Clinical trial · Interventional
Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid Tumors
Pilot Study of Early Enteral Tube Feedings in Children Receiving Chemotherapy for Newly Diagnosed AML/MDS and High Risk Solid Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): no participants enrolled
Summary
Brief summary (as posted)
RATIONALE: Tubefeeding may help maintain good nutrition and lessen weight loss in younger patients receiving chemotherapy for cancer. PURPOSE: This clinical trial is studying how well tube feedings work in younger patients receiving chemotherapy for newly diagnosed acute myeloid leukemia, myelodysplastic syndrome, or high-risk solid tumors.
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain and Central Nervous System Tumors | — | UNRESOLVED | — |
| Kidney Cancer | Malignant Kidney Neoplasm | CURATED_EXACT | 0.92 |
| Leukemia | Leukemia | ONTOLOGY_EXACT | 0.90 |
| Liver Cancer | Malignant Liver Neoplasm | CURATED_EXACT | 0.92 |
| Neuroblastoma | Neuroblastoma | ONTOLOGY_EXACT | 0.90 |
| Sarcoma | Sarcoma | ONTOLOGY_EXACT | 0.98 |
| Solid Tumor | Solid Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| nutritional intervention | Dietary Supplement | — | UNRESOLVED |
| therapeutic nutritional supplementation | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Correlative/Supportive Care
- interventionNames
- Dietary Supplement: nutritional intervention
- Dietary Supplement: therapeutic nutritional supplementation
Primary outcomes (1)
- measure
- Successful administration of enteral feedings via a nasogastric tube for 50% or more of the total nutritional-support days
- timeFrame
- 50% or more of the total nutritional support days.
Secondary outcomes (9)
- measure
- Number of patients accepting early insertion of enteral feeding tube for an approximate twelve week period
- timeFrame
- twelve weeks
- measure
- Number of times tubes replaced and number of subjects refusing replacement
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Year
- Maximum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria:
* Newly confirmed diagnosis of 1 of the following:
* Acute myeloid leukemia
* Myelodysplastic syndromes
* Sarcoma
* Any other stage IV solid tumor including:
* Wilms
* Neuroblastoma
* Hepatoblastoma
* Any primary cancer of the central nervous system including:
* Cerebellar astrocytoma
* Medulloblastoma
* Ependymoma
* Spine tumors
Exclusion Criteria:
* No contraindication to enteral tube feeding including, but not limited to, any of the following:
* Gastrointestinal tract dysfunction (i.e., ileus, peritonitis, obstruction)
* Active sinusitis (can be waived for patients with gastrostomy tubes)
* Obstructive tumor in the nasopharynx
PRIOR CONCURRENT THERAPY:
* No prior hematopoietic stem cell transplant
* All clinically indicated medications are permitted during the course of the study
* No other concurrent nutritional supplementsReferences
Publications (0)
Data not yet available