| Guadecitabine studied in …STUDIED_INderived27 of 27show fewer |
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| → studied in | NCT03220477Phase 1 · active not recruiting Pembrolizumab (Immunotherapy Drug) in Combination With Guadecitabine and Mocetinostat (Epigenetic Drugs) for Patients With Advanced Lung Cancer. · 27 trials list this drug (6 active) | — | — | Malignant Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02935361Phase 1/Phase 2 · active not recruiting Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed · 27 trials list this drug (6 active) | — | — | Myelodysplastic Syndrome,Chronic Myelomonocytic Leukemia,Acute Myeloid Leukemia, Myelodysplasia-Related | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03257761Phase 1 · active not recruiting Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer · 27 trials list this drug (6 active) | — | — | Hepatocellular Carcinoma,Intrahepatic Cholangiocarcinoma,Malignant Gallbladder Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02998567Phase 1 · active not recruiting Combination Study of Guadecitabine/ASTX727 and Pembrolizumab · 27 trials list this drug (6 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02684162Phase 2 · completed Guadecitabine and Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapsing After Allogeneic Stem Cell Transplant · 27 trials list this drug (6 active) | — | — | Myelodysplastic Syndrome,Acute Myeloid Leukemia,Chronic Myelomonocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03206047Phase 1/Phase 2 · completed Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer · 27 trials list this drug (6 active) | — | — | Primary Peritoneal Carcinoma,Ovarian Carcinoma,Platinum-Resistant Primary Peritoneal Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01261312Phase 1/Phase 2 · completed SGI-110 in Participants With Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML) · 27 trials list this drug (6 active) | — | — | Myelodysplastic Syndrome,Acute Myeloid Leukemia,Chronic Myelomonocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02920008Phase 3 · completed Phase 3 Randomized, Open-Label Study of Guadecitabine vs Treatment Choice in Previously Treated Acute Myeloid Leukemia · 27 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01696032Phase 2 · completed SGI-110 in Combination With Carboplatin in Ovarian Cancer · 27 trials list this drug (6 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01752933Phase 2 · completed SGI-110 in the Treatment of Advanced Hepatocellular Carcinoma (HCC) · 27 trials list this drug (6 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02096055Phase 2 · completed Guadecitabine With or Without Idarubicin or Cladribine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia · 27 trials list this drug (6 active) | — | — | Adult Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02907359Phase 3 · completed Guadecitabine (SGI-110) vs Treatment Choice in Adults With MDS or CMML Previously Treated With HMAs · 27 trials list this drug (6 active) | — | — | Leukemia,Myelodysplastic Syndrome | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03603964Phase 2 · terminated Guadecitabine Extension Study · 27 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02901899Phase 2 · completed Guadecitabine and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer · 27 trials list this drug (6 active) | — | — | Primary Peritoneal Carcinoma,Ovarian Carcinoma,Fallopian Tube Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03913455Phase 2 · completed Guadecitabine in Combination With Carboplatin in Extensive Stage Small Cell Lung Cancer · 27 trials list this drug (6 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03075826Phase 2 · completed A Phase II Study of SGI-110 in Philadelphia-Negative Myeloproliferative Neoplasms · 27 trials list this drug (6 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03308396Phase 1/Phase 2 · active not recruiting Study of Durvalumab and Guadecitabine in Advanced Kidney Cancer · 27 trials list this drug (6 active) | — | — | Malignant Kidney Neoplasm,Clear Cell Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03179943Phase 2 · active not recruiting Atezolizumab + Guadecitabine in Patients With Checkpoint Inhibitor Refractory or Resistant Urothelial Carcinoma · 27 trials list this drug (6 active) | — | — | Urothelial Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03576963Phase 1/Phase 2 · withdrawn Guadecitabine and Nivolumab in Treating Refractory Metastatic Colorectal Cancer · 27 trials list this drug (6 active) | — | — | Colorectal Adenocarcinoma,Colorectal Carcinoma,Malignant Colorectal Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01966289Phase 1 · completed SGI-110 in Combination With an Allogeneic Colon Cancer Cell Vaccine (GVAX) and Cyclophosphamide (CY) in Metastatic Colorectal Cancer (mCRC) · 27 trials list this drug (6 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02293993Phase 1 · completed Phase 1 Study of SGI-110 in Patients With Acute Myeloid Leukemia · 27 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01896856Phase 1/Phase 2 · completed Phase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer · 27 trials list this drug (6 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02429466Phase 1 · completed Study of the Hypomethylating Drug Guadecitabine (SGI-110) Plus Cisplatin in Relapsed Refractory Germ Cell Tumors · 27 trials list this drug (6 active) | — | — | Germ Cell Tumor,Malignant Testicular Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02892318Phase 1 · completed A Study Evaluating the Safety and Pharmacology of Atezolizumab Administered in Combination With Immunomodulatory Agents in Participants With Acute Myeloid Leukemia (AML) · 27 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03085849Phase 1 · completed SGI-110 Plus Durvalumab/Tremelimumab in SCLC · 27 trials list this drug (6 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03454984Phase 2 · unknown SGI-110 and Donor Lymphocyte Infusions (DLI) After Allogeneic Stem Cell Transplantation · 27 trials list this drug (6 active) | — | — | Myelodysplastic Syndrome,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02608437Phase 1 · unknown A Study Investigating SGI-110 in Combination With Ipilimumab in Unresectable or Metastatic Melanoma Patients · 27 trials list this drug (6 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |