Cancer Family
Breast Neoplasm
CI-CAN-00000007Explore in graph →
Non-malignant2,894 active trials43 approved drugs310 evidence items
- NCIt
- C2910
- OncoTree
- BNNOS
- MeSH
- D000069584
- MeSH
- D001943
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Cancer Family
CI-CAN-00000007Explore in graph →
Genomics
33 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
186 cases with simple somatic mutation data · 187 cases total · 2026-01-05 · mapped to Invasive Breast Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 | Ssm | 89 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 186 |
| 47.8% |
| cbioportal |
| 2 | PIK3CA | Ssm | 53 | 186 | 28.5% | cbioportal |
| 4 | TTN | Ssm | 23 | 186 | 12.4% | cbioportal |
| 3 | GATA3 | Ssm | 23 | 186 | 12.4% | cbioportal |
| 5 | MUC16 | Ssm | 12 | 186 | 6.5% | cbioportal |
| 7 | MAP3K1 | Ssm | 9 | 186 | 4.8% | cbioportal |
| 6 | CSMD3 | Ssm | 9 | 186 | 4.8% | cbioportal |
| 8 | MAML3 | Ssm | 8 | 186 | 4.3% | cbioportal |
| 11 | KMT2C | Ssm | 7 | 186 | 3.8% | cbioportal |
| 15 | SYNE1 | Ssm | 7 | 186 | 3.8% | cbioportal |
| 10 | ARID1A | Ssm | 7 | 186 | 3.8% | cbioportal |
| 9 | APOB | Ssm | 7 | 186 | 3.8% | cbioportal |
| 14 | NF1 | Ssm | 7 | 186 | 3.8% | cbioportal |
| 13 | NEB | Ssm | 7 | 186 | 3.8% | cbioportal |
| 16 | UBR4 | Ssm | 7 | 186 | 3.8% | cbioportal |
| 12 | MUC4 | Ssm | 7 | 186 | 3.8% | cbioportal |
| 18 | NEFH | Ssm | 6 | 186 | 3.2% | cbioportal |
| 22 | ZNF536 | Ssm | 6 | 186 | 3.2% | cbioportal |
| 19 | PKHD1 | Ssm | 6 | 186 | 3.2% | cbioportal |
| 17 | LRP1B | Ssm | 6 | 186 | 3.2% | cbioportal |
| 20 | PTEN | Ssm | 6 | 186 | 3.2% | cbioportal |
| 21 | USH2A | Ssm | 6 | 186 | 3.2% | cbioportal |
| 40 | NPAS4 | Ssm | 5 | 186 | 2.7% | cbioportal |
| 27 | BIRC6 | Ssm | 5 | 186 | 2.7% | cbioportal |
| 39 | NES | Ssm | 5 | 186 | 2.7% | cbioportal |
| 38 | MXRA5 | Ssm | 5 | 186 | 2.7% | cbioportal |
| 24 | AKT1 | Ssm | 5 | 186 | 2.7% | cbioportal |
| 28 | CBFB | Ssm | 5 | 186 | 2.7% | cbioportal |
| 41 | OBSCN | Ssm | 5 | 186 | 2.7% | cbioportal |
| 36 | HUWE1 | Ssm | 5 | 186 | 2.7% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05