Histology
Adenocarcinoma
CI-CAN-00000403Explore in graph →
2,751 active trials43 approved drugs423 evidence items
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Histology
CI-CAN-00000403Explore in graph →
Genomics
162 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
504 cases with simple somatic mutation data · 504 cases total · 2026-01-13 · mapped to Prostate Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 166 |
| 504 |
| 32.9% |
| cbioportal |
| 2 | FOXA1 | Ssm | 58 | 504 | 11.5% | cbioportal |
| 3 | SPOP | Ssm | 47 | 504 | 9.3% | cbioportal |
| 4 | APC | Ssm | 40 | 504 | 7.9% | cbioportal |
| 5 | KMT2C | Ssm | 34 | 504 | 6.7% | cbioportal |
| 6 | PTEN | Ssm | 28 | 504 | 5.6% | cbioportal |
| 7 | CDK12 | Ssm | 27 | 504 | 5.4% | cbioportal |
| 9 | KMT2D | Ssm | 25 | 504 | 5% | cbioportal |
| 8 | AR | Ssm | 25 | 504 | 5% | cbioportal |
| 10 | BRCA2 | Ssm | 24 | 504 | 4.8% | cbioportal |
| 11 | SPEN | Ssm | 21 | 504 | 4.2% | cbioportal |
| 12 | GRIN2A | Ssm | 19 | 504 | 3.8% | cbioportal |
| 13 | ATM | Ssm | 18 | 504 | 3.6% | cbioportal |
| 15 | PIK3CA | Ssm | 17 | 504 | 3.4% | cbioportal |
| 14 | CTNNB1 | Ssm | 17 | 504 | 3.4% | cbioportal |
| 16 | JAK1 | Ssm | 15 | 504 | 3% | cbioportal |
| 30 | ZFHX3 | Ssm | 10 | 345 | 2.9% | cbioportal |
| 27 | MGA | Ssm | 10 | 345 | 2.9% | cbioportal |
| 18 | RB1 | Ssm | 14 | 504 | 2.8% | cbioportal |
| 17 | FAT1 | Ssm | 14 | 504 | 2.8% | cbioportal |
| 19 | KMT2A | Ssm | 12 | 504 | 2.4% | cbioportal |
| 20 | MED12 | Ssm | 12 | 504 | 2.4% | cbioportal |
| 21 | NCOR1 | Ssm | 12 | 504 | 2.4% | cbioportal |
| 25 | PTPRS | Ssm | 11 | 504 | 2.2% | cbioportal |
| 23 | KDM6A | Ssm | 11 | 504 | 2.2% | cbioportal |
| 22 | ASXL1 | Ssm | 11 | 504 | 2.2% | cbioportal |
| 24 | NOTCH1 | Ssm | 11 | 504 | 2.2% | cbioportal |
| 28 | NSD1 | Ssm | 10 | 504 | 2% | cbioportal |
| 26 | BRAF | Ssm | 10 | 504 | 2% | cbioportal |
| 29 | PIK3R1 | Ssm | 10 | 504 | 2% | cbioportal |
Data updated 22 days agoSource updated 2026-01-13