| Aflibercept studied in …STUDIED_INderived75 of 75show fewer |
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| → studied in | NCT02298959Phase 1 · active not recruiting Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer · 75 trials list this drug (2 active) | — | — | Malignant Solid Neoplasm,Melanoma,Sarcoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06121180Phase 2 · recruiting Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma · 75 trials list this drug (2 active) | — | — | Uveal Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02159989Phase 1 · completed Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery · 75 trials list this drug (2 active) | — | — | Solid Neoplasm,Malignant Solid Neoplasm,Ovarian Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03712904Phase 2 · terminated Stereotactic Body Radiation Therapy and Aflibercept in Treating Patients With Uveal Melanoma · 75 trials list this drug (2 active) | — | — | Uveal Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00532155Phase 3 · completed A Study of Aflibercept Versus Placebo in Patients With Second-Line Docetaxel for Locally Advanced or Metastatic Non-Small-Cell Lung Cancer · 75 trials list this drug (2 active) | — | — | Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03186326Phase 2 · completed Standard Chemotherapy vs Immunotherapie in 2nd Line Treatment of MSI Colorectal Mestastatic Cancer · 75 trials list this drug (2 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03172299Phase 3 · completed Prevention of Neovascular Glaucoma by Intravitreal Injections of Anti-VEGF in Patients Treated with Proton Therapy for a Large Choroidal Melanoma · 75 trials list this drug (2 active) | — | — | Ocular Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01652196Phase 2 · completed Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Colon Mucinous Adenocarcinoma,Malignant Colon Neoplasm,Malignant Rectal Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05178745completed Resection Observatory · 75 trials list this drug (2 active) | — | — | Colorectal Neoplasm,Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02384759Phase 2 · completed Aflibercept +/- LV5FU2 in First Line of Non-resectalbe Metastatic Colorectal Cancers · 75 trials list this drug (2 active) | — | — | Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00407654Phase 2 · completed VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Malignant Colon Neoplasm,Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01782443Phase 2 · completed Ziv-Aflibercept for Advanced Progressive Carcinoid Tumors · 75 trials list this drug (2 active) | — | — | Neuroendocrine Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03279289Phase 2 · completed Study to Assess the Efficacy and Safety of Treatment With FOLFIRI-aflibercept Compared to Initial Treatment With FOLFIRI-aflibercept (for 6 Cycles) Followed by Maintenance With 5FU-aflibercept, in an Elderly Population With mCRC After Failure of an Oxaliplatin-based Regimen · 75 trials list this drug (2 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03043729Phase 2 · completed mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer · 75 trials list this drug (2 active) | — | — | Malignant Rectal Neoplasm,Malignant Rectosigmoid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03710564Phase 3 · terminated Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg Dosed Every 4 Weeks in Patients With Retinal Fluid Despite Frequent Anti-VEGF Injections · 75 trials list this drug (2 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02181556Phase 2 · completed Efficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients With Metastatic Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02340949Phase 2 · completed Induction FOLFOX With or Without Aflibercept Followed by Chemoradiation in High Risk Locally Advanced Rectal Cancer · 75 trials list this drug (2 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00437034Phase 2 · terminated Aflibercept for Relapsed Multiple Myeloma · 75 trials list this drug (2 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00794417Phase 1/Phase 2 · terminated A Study of Aflibercept Administered in Combination With Pemetrexed and Cisplatin in Participants With Advanced Carcinoma · 75 trials list this drug (2 active) | — | — | Carcinoma,Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02101918Phase 2 · completed Ziv-Aflibercept in Treating and Computed Tomography Perfusion Imaging in Predicting Response in Patients With Pancreatic Neuroendocrine Tumors That Are Metastatic or Cannot Be Removed by Surgery · 75 trials list this drug (2 active) | — | — | Multiple Endocrine Neoplasia Type 1,Pancreatic Neuroendocrine Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01669720Phase 2 · terminated Adjuvant Aflibercept for Metastatic Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01747551Phase 2 · completed FOLFOX +/- Ziv-Aflibercept for Esophageal and Gastric Cancer · 75 trials list this drug (2 active) | — | — | Malignant Esophageal Neoplasm,Malignant Gastric Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02331927Phase 2 · unknown PERMAD: Personalized Marker-driven Early Switch to Aflibercept in Patients With Metastatic Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00462826Phase 2 · completed VEGF Trap in Treating Patients With Recurrent or Persistent Endometrial Cancer · 75 trials list this drug (2 active) | — | — | Endometrial Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01258855Phase 2 · completed Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery · 75 trials list this drug (2 