Data
- timeFrame
- Up to 6 months post-surgery.
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients \>18 years old * Patients must understand the Italian Language * Patients with suspected parietal lobe glioma Exclusion Criteria: * Tumor site other than parietal lobe. * Patients who cannot undergo surgical resection (stereotactic/open biopsy). * Patients who received a previous chemotherapy and/or radiotherapy treatment. * Patients with a history of intracranial mass lesion or traumatic brain injury. * Patients with a history of other CNS diseases (e.g., stroke, metastasis). * Patients with diagnosis of neurodegenerative disease (i.e. Alzheimer's Disease, Frontotemporal Dementia, Parkinson's Disease, Lewy Body Dementia, Amyotrophic Lateral Sclerosis).
References
Publications (0)
Data not yet available