PXDNL

peroxidasin like

Explore in graph →CI-GENE-00022620HGNC:26359 ENSG00000147485 NCBI 137902 CIViC Cancer geneApproved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
PXDNL P1460T1
Pembrolizumab	Lung Adenocarcinoma	Predictive	C	Supports Sensitivity Response	—	submitted	EID4773 In a retrospective study of 34 non-small cell lung cancer patients, a lung adenocarcinoma patient with PXDNL deleterious P1460T mutation, treated with pembrolizumab monotherapy, was associated with a … (full text at CIViC) PMID 25765070 · Rizvi et al., 2015 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (71)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved71 cohort rows (showing 21, sorted by frequency) · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Esophageal Adenocarcinoma (TCGA, PanCancer Atlas) esca_tcga_pan_can_atlas_2018	Esophageal Adenocarcinoma

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.