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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
3,703 stopped studies mapped to Carcinoma and descendants · 91% state a reason
Over the 3,703 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00386555 | A Phase 2 Study in Patients With Advanced Non-Small Cell Lung Cancer Using New Agents… | Phase 2 | withdrawn | Oct 11, 2006 | Arog Pharmaceuticals, Inc. | Study was cancelled before patient enrollment | Enrollment / accrual |
| NCT00038038 | Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole | N/A | withdrawn | May 27, 2002 | M.D. Anderson Cancer Center | No participants enrolled, study terminated. | Enrollment / accrual |
| NCT00426829 | Proton Therapy and Bevacizumab for Primary Liver Tumors | Phase 1 | terminated | Jan 25, 2007 | M.D. Anderson Cancer Center | Low Accural | Other (stated, no rule matched) |
| NCT00048087 | Iressa/Docetaxel in Non-Small-Cell Lung Cancer | Phase 2 | withdrawn | Oct 25, 2002 | M.D. Anderson Cancer Center | Slow accrual. | Enrollment / accrual |
| NCT01070186 | Study of Sunitinib in Subjects With High Risk Renal Cell Carcinoma | Phase 2 | withdrawn | Feb 17, 2010 | Jonsson Comprehensive Cancer Center | No participants were enrolled. | Enrollment / accrual |
| NCT01373463 | Cisplatin and Pemetrexed With Radiation Followed by Lobectomy(CisPemXetSrg) | Phase 1 | terminated | Jun 15, 2011 | Medical University of South Carolina | Investigator left site | Investigator |
| NCT00605709 | Dose-Ranging Safety and Efficacy Study of Topical Creams Containing API 31510 for the… | Phase 2 | withdrawn | Jan 31, 2008 | BPGbio | not stated | Not stated |
| NCT00368329 | Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced… | Phase 1 | terminated | Aug 24, 2006 | Stanford University | low accrual | Enrollment / accrual |
| NCT01558778 | Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem… | N/A | withdrawn | Mar 20, 2012 | Roswell Park Cancer Institute | device not available | Other (stated, no rule matched) |
| NCT01314677 | Fludeoxyglucose F 18 PET/CT Scans in Predicting Therapy Response in Patients With Stage… | N/A | withdrawn | Mar 14, 2011 | City of Hope Medical Center | No subjects have been accrued to this trial. The PI will no longer be at COH and requests a study… | Enrollment / accrual |
| NCT00522938 | Clinical Trial of the Safety and Effectiveness of CHR-2797 With Erlotinib in Patients… | Phase 1 / Phase 2 | terminated | Aug 30, 2007 | Chroma Therapeutics | Very poor recruitment of patients to the study | Enrollment / accrual |
| NCT00442026 | Randomized Trial of Docetaxel and Gemcitabine Versus Gemcitabine in Elderly Patients With… | Phase 3 | terminated | Mar 1, 2007 | Hellenic Oncology Research Group | Due to poor accrual | Enrollment / accrual |
| NCT00562666 | Immunotherapy of Hepatocellular Carcinoma With Gamma Delta T Cells(ICAR) | Phase 1 | terminated | Nov 22, 2007 | Rennes University Hospital | not stated | Not stated |
| NCT00971191 | A Study In Patients Who Will Undergo Surgical Removal Of Non-Small Cell Lung Cancer To… | Phase 1 | terminated | Sep 3, 2009 | Pfizer | See termination reason in detailed description. | Other (stated, no rule matched) |
| NCT01197820 | Hepatic and Renal Thermography Using Magnetic Resonance Imaging(THeR-IRM) | N/A | terminated | Sep 9, 2010 | University Hospital, Bordeaux | not stated | Not stated |
| NCT01327521 | Transarterial Chemoembolization vs CyberKnife for Recurrent Hepatocellular Carcinoma | Phase 3 | withdrawn | Apr 1, 2011 | Albert Koong | Accrual below target levels | Enrollment / accrual |
