MUC17

mucin 17, cell surface associated

Identifier: CI-GENE-00015909
Entity page: /gene/MUC17 ↗
Edges: 26

Neighbours: 24 cancers2 variants
Drawn: 26 of 26 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
MUC17 has variant …HAS_VARIANTderived2 of 2
→ has variant	NM_001040105.2(MUC17):c.8950G>A (p.Glu2984Lys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_001040105.2(MUC17):c.9447T>A (p.Ser3149=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed

MUC17 altered in cohorts of …ALTERED_INderived24 of 24show fewer
→ altered in cohorts of	Skin Basal Cell Carcinoma 66 / 126 cases (52 %) · ssm · bcc_unige_2016	—	—	Skin Basal Cell Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Skin Squamous Cell Carcinoma 27 / 83 cases (33 %) · ssm · cscc_ucsf_2021 · largest of 3 cohorts	—	—	Skin Squamous Cell Carcinoma	3	Observed	cbioportal	graph →
→ altered in cohorts of	Cutaneous Melanoma 139 / 469 cases (30 %) · ssm · skcm_tcga_gdc · largest of 7 cohorts	—	—	Cutaneous Melanoma	7	Observed	cbioportal	graph →
→ altered in cohorts of	Melanoma 41 / 144 cases (28 %) · ssm · mel_dfci_2019 · largest of 2 cohorts	—	—	Melanoma	2	Observed	cbioportal	graph →
→ altered in cohorts of	Pancreatic Adenocarcinoma 21 / 93 cases (23 %) · ssm · paad_iatlas_prince_2022	—	—	Pancreatic Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Lung Small Cell Carcinoma 27 / 120 cases (23 %) · ssm · sclc_ucologne_2015	—	—	Lung Small Cell Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Lung Adenocarcinoma 111 / 566 cases (20 %) · ssm · luad_tcga_pan_can_atlas_2018 · largest of 8 cohorts	—	—	Lung Adenocarcinoma	8	Observed	cbioportal	graph →
→ altered in cohorts of	Lung Non-Small Cell Carcinoma 219 / 1,144 cases (19 %) · ssm · nsclc_tcga_broad_2016	—	—	Lung Non-Small Cell Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Renal Cell Carcinoma 29 / 158 cases (18 %) · ssm · rcc_iatlas_immotion150_2018	—	—	Renal Cell Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Lung Squamous Cell Carcinoma 80 / 484 cases (17 %) · ssm · lusc_tcga_gdc · largest of 4 cohorts	—	—	Lung Squamous Cell Carcinoma	4	Observed	cbioportal	graph →
→ altered in cohorts of	Endometrial Carcinoma 84 / 517 cases (16 %) · ssm · ucec_tcga_pan_can_atlas_2018 · largest of 4 cohorts	—	—	Endometrial Carcinoma	4	Observed	cbioportal	graph →
→ altered in cohorts of	Gastroesophageal Junction Adenocarcinoma 60 / 518 cases (12 %) · ssm · stes_tcga_pub	—	—	Gastroesophageal Junction Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Endometrial Endometrioid Adenocarcinoma 27 / 247 cases (11 %) · ssm · uec_cptac_gdc	—	—	Endometrial Endometrioid Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Esophageal Adenocarcinoma 20 / 185 cases (11 %) · ssm · esca_tcga	—	—	Esophageal Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Diffuse Glioma 65 / 629 cases (10 %) · ssm · difg_glass · largest of 6 cohorts	—	—	Diffuse Glioma	6	Observed	cbioportal	graph →
→ altered in cohorts of	Cervical Squamous Cell Carcinoma 30 / 291 cases (10 %) · ssm · cesc_tcga_pan_can_atlas_2018 · largest of 2 cohorts	—	—	Cervical Squamous Cell Carcinoma	2	Observed	cbioportal	graph →
→ altered in cohorts of	Gastric Adenocarcinoma 47 / 478 cases (9.8 %) · ssm · stad_tcga · largest of 4 cohorts	—	—	Gastric Adenocarcinoma	4	Observed	cbioportal	graph →
→ altered in cohorts of	Colon Adenocarcinoma 41 / 429 cases (9.6 %) · ssm · coad_tcga_gdc	—	—	Colon Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Bladder Urothelial Carcinoma 41 / 474 cases (8.6 %) · ssm · blca_msk_tcga_2020 · largest of 5 cohorts	—	—	Bladder Urothelial Carcinoma	5	Observed	cbioportal	graph →
→ altered in cohorts of	Hepatocellular Carcinoma 39 / 494 cases (7.9 %) · ssm · hcc_clca_2024	—	—	Hepatocellular Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Head and Neck Squamous Cell Carcinoma 38 / 515 cases (7.4 %) · ssm · hnsc_tcga_pan_can_atlas_2018 · largest of 4 cohorts	—	—	Head and Neck Squamous Cell Carcinoma	4	Observed	cbioportal	graph →
→ altered in cohorts of	Prostate Adenocarcinoma 33 / 499 cases (6.6 %) · ssm · prad_tcga · largest of 2 cohorts	—	—	Prostate Adenocarcinoma	2	Observed	cbioportal	graph →
→ altered in cohorts of	Colorectal Adenocarcinoma 57 / 1,015 cases (5.6 %) · ssm · crc_sysucc_2022 · largest of 3 cohorts	—	—	Colorectal Adenocarcinoma	3	Observed	cbioportal	graph →
→ altered in cohorts of	High-Grade Serous Ovarian Cancer 21 / 405 cases (5.2 %) · ssm · hgsoc_tcga_gdc	—	—	High-Grade Serous Ovarian Cancer	1	Observed	cbioportal	graph →

MUC17 altered in cohorts of …ALTERED_INderived24 of 24show fewer

→ altered in cohorts of

Skin Basal Cell Carcinoma

66 / 126 cases (52 %) · ssm · bcc_unige_2016

—

Skin Basal Cell Carcinoma

Observed

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