Histology
WNT-Activated Deep Penetrating/Plexiform Melanocytoma (Nevus)
CI-CAN-00001661Explore in graph →
Non-malignant
- NCIt
- C204514
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Histology
CI-CAN-00001661Explore in graph →
Data completeness1 / 7 dimensions
Computed from entity_counters.completeness · refreshed after each connector run
Definition
A benign melanocytic neoplasm composed of spindle and/or epithelioid melanocytes and melanophages. It is caused by the combined activation of the WNT signaling and MAP-kinase pathways. It occurs in the head and neck region, trunk, extremities, and conjunctiva. It presents with well-circumscribed, darkly pigmented papules. The neoplastic melanocytes form wedge-shaped, fascicular, or plexiform patterns. Lesions with a wedge-shaped pattern extend into the deep reticular dermis. In plexiform spindle cell lesions, the neoplastic melanocytes proliferate in the upper dermis. A junctional component is present in the majority of cases. It rarely progresses to melanoma.
Data updated 23 days agoSource updated 26.08e
Taxonomy
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Parents
Anatomy
Data not yet available
Data updated 16 hours agoSource updated unknowncounters aggregate over descendants
Names
Only the preferred name is recorded so far.
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Key figures
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No registry-level ancestor: burden figures are published for the mutually exclusive top-level site groups only, and this entity does not descend from one. Global figures (IARC / GLOBOCAN) stay under license review and SEER awaits credentials.
Data updated 16 hours agoSource updated unknownregistry figures: none · counters aggregate over descendants