Publication
Comprehensive mutation profiling of mucinous gastric carcinoma.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (10)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 10
- cancerGastric Carcinomacivic_curation1.00
- cancerMalignant Gastric Neoplasmcivic_curation1.00
- geneBCORcivic_curation1.00
- geneCDH1civic_curation1.00
- geneMLH1civic_curation1.00
- geneRHOAcivic_curation1.00
- variantBCOR Mutationcivic_curation1.00
- variantCDH1 MUTATIONcivic_curation1.00
- variantMLH1 EXPRESSIONcivic_curation1.00
- variantRHOA MUTATIONcivic_curation1.00
Curated evidence
Evidence citing this paper (4)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 27313181
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CDH1 MUTATION1 | ||||||||
| (prognostic) | Gastric CarcinomaALIAS | Prognostic | E | Supports Poor Outcome | 2 | accepted | EID1682285 intestinal-type tumors and 183 diffuse-type tumors were evaluated for mutational profiles. CDH1 mutations are associated with diffuse type mucinous gastric carcinoma, which indicate worse prognos… (full text at CIViC) PMID 27313181 · Rokutan et al., 2016 · Open in CIViC | civic |
| MLH1 EXPRESSION1 | ||||||||
| (prognostic) | Gastric CarcinomaALIAS | Prognostic | B | Supports Poor Outcome | 3 | accepted | EID168046 patients with poorly cohesive, signet-cell ring, gastric carcinoma were evaluated for genetic mutations and MLH1 expression (immunohistochemistry). Overall survival rate of MLH1 negative cases were… (full text at CIViC) PMID 27313181 · Rokutan et al., 2016 · Open in CIViC | civic |
| RHOA MUTATION1 | ||||||||
| (prognostic) | Gastric CarcinomaALIAS | Prognostic | E | Supports Poor Outcome | 2 | accepted | EID1683285 intestinal-type tumors and 183 diffuse-type tumors were evaluated for mutational profiles. RHOA mutations are associated with diffuse type mucinous gastric carcinoma, which indicate worse prognos… (full text at CIViC) PMID 27313181 · Rokutan et al., 2016 · Open in CIViC | civic |
| BCOR Mutation1 | ||||||||
| (prognostic) | Malignant Gastric Neoplasm | Prognostic | B | Supports Better Outcome | 3 | accepted | EID168146 patients with poorly cohesive, signet-cell ring, gastric carcinoma were evaluated for genetic mutations. Overall survival rate of BCOR positive cases were significantly better than BCOR negative c… (full text at CIViC) PMID 27313181 · Rokutan et al., 2016 · Open in CIViC | civic |