Publication
Integrated multimodal genetic testing of Ewing sarcoma--a single-institution experience.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (5)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 5
- cancerEwing Sarcomacivic_curation1.00
- geneERGcivic_curation1.00
- geneFLI1civic_curation1.00
- variantERG Fusioncivic_curation1.00
- variantFLI1 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 23706910
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| ERG Fusion1 | ||||||||
| (diagnostic) | Ewing Sarcoma | Diagnostic | B | Supports Positive | 5 | accepted | EID475The t(21;22) rearrangement resulting in the EWSR1::ERG fusion is associated with the diagnosis of Ewing sarcoma. EWSR1::ERG is the second most common gene fusion reported in this disease. PMID 23706910 · Warren et al., 2013 · Open in CIViC | civic |
| FLI1 Fusion1 | ||||||||
| (diagnostic) | Ewing Sarcoma | Diagnostic | B | Supports Positive | 5 | accepted | EID478t(11;22) rearrangements of EWSR1-FLI1 are diagnostic of ewing sarcoma, and are observed in 90% of cytogenetic samples. PMID 23706910 · Warren et al., 2013 · Open in CIViC | civic |