Molecular Subtype
ALK-Positive Lung Non-Small Cell Carcinoma
CI-CAN-00007197Explore in graph →
10 active trials1 approved drugs
- NCIt
- C215346
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Molecular Subtype
CI-CAN-00007197Explore in graph →
Data completeness3 / 7 dimensions
Computed from entity_counters.completeness · refreshed after each connector run
Definition
A lung non-small cell carcinoma (NSCLC) characterized by the presence of rearrangements of the ALK gene that lead to activation of ALK kinase and ALK driven tumor formation. These rearrangements were initially identified as EML4-ALK fusions, but a variety of other ALK gene fusions were subsequently identified. Approximately 5% of patients with NSCLC carry ALK rearrangements and are highly sensitive to treatment with ALK inhibitors.
Data updated 22 days agoSource updated 26.08e
Taxonomy
Several hierarchies coexist; edges are listed per hierarchy type with their source.
Parents
Children (0)
Leaf node — no children.
Anatomy
Data updated 18 hours agoSource updated unknowncounters aggregate over descendants
Names
CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.
Key figures
Each figure carries its unit, period and source; ranks link to "Why this rank?".
Data updated 18 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants