Gene
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Explore in graph →CI-GENE-00017552HGNC:15719 ENSG00000154358 NCBI 84033 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (200)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| The Metastatic Breast Cancer Project (Provisional, December 2021) brca_mbcproject_2022 | Invasive Breast Carcinoma | Ssm | 27 | 379 | 7.1% | 18 | cbioportal |
| Cancer Cell Line Encyclopedia (Genentech, Nat biotech 2014) ccle_genentech_2014 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.