Cancer Family
Breast Neoplasm
CI-CAN-00000007Explore in graph →
Non-malignant2,893 active trials43 approved drugs310 evidence items
- NCIt
- C2910
- OncoTree
- BNNOS
- MeSH
- D000069584
- MeSH
- D001943
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Cancer Family
CI-CAN-00000007Explore in graph →
Genomics
33 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
237 cases with simple somatic mutation data · 237 cases total · 2026-01-05 · mapped to Invasive Breast Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | PIK3CA | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 76 |
| 237 |
| 32.1% |
| cbioportal |
| 2 | TP53 | Ssm | 76 | 237 | 32.1% | cbioportal |
| 3 | TTN | Ssm | 51 | 237 | 21.5% | cbioportal |
| 4 | CDH1 | Ssm | 34 | 237 | 14.3% | cbioportal |
| 5 | HMCN1 | Ssm | 24 | 237 | 10.1% | cbioportal |
| 6 | GATA3 | Ssm | 23 | 237 | 9.7% | cbioportal |
| 7 | MUC16 | Ssm | 21 | 237 | 8.9% | cbioportal |
| 8 | PTEN | Ssm | 19 | 237 | 8% | cbioportal |
| 9 | KMT2C | Ssm | 17 | 237 | 7.2% | cbioportal |
| 11 | DMD | Ssm | 16 | 237 | 6.8% | cbioportal |
| 10 | CSMD3 | Ssm | 16 | 237 | 6.8% | cbioportal |
| 13 | USH2A | Ssm | 15 | 237 | 6.3% | cbioportal |
| 12 | DNAH5 | Ssm | 15 | 237 | 6.3% | cbioportal |
| 14 | CSMD1 | Ssm | 14 | 237 | 5.9% | cbioportal |
| 16 | STAB2 | Ssm | 14 | 237 | 5.9% | cbioportal |
| 15 | HUWE1 | Ssm | 14 | 237 | 5.9% | cbioportal |
| 17 | TENM2 | Ssm | 14 | 237 | 5.9% | cbioportal |
| 18 | BLTP1 | Ssm | 13 | 237 | 5.5% | cbioportal |
| 19 | MUC5B | Ssm | 13 | 237 | 5.5% | cbioportal |
| 21 | DST | Ssm | 12 | 237 | 5.1% | cbioportal |
| 20 | ARID1A | Ssm | 12 | 237 | 5.1% | cbioportal |
| 23 | SPTA1 | Ssm | 12 | 237 | 5.1% | cbioportal |
| 24 | SYNE1 | Ssm | 12 | 237 | 5.1% | cbioportal |
| 25 | TBX3 | Ssm | 12 | 237 | 5.1% | cbioportal |
| 22 | FMN2 | Ssm | 12 | 237 | 5.1% | cbioportal |
| 31 | RNF213 | Ssm | 11 | 237 | 4.6% | cbioportal |
| 29 | MYT1L | Ssm | 11 | 237 | 4.6% | cbioportal |
| 28 | KDM6B | Ssm | 11 | 237 | 4.6% | cbioportal |
| 35 | TG | Ssm | 11 | 237 | 4.6% | cbioportal |
| 34 | TCHH | Ssm | 11 | 237 | 4.6% | cbioportal |
Data updated 21 days agoSource updated 2026-01-05