| Lurbinectedin studied in …STUDIED_INderived59 of 59show fewer |
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| → studied in | NCT07155174Phase 2 · recruiting A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07365241Phase 3 · recruiting A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05153239Phase 3 · completed Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON) · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05578326Phase 2 · recruiting Study of Trilaciclib and Lurbinectidin · 59 trials list this drug (29 active) | — | — | Malignant Lung Neoplasm,Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07459634Phase 2 · recruiting A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05229588Phase 2 · completed Lurbinectedin in Patients With Advanced Gastrointestinal Malignancies With DNA Repair Mutations · 59 trials list this drug (29 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05091567Phase 3 · active not recruiting A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07640932Phase 2 · not yet recruiting Lurbinectedin Plus Paclitaxel Versus Paclitaxel in Patients With Previously Treated Small Cell Lung Cancer · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05918640Phase 1/Phase 2 · recruiting Lurbinectedin in FET-Fused Tumors · 59 trials list this drug (29 active) | — | — | Childhood Malignant Neoplasm,Ewing Sarcoma,Desmoplastic Small Round Cell Tumor+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07328425Phase 2 · recruiting Clinical Study in Adult and Young Adult Patients With Advanced Desmoplastic Small Round Cell Tumor (DSRCT) ISG-TULIPS · 59 trials list this drug (29 active) | — | — | Desmoplastic Small Round Cell Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05099666Phase 1/Phase 2 · active not recruiting Lurbinectedin + Doxorubicin In Leiomyosarcoma · 59 trials list this drug (29 active) | — | — | Sarcoma,Soft Tissue Sarcoma,Leiomyosarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05636111Phase 1 · recruiting Phase 1b of Lurbinectedin in Combination With Weekly Paclitaxel and Bevacizumab in Platinum-resistant Ovarian Cancer · 59 trials list this drug (29 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06228066Phase 2 · recruiting Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER) · 59 trials list this drug (29 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06801834Phase 3 · recruiting Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06203210Phase 3 · recruiting A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05652686Phase 1/Phase 2 · recruiting A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study) · 59 trials list this drug (29 active) | — | — | Neuroendocrine Carcinoma,Extrapulmonary Neuroendocrine Carcinoma,Large Cell Neuroendocrine Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06088290Phase 3 · active not recruiting Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo) · 59 trials list this drug (29 active) | — | — | Leiomyosarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07153055Phase 1/Phase 2 · recruiting Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06501976Phase 2 · active not recruiting An Exploratory Study of Lurbinectedin With Radiotherapy in SCLC With Single-lesion Progression After First Course Treatment · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06497530Phase 2 · recruiting Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05800587Phase 2 · recruiting Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer · 59 trials list this drug (29 active) | — | — | Malignant Lung Neoplasm,Lung Non-Small Cell Carcinoma,Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04607954Phase 2 · active not recruiting Durvalumab and Lurbinectedin for the Treatment of Relapsed or Refractory Small Cell Lung Cancer · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma,Platinum-Resistant Lung Small Cell Carcinoma,Platinum-Sensitive Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04802174Phase 1/Phase 2 · active not recruiting Lurbinectedin With Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and High-Grade Neuroendocrine Cancers · 59 trials list this drug (29 active) | — | — | Solid Neoplasm,Small Cell Neuroendocrine Carcinoma,Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06681220Phase 1/Phase 2 · recruiting Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04894591completed To Assess the Effectiveness and Safety of Zepzelca in Adult Patients With Extensive Stage Small Cell Lung Cancer (SCLC) · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05734066Phase 1/Phase 2 · recruiting Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma · 59 trials list this drug (29 active) | — | — | Ewing Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05740566Phase 3 · active not recruiting Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05244239Phase 1 · recruiting Palliative Radiotherapy With Lurbinectedin in Patients With Extensive Stage Small Cell Lung Cancer · 59 trials list this drug (29 active) | — | — | Malignant Lung Neoplasm,Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07121478Phase 2 · enrolling by invitation Patients With High-grade Pancreatic Neuroendocrine Tumors · 59 trials list this drug (29 active) | — | — | Pancreatic Neuroendocrine Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05072106Phase 1 · completed Study to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid Tumors · 59 trials list this drug (29 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07141771Phase 1/Phase 2 · not yet recruiting An Umbrella Study of Recurrent, Extensive Stage Small Cell Lung Cancer Based on Molecular Typing · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02611024Phase 1/Phase 2 · completed Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors · 59 trials list this drug (29 active) | — | — | Solid Neoplasm,Malignant Mesothelioma,Digestive System Neuroendocrine Tumor+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04358237Phase 1/Phase 2 · completed Lurbinectedin (PM01183) Combined With Pembrolizumab in Small Cell Lung Cancer. · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06385548Phase 1/Phase 2 · withdrawn Efficacy and Safety Study of Lurbinectedin and Dostarlimab in Cancer Patients: Protocol VHIO21001 - LiDer · 59 trials list this drug (29 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05126433Phase 2 · terminated Lurbinectedin Monotherapy in Participants With Advanced or Metastatic Solid Tumors · 59 trials list this drug (29 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06496048Phase 3 · recruiting Lurbinectedin or in Combination with Irinotecan Versus Topotecan in Patients with Relapsed SCLC · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06217536Phase 1/Phase 2 · withdrawn Neoadjuvant Lurbinectedin and Preoperative Radiation for Treating Soft Tissue Sarcomas · 59 trials list this drug (29 active) | — | — | Soft Tissue Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05876715Phase 1/Phase 2 · recruiting LINNOVATE: Lurbinectedin, Ipilimumab and Nivolumab for Soft Tissue Sarcoma · 59 trials list this drug (29 active) | — | — | Soft Tissue Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04638491Phase 1 · completed Safety Tolerability Pharmacokinetic and Preliminary Efficacy in Chinese Advanced Solid Tumors Patients · 59 trials list this drug (29 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04610658Phase 1 · terminated Immune Checkpoint Inhibition With Lurbinectedin Relapsed/Recurrent SCLC · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05101265Phase 1 · unknown Clinical Pharmacokinetic Study of Lurbinectedin in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Impairment · 59 trials list this drug (29 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04253145Phase 1/Phase 2 · unknown Study to Assess Safety,Tolerability,Efficacy of PM01183 and Atezolizumab in Patients w/ Advanced Small Cell Lung Cancer. · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02454972Phase 2 · completed Clinical Trial of Lurbinectedin (PM01183) in Selected Advanced Solid Tumors · 59 trials list this drug (29 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05285033completed RW Effectiveness of Lurbinectedin in Extensive Stage SCLC · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05042934Phase 1/Phase 2 · withdrawn Lurbinectedin With or Without Irinotecan in Treating Patients With Relapsed or High Risk Metastatic Ewing Sarcoma · 59 trials list this drug (29 active) | — | — | Ewing Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02566993Phase 3 · completed Clinical Trial of Lurbinectedin (PM01183)/Doxorubicin Versus CAV or Topotecan as Treatment in Patients With Small-Cell Lung Cancer · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03213301Phase 2 · completed Lurbinectedin Monotherapy in Patients With Progressive Malignant Pleural Mesothelioma. · 59 trials list this drug (29 active) | — | — | Pleural Malignant Mesothelioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02448537Phase 2 · completed A Phase II Multi-Strata Study of PM01183 as a Single Agent or in Combination With Conventional Chemotherapy in Metastatic and/or Unresectable Sarcomas · 59 trials list this drug (29 active) | — | — | Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01525589Phase 2 · completed A Phase II Clinical Trial of PM01183 in BRCA 1/2-Associated or Unselected Metastatic Breast Cancer · 59 trials list this drug (29 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04291937approved for marketing A Multicenter Expanded Access Treatment Protocol of Lurbinectedin in Previously Treated SCLC in the USA · 59 trials list this drug (29 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02421588Phase 3 · completed Clinical Trial of Lurbinectedin (PM01183) in Platinum Resistant Ovarian Cancer Patients · 59 trials list this drug (29 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01970540Phase 1 · completed Study Escalating Doses of PM01183 in Combination With Fixed Doxorubicin in Patients With Specific Advanced Unresectable Solid Tumors · 59 trials list this drug (29 active) | — | — | Neuroendocrine Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02451007Phase 2 · completed Evaluation of the Effect of Lurbinectedin (PM01183) on Cardiac Repolarization in Patients With Selected Solid Tumors · 59 trials list this drug (29 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01951157Phase 2 · completed A Clinical Study in Three-arm of Lurbinectedin (PM01183) Alone or in Combination With Gemcitabine and a Control Arm With Docetaxel as Second Line Treatment in Non-Small Cell Lung Cancer (NSCLC) Patients · 59 trials list this drug (29 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01980667Phase 1 · completed Study of Lurbinectedin (PM01183) in Combination With Cisplatin in Patients With Solid Tumors · 59 trials list this drug (29 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02210364Phase 1 · completed Study of Lurbinectedin (PM01183) in Combination With Capecitabine in Patients With Metastatic Breast Cancer (MBC), Pancreatic Cancer (PC) or Metastatic Colorectal Cancer (CRC). · 59 trials list this drug (29 active) | — | — | Malignant Breast Neoplasm,Malignant Pancreatic Neoplasm,Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01405391Phase 1 · completed Study of PM01183 in Non-Colorectal Cancer Patients as a Days 1 and 8 Intravenous Short Infusion Every 3 Weeks · 59 trials list this drug (29 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00877474Phase 1 · completed Phase I, Multicenter, Open-label, Dose-escalating, Clinical and Pharmacokinetic Study of PM01183 in Patients With Advanced Solid Tumors · 59 trials list this drug (29 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01970553Phase 1 · completed Escalating Doses of PM01183 in Combination With Gemcitabine in Patients With Specific Unresectable Solid Tumors · 59 trials list this drug (29 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |