Loading clinical trials…
Loading clinical trials…
Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
625 stopped studies mapped to Malignant Urinary System Neoplasm and descendants · 88% state a reason
Over the 625 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02479178 | A Study of BIND-014 in Patients With Urothelial Carcinoma, Cholangiocarcinoma, Cervical…(iNSITE2) | Phase 2 | terminated | Jun 24, 2015 | BIND Therapeutics | not stated | Not stated |
| NCT00556205 | Bevacizumab With or Without Sunitinib in Sunitinib-Refractory Renal Cell Carcinoma | Phase 2 | withdrawn | Nov 9, 2007 | Massachusetts General Hospital | Toxicity of combination from other trials | Safety / toxicity |
| NCT00831480 | Everolimus (RAD001) For Advanced Renal Cell Carcinoma (RCC) Before Kidney Removal | Phase 2 | terminated | Jan 29, 2009 | Linda C. Higgins | Difficulty in accrual and by the order of the cancer center. | Enrollment / accrual |
| NCT00440973 | Safety Study of Specific Tumor Target Drug Plus Immune System Therapy in Patients With… | Phase 2 | terminated | Feb 27, 2007 | The Methodist Hospital Research Institute | contract issues | Other (stated, no rule matched) |
| NCT00522249 | Study of Pegylated Alfa Interferon, Sunitinib and Tarceva in Patients With Metastatic RCC | Phase 1 / Phase 2 | terminated | Aug 29, 2007 | The Methodist Hospital Research Institute | PI decision | Other (stated, no rule matched) |
| NCT02307474 | A Pilot Study of SBRT With Adjuvant Pazopanib for Renal Cell Cancer | N/A | withdrawn | Dec 4, 2014 | Case Comprehensive Cancer Center | Funding Unavailable | Funding |
| NCT01916109 | Study of Gemcitabine, Carboplatin, and Panitumumab (GCaP) as Neoadjuvant Chemotherapy in… | Phase 2 | terminated | Aug 5, 2013 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT01888042 | Assessing Everolimus in Fist Line Treatment on Patients With Metastatic Kidney Cancer(POORTOR) | Phase 2 | terminated | Jun 27, 2013 | Gustave Roussy, Cancer Campus, Grand Paris | not stated | Not stated |
| NCT01762033 | A Phase 2 Study of ASONEP™ to Treat Unresectable and Refractory Renal Cell Carcinoma | Phase 2 | terminated | Jan 7, 2013 | Lpath, Inc. | not stated | Not stated |
| NCT01771003 | Remote Ischemia Pre-Conditioning in Patients Undergoing Partial Nephrectomy | N/A | terminated | Jan 18, 2013 | University Health Network, Toronto | not stated | Not stated |
| NCT00480935 | A Study of Neoadjuvant Sutent for Patients With Renal Cell Carcinoma | Phase 2 | terminated | May 31, 2007 | University Health Network, Toronto | poor recruitment | Enrollment / accrual |
| NCT01663285 | Clinical Trial Of Neoadjuvant Chemotherapy (NAC)In Upper Tract Urothelial Carcinoma (UTUC) | Phase 2 | terminated | Aug 13, 2012 | University of Michigan Rogel Cancer Center | Low study participant enrollment. | Enrollment / accrual |
| NCT00913913 | Bevacizumab, Autologous Tumor/DC Vaccine, IL-2 and IFNα-2b in Metastatic Renal Cell… | Phase 2 | terminated | Jun 4, 2009 | Dartmouth-Hitchcock Medical Center | low accrual not allowing site to meeting statistical endpoints | Enrollment / accrual |
| NCT01977586 | Functional Imaging in the Assessment of mRCC Response to Sunitinib | N/A | withdrawn | Nov 6, 2013 | Imperial College Healthcare NHS Trust | Difficulty in recruiting suitable patients at centre | Enrollment / accrual |
| NCT00974818 | Mitomycin C Versus Bacillus Calmette-Guerin in the Intravesical Treatment of… | Phase 3 | terminated | Sep 10, 2009 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT00714948 | Gemcitabine and Split-dose Cisplatin (GC) Plus Sorafenib in Chemotherapy-naïve Patients… | Phase 2 | terminated | Jul 14, 2008 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT00006126 | Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Small Cell… | Phase 1 | withdrawn | Mar 8, 2004 | Northwestern University | Unable to accrue subjects. | Enrollment / accrual |