active) | — | — | Melanoma,Cutaneous Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00436501Phase 1/Phase 2 · completed VEGF Trap and Docetaxel in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer · 75 trials list this drug (2 active) | — | — | Malignant Fallopian Tube Neoplasm,Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02624726Phase 2 · unknown Trial in Metastatic Colorectal Cancer With FOLFIRI Plus Aflibercept as First Line Treatment · 75 trials list this drug (2 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00450255Phase 2 · completed VEGF Trap in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery · 75 trials list this drug (2 active) | — | — | Melanoma,Uveal Melanoma,Iris Melanoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01571284Phase 3 · completed Safety and Quality of Life Study of Aflibercept in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin-Based Regimen · 75 trials list this drug (2 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02192541Phase 1 · terminated Ganetespib and Ziv-Aflibercept in Refractory Gastrointestinal Carcinomas, Non-Squamous Non-Small Cell Lung Carcinomas, Urothelial Carcinomas, and Sarcomas · 75 trials list this drug (2 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01843725Phase 1 · completed Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers · 75 trials list this drug (2 active) | — | — | Malignant Breast Neoplasm,Malignant Gastric Neoplasm,Malignant Pancreatic Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02129257Phase 2 · completed Clinical Trial of Combination Chemotherapy With Aflibercept in Patients With Advanced Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03264274Phase 2 · withdrawn Trial of Aflibercept Monotherapy With DCE-US in Chemorefractory Metastatic Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00828139Phase 2 · completed S0802 - Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer · 75 trials list this drug (2 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00357760Phase 2 · completed Ziv-Aflibercept in Treating Patients With Metastatic or Unresectable Kidney Cancer · 75 trials list this drug (2 active) | — | — | Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01646554Phase 2/Phase 3 · withdrawn Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases · 75 trials list this drug (2 active) | — | — | Colorectal Carcinoma with KRAS Mutation | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00729157Phase 2 · completed Aflibercept in Treating Patients With Recurrent and/or Metastatic Thyroid Cancer That Did Not Respond to Radioactive Iodine Therapy · 75 trials list this drug (2 active) | — | — | Thyroid Gland Follicular Carcinoma,Thyroid Gland Carcinoma,Thyroid Gland Papillary Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01882868Phase 2 · completed A Study of Aflibercept in Combination With FOLFIRI in Patients With Second-Line Metastatic Colorectal Cancer in Japan · 75 trials list this drug (2 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01802684Phase 2 · completed OPTIMOX-aflibercept as First-line Therapy in Patients With Unresectable Metastatic Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01749956Phase 2 · completed 5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer · 75 trials list this drug (2 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01670721Phase 3 · completed Colorectal Cancer Metastatic · 75 trials list this drug (2 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01661270Phase 3 · completed A Study of Aflibercept Versus Placebo With FOLFIRI in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin Chemotherapy · 75 trials list this drug (2 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00519285Phase 3 · completed Aflibercept in Combination With Docetaxel in Metastatic Androgen Independent Prostate Cancer · 75 trials list this drug (2 active) | — | — | Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00327171Phase 2 · completed Study of AVE0005 (VEGF Trap) in Patients With Chemoresistant Advanced Ovarian Cancer · 75 trials list this drug (2 active) | — | — | Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00574275Phase 3 · terminated Aflibercept Compared to Placebo in Term of Efficacy in Patients Treated With Gemcitabine for Metastatic Pancreatic Cancer · 75 trials list this drug (2 active) | — | — | Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00851084Phase 2 · completed Study of Aflibercept And Modified FOLFOX6 As First-Line Treatment In Patients With Metastatic Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00036946Phase 1 · completed VEGF Trap in Treating Patients With Relapsed or Refractory Solid Tumors or Non-Hodgkin's Lymphoma · 75 trials list this drug (2 active) | — | — | Adult Solid Neoplasm,Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00045266Phase 1 · completed VEGF Trap in Treating Patients With Solid Tumors or Non-Hodgkin's Lymphoma · 75 trials list this drug (2 active) | — | — | Adult Solid Neoplasm,Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00082823Phase 1 · completed Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma · 75 trials list this drug (2 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00083213Phase 1 · completed Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma · 75 trials list this drug (2 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00644124Phase 1 · completed Aflibercept and Standard Chemotherapy (R-CHOP) in First Line of Non Hodgkin B-cell Lymphoma · 75 trials list this drug (2 active) | — | — | Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00876044Phase 1 · completed A Study to Evaluate the Effects of