Variant
CEACAM1 CEACAM1-L
CI-VAR-00000379Explore in graph →CIViC 3474
Curated evidence
Evidence by cancer (2 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 24390710
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| Hepatocellular Carcinoma1 | ||||||||
| CEACAM1 CEACAM1-L | (prognostic) | Prognostic | B | Supports Poor Outcome | 4 | submitted | EID9606In a clinical study including 128 patients, CEACAM1-L dominant expression is significantly associated with decreased recurrence-free survival rate by a multivariate analysis (p = 0.04). Moreover CEACA… (full text at CIViC) PMID 24390710 · Kiriyama et al., 2014 · Open in CIViC | civic |
| Malignant Colorectal Neoplasm1 | ||||||||
| CEACAM1 CEACAM1-L | (prognostic) | Prognostic | B | Supports Poor Outcome | 4 | submitted | EID9605In a clinical study including 164 patients, CEACAM1-L dominant expression is significantly associated with decreased OS by a multivariate analysis (p = 0.02). PMID 21413011 · Ieda et al., 2011 · | |
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available