| NCT00479089 | Iressa and Taxotere Study in Patients With Metastatic Urothelial Cancer | Phase 2 | terminated | May 25, 2007 | M.D. Anderson Cancer Center | Study halted due to drug sponsor decision to not continue. | Sponsor / business decision |
| NCT00704938 | Gene-Modified Lymphocytes, High-Dose Aldesleukin, and Vaccine Therapy in Treating… | Phase 2 | terminated | Jun 25, 2008 | National Institutes of Health Clinical Center (CC) | Terminated due to withdrawal of support from our collaborator. | Other (stated, no rule matched) |
| NCT00747305 | Sunitinib Before and After Surgery in Treating Patients With Metastatic Kidney Cancer… | Phase 1 | terminated | Sep 5, 2008 | Harry Drabkin | Study terminated early due to low accrual. | Enrollment / accrual |
| NCT00635726 | Methotrexate, Vinblastine, Doxorubicin and Cisplatin (MVAC) Followed by Gemcitabine Plus… | Phase 2 | terminated | Mar 14, 2008 | Hellenic Oncology Research Group | Due to poor accrual | Enrollment / accrual |
| NCT01342627 | Sorafenib in Elderly Patients With Metastatic Renal Cell Carcinoma(SERCC) | Phase 2 | terminated | Apr 27, 2011 | Centro di Riferimento Oncologico - Aviano | low enrollment rate | Enrollment / accrual |
| NCT00908739 | Studying Tumor Tissue Samples From Patients Who Have Undergone Surgery for Localized… | — | withdrawn | May 27, 2009 | Case Comprehensive Cancer Center | PI left | Investigator |
| NCT01100242 | Velcade and Sorafenib in Unresected or Metastatic Renal Cell Carcinoma | Phase 2 | terminated | Apr 8, 2010 | New Mexico Cancer Research Alliance | Low accrual | Enrollment / accrual |
| NCT00995488 | Trial of Combination ABI-007, Carboplatin, and Gemcitabine for First Line Treatment of… | Phase 2 | terminated | Oct 15, 2009 | University of Michigan Rogel Cancer Center | Terminated prematurely due to low accrual. | Enrollment / accrual |
| NCT01071928 | Second-Line Docetaxel + ASA404 for Advanced Urothelial Carcinoma | Phase 2 | withdrawn | Feb 19, 2010 | Hoosier Cancer Research Network | Lack of efficacy of experimental treatment | Efficacy / futility |
| NCT00574483 | Treatment of Advanced Renal Cell Carcinoma With Quinacrine | Phase 2 | withdrawn | Dec 17, 2007 | Cleveland BioLabs | reevaluation of compound development | Other (stated, no rule matched) |
| NCT00176280 | Randomized Phase 2 Trial of Pre-chemotherapy Leukine vs. Leukine-Dexamethasone in… | Phase 2 | withdrawn | Sep 15, 2005 | University of Kentucky | Slow accrual | Enrollment / accrual |
| NCT00601926 | Bevacizumab in Treating Patients With Unresectable or Metastatic Kidney Cancer | Phase 2 | terminated | Jan 28, 2008 | Paul Monk | Poor patient accrual. Attempts to open at other sites unsuccessful. | Enrollment / accrual |
| NCT01314664 | A Prospective Registry to Assess the Effectiveness and Local Tolerability of Intravesical… | — | terminated | Mar 14, 2011 | Endo USA Inc., a Keenova Therapeutics Company | Business decision, not safety related | Safety / toxicity |
| NCT00589550 | PEG-Interferon Alfa-2b and Sorafenib in Treating Patients With Unresectable or Metastatic… | Phase 1 | terminated | Jan 9, 2008 | Thomas Olencki | low accrual | Enrollment / accrual |
| NCT01374789 | PURO Panitumumab in Combination With Gemcitabine/Cisplatin in Advanced Urothelial Cancer(PURO) | Phase 2 | terminated | Jun 16, 2011 | WiSP Wissenschaftlicher Service Pharma GmbH | The study was terminated due to insufficient recruitment. | Enrollment / accrual |
| NCT01507740 | Profile of Soluble and Cellular Biomarkers and of Functional Imaging During… | — | terminated | Jan 11, 2012 | Medical University Innsbruck | Study was stopped 04.10.2014 prematurly after recruitment of HCC and RCC patients. NSCLC (2 of 10… | Enrollment / accrual |
| NCT00785694 | Recurrence of Bladder Cancer After Transurethral Resection With Hexvix | Phase 4 | withdrawn | Nov 5, 2008 | GE Healthcare | Rejected ethics approval in UK and Holland | Other (stated, no rule matched) |
| NCT00930345 | Biological, Pathological and Imagery Markers in the First-line Treatment of Metastatic…(PREINSUT) | Phase 4 | terminated | Jun 30, 2009 | Assistance Publique - Hôpitaux de Paris | not stated | Not stated |
| NCT01547676 | Clamped or Unclamped Surgery in Treating Patients With Kidney Cancer | N/A | terminated | Mar 8, 2012 | University of Southern California | P.I. decided to terminate study due to multiple unresolved issues | Other (stated, no rule matched) |
| NCT00933374 | Trial to Evaluate Paclitaxel Plus RAD001 in Urothelial Carcinoma(RAD001) | Phase 2 | terminated | Jul 7, 2009 | Heinrich-Heine University, Duesseldorf | delayed recruitment | Enrollment / accrual |
| NCT00918008 | A 12-Gene Blood-Based Signature for Detecting Metastatic Bladder Cancer | — | terminated | Jun 11, 2009 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT01720693 | Novel Controlled Hypo-Perfusion Technique in Partial Nephrectomy | Phase 2 | terminated | Nov 2, 2012 | University Health Network, Toronto | Low accrual | Enrollment / accrual |
| NCT01353794 | Study to Observe Safety and Efficacy of Nexavar in Treatment of Kidney Cancer(POWER-NEXT) | — | withdrawn | May 16, 2011 | Bayer | not stated | Not stated |
| NCT00352859 | Phase IV Randomization to On-Going Treatment to Evaluate Sustained Sorafenib | Phase 4 | terminated | Jul 17, 2006 | Bayer | not stated | Not stated |
| NCT00072137 | Neoadjuvant Intravesical Vaccine Therapy in Treating Patients With Bladder Carcinoma Who… | Phase 1 | terminated | Nov 6, 2003 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00622479 | Mechanistic Evaluation on Sorafenib Induced Hypophosphatemia. | Phase 1 | terminated | Feb 25, 2008 | Bayer | not stated | Not stated |
| NCT00624962 | Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid… | N/A | withdrawn | Feb 28, 2008 | Vanderbilt University | no participants enrolled | Enrollment / accrual |
| NCT00678288 | A Study to Assess Sorafenib Alone and in Combination With Low-Dose Interferon Following… | Phase 2 | terminated | May 15, 2008 | Bayer | not stated | Not stated |
| NCT00393796 | Trial of Maintenance SUO11248 Versus Placebo Post Chemotherapy for Patients With Advanced… | Phase 2 | terminated | Oct 30, 2006 | University of Michigan Rogel Cancer Center | Low accrual | Enrollment / accrual |
| NCT01486550 | Hydroxyethyl Starch and Renal Function After Laparoscopic Nephrectomy(VONE) | Phase 4 | terminated | Dec 6, 2011 | Regional Hospital Holstebro | Lack of patient enrollment | Enrollment / accrual |
| NCT00384891 | Hyperthermia Treatment in Conjunction With Mitomycin C Versus Bacillus Calmette-Guérin… | Phase 3 | terminated | Oct 6, 2006 | Medical Enterprises Europe B.V. | slow accrual | Enrollment / accrual |
| NCT02013765 | A Study of Herceptin (Trastuzumab) Monotherapy in Patients With Metastatic Urothelial… | Phase 2 | terminated | Dec 17, 2013 | Hoffmann-La Roche | Trial was terminated prematurely because of recruitment difficulties. | Enrollment / accrual |
| NCT01284205 | First Line Comparative Study of EN3348 (MCC) vs BCG in NMIBC | Phase 3 | withdrawn | Jan 26, 2011 | Bioniche Life Sciences Inc. | This indication is not being pursued at this point in time. | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Apr 14, 2016source: clinicaltrials