Aflibercept on QTc Interval in Cancer Patients · 75 trials list this drug (2 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01955629Phase 1/Phase 2 · terminated Study of Aflibercept as Maintenance Therapy Following Induction With Aflibercept in Combination With XELOX, as First-Line Treatment for Metastatic Colorectal Cancer Patient · 75 trials list this drug (2 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00390234Phase 2 · completed Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma · 75 trials list this drug (2 active) | — | — | Malignant Fallopian Tube Neoplasm,Ovarian Carcinoma,Ovarian Sarcoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00369590Phase 2 · completed VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide · 75 trials list this drug (2 active) | — | — | Adult Anaplastic Astrocytoma,Adult Anaplastic Oligodendroglioma,Adult Giant Cell Glioblastoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02235324Phase 2 · withdrawn Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Colon Mucinous Adenocarcinoma,Malignant Colon Neoplasm,Malignant Rectal Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01688960Phase 1 · completed Nesvacumab (REGN910/ SAR307746) and Aflibercept ("Ziv-aflibercept" in the U.S.) in Patients With Advanced Solid Malignancies · 75 trials list this drug (2 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00509249Phase 2 · terminated Aflibercept in Treating Patients With Myelodysplastic Syndromes · 75 trials list this drug (2 active) | — | — | Myelodysplastic Syndrome,Atypical Chronic Myeloid Leukemia,Chronic Myelomonocytic Leukemia+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01930552Phase 1 · completed A Phase I Study of Aflibercept Plus FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin) in Chinese Patients With Advanced Solid Malignancies · 75 trials list this drug (2 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01889680Phase 2 · withdrawn Safety and Effectiveness Study of Chemotherapy and Ziv-aflibercept to Treat Metastatic Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02085005Phase 2 · withdrawn Capecitabine Plus Aflibercept as Maintenance Therapy Following Capecitabine Plus Oxaliplatin Plus Aflibercept in Patients With Metastatic Colorectal Cancer · 75 trials list this drug (2 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00407485Phase 2 · completed VEGF Trap in Treating Patients With Recurrent, Locally Advanced, or Metastatic Cancer of the Urothelium · 75 trials list this drug (2 active) | — | — | Bladder Squamous Cell Carcinoma,Malignant Bladder Neoplasm,Malignant Urethral Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01941173NA · withdrawn Short-Infusion Ziv-aflibercept in Treating Patients With Metastatic Colorectal Cancer Receiving Combination Chemotherapy · 75 trials list this drug (2 active) | — | — | Malignant Colon Neoplasm,Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00650923Phase 1 · completed Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma · 75 trials list this drug (2 active) | — | — | Adult Mixed Glioma,Adult Anaplastic Astrocytoma,Adult Anaplastic Oligodendroglioma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00369655Phase 2 · completed VEGF Trap in Treating Patients With Metastatic Breast Cancer · 75 trials list this drug (2 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00622414Phase 1 · completed Aflibercept in Treating Young Patients With Relapsed or Refractory Solid Tumors · 75 trials list this drug (2 active) | — | — | Childhood Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00545246Phase 1 · completed A Phase I Study of Intravenous Aflibercept in Combination With Docetaxel in Japanese Cancer Patients · 75 trials list this drug (2 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00601991Phase 2 · withdrawn A Multi-Center Phase 2 Study of VEGF Trap as a Single Agent in Acute Myeloid Leukemia · 75 trials list this drug (2 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00396591Phase 2 · completed AVE0005 (VEGF Trap) in Patients With Recurrent Symptomatic Malignant Ascites · 75 trials list this drug (2 active) | — | — | Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00327444Phase 2/Phase 3 · completed Study of the Effect of Intravenous AVE0005 (VEGF Trap) in Advanced Ovarian Cancer Patients With Recurrent Symptomatic Malignant Ascites · 75 trials list this drug (2 active) | — | — | Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00284141Phase 2 · completed Study of AVE0005 (VEGF Trap) in Locally Advanced or Metastatic Platinum- and Erlotinib- Resistant Non-small-cell-lung Adenocarcinoma · 75 trials list this drug (2 active) | — | — | Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00921661Phase 1 · completed Study of Intravenous Aflibercept in Combination With FOLFIRI in Japanese Patients With Metastatic Colorectal Cancer · 75 trials list this drug (2 active) | — | — | Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00561470Phase 3 · completed Aflibercept Versus Placebo in Combination With Irinotecan and 5-FU in the Treatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based Regimen · 75 trials list this drug (2 active) | — | — | Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01148615Phase 1 · completed A Study of Intravenous Aflibercept With Docetaxel in Chinese Patients With Solid Tumors · 75 trials list this drug (2 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00479076Phase 1 · completed A Phase I Study of Intravenous Aflibercept in Combination With S-1 in Japanese Cancer Patients · 75 trials list this drug (2 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |