Clinical trial · Interventional
Hepatic and Renal Thermography Using Magnetic Resonance Imaging
NCT01197820CI-TRIAL-00007192THeR-IRMterminatedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Several technological challenges exist to apply Magnetic Resonance guided High Intensity Focused Ultrasound (MRgHIFU) for treatment of liver or kidney in particular challenges related to the motion of these organs. This study tests a new software to improve thermometry accuracy in mobile organs in patients with liver or kidney tumors. In the same time, the trajectory of the target in 3D is analyzed.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Kidney Carcinoma | Kidney Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Liver Tumors | Liver Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MRI | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Arm 1
- description
- 30 patients with liver tumour and 15 patients with kidney tumour will be enrolled.
- interventionNames
- Device: MRI
Primary outcomes (1)
- measure
- Temperature standard deviation
- timeFrame
- Duration of MRI specific sequence (15 min)
- description
- To test the ability of this method to improve thermometry accuracy, temperature standard deviations will be studied. Indeed, temperature standard deviations reflect thermometry inaccuracy in absence of temperature variations. Temperature standard deviation in each pixel will be measured over a temporal window. Two regions of interest (ROI) determined by the operator will be considered: the first one in the tumor, the second one for the whole organ.
Secondary outcomes (3)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Liver tumors treated or not : HCC, liver metastases of colorectal cancer, hepatocellular adenoma, focal and nodular hyperplasia, * Kidney tumors : carcinoma * more than 18 years old Exclusion Criteria: * Tumours of the liver dome * Deprived of their liberty by court * Pregnant woman * Contraindication to MRI examination * Contraindication to including gadolinium salts injection
References
Publications (0)
Data not yet available
No reference posted for this study.