ARID1B Mutation

CI-VAR-00002831Explore in graph →CIViC 5315

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Unmapped disease1unmapped disease
ARID1A Mutation OR ARID1B Mutation	(functional)	Functional	B	Supports Loss Of Function	3	submitted	EID12642 Concurrent inactivating mutations in ARID1A and ARID1B were identified in 12 of 24 BRG1/INI1-intact dedifferentiated endometrial or ovarian carcinomas, with all co-mutated tumours showing complete los… (full text at CIViC) PMID 27562491 · Coatham et al., 2016 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.