Clinical trial · Interventional
Remote Ischemia Pre-Conditioning in Patients Undergoing Partial Nephrectomy
The Effect of Remote Ischemic Preconditioning in Partial Nephrectomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Partial Nephrectomy has become the standard treatment in patients with tumours \<7cm (T1). Even though this is a nephron sparing surgery, there is still potential for acute kidney injury, due to ischemia during the surgery. Remote Ischemia Preconditioning may prevent acute kidney injury and in turn chronic kidney disease. Remote Ischemia pre-conditioning involves applying a blood pressure cuff and inflating and deflating several times immediately prior to surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Renal Cell Carcinoma | Renal Cell Carcinoma | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CellAegis' autoRIC™ Device | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- PLACEBO_COMPARATOR
- label
- Without CellAegis' autoRIC™ Device
- description
- patients will have a blood pressure cuff attached to their arm that will not inflate/deflate as in the active group
- interventionNames
- Device: CellAegis' autoRIC™ Device
- type
- ACTIVE_COMPARATOR
- label
- With CellAegis' autoRIC™ Device
- description
- Patients will have the CellAegis' autoRIC™ Device attached and it will inflate to 200 mmHg in four 5 minute cycles with intervening 5 minutes of reperfusion with the cuff deflated between cycles (while under general anesthetic)
- interventionNames
- Device: CellAegis' autoRIC™ Device
Primary outcomes (1)
- measure
- Change in Kidney Function before and after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient must be a candidate for laparoscopic partial nephrectomy * ECOG Performance status of 0-1 Exclusion Criteria: * No diagnosis of any current cutaneous, vascular or neural disease in the right upper arm. * If the patient received isoflurane for any indication during the operation
References
Publications (0)
Data not yet available