Gene

CEACAM1

CEA cell adhesion molecule 1

Explore in graph →CI-GENE-00040864HGNC:1814 ENSG00000079385 NCBI 634 CIViC Approved

Curated evidence

Clinical evidence (3)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–3 of 3 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
CEACAM1 CEACAM1-L2
(prognostic)	Malignant Colorectal NeoplasmCURATED_BROADER	Prognostic	B	Supports Poor Outcome	4	submitted	EID9605 In a clinical study including 164 patients, CEACAM1-L dominant expression is significantly associated with decreased OS by a multivariate analysis (p = 0.02). PMID 21413011 · Ieda et al., 2011 · Open in CIViC	civic
〃	Hepatocellular Carcinoma	Prognostic	B	Supports Poor Outcome	4	submitted	EID9606 In a clinical study including 128 patients, CEACAM1-L dominant expression is significantly associated with decreased recurrence-free survival rate by a multivariate analysis (p = 0.04). Moreover CEACA… (full text at CIViC) PMID 24390710 · Kiriyama et al., 2014 · Open in CIViC

Cohorts

Alteration frequency by cohort (3)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved3 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Thymic Epithelial Tumors (NCI, Nat Genet 2014) tet_nci_2014	Thymus Epithelial Neoplasm	Ssm	1	32

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.