| NCT00324558 | Adjuvant BEmiparin in Small Cell Lung Carcinoma (ABEL STUDY) | Phase 2 | terminated | May 11, 2006 | Clinica Universidad de Navarra, Universidad de Navarra | Sponsor stopped due to difficulties to recruit 130 patients required by protocol | Enrollment / accrual |
| NCT00618384 | TACE and Sorafenib for Advanced Hepatocellular Carcinoma (HCC)(SOCRATES) | Phase 2 | terminated | Feb 20, 2008 | Heinrich-Heine University, Duesseldorf | not stated | Not stated |
| NCT01491139 | Phase I Study of Olaparib With Cisplatin Based Chemoradiotherapy in Squamous Cell…(ORCA) | Phase 1 | withdrawn | Dec 13, 2011 | University College, London | Study stopped due to issues surrounding development and formulation of olaparib | Other (stated, no rule matched) |
| NCT01031056 | Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers | — | withdrawn | Dec 14, 2009 | Stanford University | Change in research focus | Other (stated, no rule matched) |
| NCT00042302 | A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Phase III Study of… | Phase 3 | terminated | Aug 1, 2002 | QLT Inc. | not stated | Not stated |
| NCT00042315 | A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Phase III Study of… | Phase 3 | terminated | Aug 1, 2002 | QLT Inc. | not stated | Not stated |
| NCT00311467 | Combined Treatment With Capecitabine and Immunotherapy Versus Immunotherapy Alone in… | Phase 3 | terminated | Apr 6, 2006 | Central European Cooperative Oncology Group | no patient recruitment | Enrollment / accrual |
| NCT00291850 | Phase II Trial of Dose-dense Paclitaxel and Cisplatin as Neo-adjuvant Chemotherapy for… | Phase 2 | terminated | Feb 15, 2006 | Central European Cooperative Oncology Group | no patient recruitment | Enrollment / accrual |
| NCT00100685 | Study of M200 (Volociximab) in Patients With Metastatic Renal Cell Carcinoma (RCC) | Phase 2 | terminated | Jan 5, 2005 | Abbott | not stated | Not stated |
| NCT01033981 | Cost Effectiveness Of Sunitinib In Central America And Caribbean | — | terminated | Dec 17, 2009 | Pfizer | See termination reason in detailed description. | Other (stated, no rule matched) |
| NCT01194206 | Stereotactic Body Radiation Therapy in Liver Cancer That Cannot be Removed by Surgery or… | Phase 2 | withdrawn | Sep 2, 2010 | Case Comprehensive Cancer Center | Study being rewritten | Other (stated, no rule matched) |
| NCT00515957 | Study of LMP1- and LMP2- Specific Cytotoxic T-Lymphocytes (CTL)(DELLA) | Phase 1 | withdrawn | Aug 14, 2007 | Baylor College of Medicine | not stated | Not stated |
| NCT01075607 | Lymph Fluid and Blood Collection for Identification of Novel Biomarkers | — | terminated | Feb 25, 2010 | Indiana University | Halted prematurely due to lack of funding. | Funding |
| NCT01337492 | Pilot Study Sorafenib as Bridge to Orthotopic Liver Transplantation (OLT) | Early Phase 1 | terminated | Apr 19, 2011 | Case Comprehensive Cancer Center | slow accrual | Enrollment / accrual |
| NCT01052766 | Breathing Synchronized PET/CT Scans for the Detection of Malignant Lung & Liver Lesions… | N/A | terminated | Jan 20, 2010 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT00485563 | A Phase II Study of EC17 (Folate-hapten Conjugate) in Patients With Progressive… | Phase 2 | terminated | Jun 13, 2007 | Endocyte | Changes in treatment paradigm resulted in a lower than expected rate of accrual. | Enrollment / accrual |
| NCT00151671 | Effect of a Perioperative Oral Nutritional Supplementation on Patients Undergoing Hepatic…(IMPACT) | Phase 2 / Phase 3 | terminated | Sep 9, 2005 | Rennes University Hospital | insufficient enrollment rate | Enrollment / accrual |
| NCT01318200 | Transarterial Chemoembolization (TACE) vs. CyberKnife for Recurrent Hepatocellular… | Phase 3 | withdrawn | Mar 18, 2011 | Accuray Incorporated | not stated | Not stated |
| NCT00696007 | Neoadjuvant Chemotherapy Plus Nephroureterectomy for Locally Advanced Upper Tract… | Phase 2 | withdrawn | Jun 12, 2008 | Lahey Clinic | Study was unable to recruit subjects meeting the study requirements. | Enrollment / accrual |
| NCT01063400 | Feasibility Study: Comparison of Performance Status With Objective Physical Activity… | — | terminated | Feb 5, 2010 | University of Wisconsin, Madison | lack of funding | Funding |
| NCT00472771 | INNO-206 in Patients With Small Cell Lung Cancer (SCLC) | Phase 2 | withdrawn | May 14, 2007 | CytRx | Terminated due to clinical trial material production delays | Other (stated, no rule matched) |
| NCT00363441 | A Study of Conventional 3D Radiation vs. Intensity-Modulated Radiation in Squamous Cell… | Phase 2 / Phase 3 | withdrawn | Aug 15, 2006 | Alberta Health services | not stated | Not stated |
| NCT00561912 | Low Dose Decitabine + Interferon Alfa-2b in Advanced Renal Cell Carcinoma | Phase 2 | terminated | Nov 21, 2007 | M.D. Anderson Cancer Center | Low accrual. | Enrollment / accrual |
| NCT00401401 | Zalutumumab in Combination With Chemotherapy and Radiotherapy in Head and Neck Cancer | Phase 1 / Phase 2 | terminated | Nov 20, 2006 | Genmab | MTD was established and patients completed 16 months safety f-up and response assessments. It is… | Safety / toxicity |
| NCT01441388 | A Study Of Crizotinib Plus VEGF Inhibitor Combinations In Patients With Advanced Solid… | Phase 1 | withdrawn | Sep 27, 2011 | Pfizer | Business/Operational issues | Sponsor / business decision |
| NCT01100489 | Breast-Conserving Surgery Followed by Radiation Therapy With MRI-Detected Stage I or… | Phase 2 | withdrawn | Apr 9, 2010 | Case Comprehensive Cancer Center | No accrual | Enrollment / accrual |
| NCT00410865 | Wild Type p53 Adenovirus for Oral Premalignancies | Phase 1 | terminated | Dec 13, 2006 | M.D. Anderson Cancer Center | Sponsor withdrawl prior to study completion. | Other (stated, no rule matched) |
| NCT00460551 | Zalutumumab in Combination With Chemo-Radiation in a Certain Type of Lung Cancer | Phase 2 | terminated | Apr 16, 2007 | Genmab | Due to considerations regarding the appropriate therapeutic regimen for these patients. | Other (stated, no rule matched) |
| NCT00593008 | Temsirolimus in Combination With Gemcitabine in Previously Untreated Metastatic… | Phase 1 | terminated | Jan 14, 2008 | Massachusetts General Hospital | not stated | Not stated |
| NCT00937300 | T-cell Based Immunotherapy for Head and Neck Cancer | Phase 1 | withdrawn | Jul 13, 2009 | Inge Marie Svane | The patients eligible for this trial do not exist anymore due to change in procedures. | Other (stated, no rule matched) |
| NCT01245582 | Oxaliplatin and Capecitabine on Top of Sorafenib Versus Sorafenib Alone in Advanced…(SECOX) | Phase 3 | withdrawn | Nov 22, 2010 | Sanofi | not stated | Not stated |
| NCT00225290 | Phase III Trial of Oral Thalidomide in Advanced Hepatocellular Carcinoma With Poor Liver… | Phase 3 | terminated | Sep 23, 2005 | TTY Biopharm | slowly recruitment rate | Enrollment / accrual |
| NCT01449357 | Zalutumumab in Non-Small Cell Lung Cancer (NSCLC) Patients Refractory to Tyrosine Kinase… | Phase 2 | withdrawn | Oct 10, 2011 | Genmab | Trial never initiated | Other (stated, no rule matched) |
| NCT00437749 | A Study of CBT-1 and Paclitaxel With Carboplatin in Patients With Advanced Inoperable… | Phase 3 | terminated | Feb 21, 2007 | CBA Research | slow accrual rate; interim accrual objective met | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Aug 9, 2012source: clinicaltrials