| NOTCH1 has variant …HAS_VARIANTderived88 of 88show fewer |
|---|
| → has variant | Mutationother 4 accepted CIViC evidence items | — | — | Chronic Lymphocytic Leukemia,Mantle Cell Lymphoma | 4 | Curated | civic | graph → |
| → has variant | Amplificationamplification 2 accepted CIViC evidence items | — | — | Malignant Colorectal Neoplasm | 2 | Curated | civic | graph → |
| → has variant | P2514FSindel 2 accepted CIViC evidence items | — | — | Chronic Lymphocytic Leukemia | 2 | Curated | civic | graph → |
| → has variant | D1642HSNV 1 accepted CIViC evidence items | — | — | Lung Non-Small Cell Carcinoma | 1 | Curated | civic | graph → |
| → has variant | Loss-of-function 1 accepted CIViC evidence items | — | — | Head and Neck Squamous Cell Carcinoma | 1 | Curated | civic | graph → |
| → has variant | R2327WSNV 1 accepted CIViC evidence items | — | — | Lung Non-Small Cell Carcinoma | 1 | Curated | civic | graph → |
| → has variant | S2275FSindel 1 accepted CIViC evidence items | — | — | Lung Non-Small Cell Carcinoma | 1 | Curated | civic | graph → |
| → has variant | V2444FSindel 1 accepted CIViC evidence items | — | — | Lung Non-Small Cell Carcinoma | 1 | Curated | civic | graph → |
| → has variant | C1685FSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | F1592CSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | F1592SSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | I1616NSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | L1574PSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | L1574QSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | L1585RSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | L1600PSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | L1600QSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | L1678PSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.1008TGA[1] (p.Asp338del)other no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.1013A>T (p.Asp338Val)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.1077C>T (p.Cys359=)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.1318_1320dup (p.Cys440_Leu441insCys)insertion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.1360_1362del (p.Asn454del)deletion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.1393G>A (p.Ala465Thr)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.1441+2T>ASNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.1441G>C (p.Gly481Arg)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.1461C>T (p.Cys487=)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.160_188del (p.Gly54fs)deletion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.1904-2A>GSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2205C>T (p.Asn735=)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2207+70G>ASNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2207+90A>GSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2207+9C>TSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2211C>A (p.Tyr737Ter)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2296G>A (p.Gly766Ser)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2353G>A (p.Gly785Ser)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2407del (p.Gln803fs)deletion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2587+129G>ASNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2652C>G (p.Cys884Trp)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2800C>G (p.Leu934Val)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2825G>A (p.Cys942Tyr)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.2884G>A (p.Asp962Asn)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.3171+42G>ASNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.3249C>T (p.Cys1083=)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.3294C>T (p.Ser1098=)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.329C>T (p.Pro110Leu)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.3510+148G>ASNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.3644-47G>TSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.3835C>T (p.Arg1279Cys)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.3902-1G>TSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.4014G>A (p.Ala1338=)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.4045_4052del (p.Ala1349fs)deletion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.4129C>T (p.Pro1377Ser)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.415C>T (p.Gln139Ter)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.4420T>G (p.Trp1474Gly)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.4721T>C (p.Leu1574Pro)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.4727T>A (p.Val1576Glu)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.4778T>C (p.Leu1593Pro)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.4793G>C (p.Arg1598Pro)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.4971C>T (p.Ser1657=)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.5118_5165dup (p.Val1721_Gln1722insHisAlaSerLeuGlySerLeuAsnIleProTyrLysIleGluAlaVal)insertion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.5124G>T (p.Ser1708=)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.5167+189C>ASNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.5200_5201insGCCGGGGCAGCTGCACTTCATGTACGTGGCGGCGGCCGCCTTTGC (p.Gln1733_Leu1734insArgArgGlySerCysThrSerCysThrTrpArgArgProProLeu)insertion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.5216_5217insCGCGGGTGAGACCGTGGAGCCGCCCCCGCCGGCGCAGCTGCACTTCATGTACGTinsertion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.52G>A (p.Ala18Thr)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.5700C>T (p.Ser1900=)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.5946del (p.Asn1983fs)deletion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.7005_7021del (p.Ser2336fs)deletion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.711C>T (p.Gly237=)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.7291_7313dup (p.Pro2438_Ser2439insGlyAlaSerTer)insertion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.7541_7542del (p.Pro2514fs)deletion no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | NM_017617.5(NOTCH1):c.973A>G (p.Asn325Asp)SNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | Q1614KSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | Q2315XSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | Q2391XSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | Q2409XSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | Q2459XSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | R1586PSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | R1598PSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | S2514ASNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | S2514ESNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | S2514PSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | T2512ASNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | V1577ASNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | V1577ESNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | V1676DSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |
| → has variant | Y1619NSNV no accepted CIViC evidence item (variant record only) | — | — | not mapped | 0 | Observed | civic | graph → |