Subtype
WHO Grade 4 Glioma
CI-CAN-00007117Explore in graph →
535 active trials3 approved drugs58 evidence items
- NCIt
- C200758
Loading cancer entity…
Loading cancer entity…
Subtype
CI-CAN-00007117Explore in graph →
Clinical trials
1,854 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (301)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02899663 | MRI Detection of Microbleeds in Glioma Patients(SWIGLI) | completed | — | 58 | Fondation Ophtalmologique Adolphe de RothschildNETWORK | 0 | Sep 14, 2016 | clinicaltrials |
| NCT02898012 | Temozolomide Plus Bevacizumab in Supratentorial Glioblastoma in 70 Years and Older Patients With an Impaired Functional Status(ATAG) | completed | Phase 2 | 70 | Assistance Publique - Hôpitaux de ParisOTHER |
| 1 |
| Sep 13, 2016 |
| clinicaltrials |
| NCT00544817 | Radiation Therapy and Temozolomide Followed by Temozolomide Plus Sorafenib for Glioblastoma Multiforme | completed | Phase 2 | 47 | SCRI Development Innovations, LLCOTHER | 1 | Sep 1, 2016 | clinicaltrials |
| NCT00302159 | Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors | completed | Phase 2 | 43 | National Cancer Institute (NCI)NIH | 1 | Aug 18, 2016 | clinicaltrials |
| NCT01331291 | Bosutinib in Adult Patients With Recurrent Glioblastoma | completed | Phase 2 | 36 | Massachusetts General HospitalOTHER | 1 | Jul 25, 2016 | clinicaltrials |
| NCT00864864 | Sunitinib Tumor Levels in Patients Not on Enzyme-Inducing Anti-Epileptic Drugs Undergoing Debulking Surgery for Recurrent Glioblastoma | completed | Early Phase 1 | 8 | Massachusetts General HospitalOTHER | 1 | Jul 7, 2016 | clinicaltrials |
| NCT01588769 | A Phase I Study to Investigate Tolerability and Efficacy of ALECSAT Administered to Glioblastoma Multiforme Patients(ALECSAT-GBM) | completed | Phase 1 | 23 | CytoVac A/SINDUSTRY | 1 | Jun 6, 2016 | clinicaltrials |
| NCT01833273 | Dose Evaluation Safety STudy IN Individuals With Astrocytoma Taking PolyMVA(DESSTINI_A) | completed | Phase 1 | 13 | Stony Brook UniversityOTHER | 1 | Jun 3, 2016 | clinicaltrials |
| NCT01144247 | Cellular Immunotherapy Study for Brain Cancer(alloCTL) | completed | Phase 1 | 10 | Jonsson Comprehensive Cancer CenterOTHER | 1 | May 27, 2016 | clinicaltrials |
| NCT00267592 | Safety and Efficacy of Talampanel in Glioblastoma Multiforme | completed | Phase 2 | 72 | Teva Branded Pharmaceutical Products R&D, Inc.INDUSTRY | 0 | May 19, 2016 | clinicaltrials |
| NCT01213407 | Dendritic Cell Cancer Vaccine for High-grade Glioma(GBM-Vax) | completed | Phase 2 | 87 | Activartis BiotechINDUSTRY | 1 | May 19, 2016 | clinicaltrials |
| NCT00445588 | Erlotinib and Sorafenib in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme | completed | Phase 2 | 56 | National Cancer Institute (NCI)NIH | 1 | Apr 27, 2016 | clinicaltrials |
| NCT01435395 | Trial of Temozolomide, Bevacizumab Plus Bortezomib for Recurrent Glioblastoma Multiforme | completed | Phase 1 | 12 | Emory UniversityOTHER | 1 | Apr 27, 2016 | clinicaltrials |
| NCT01475006 | AMG 595 First-in-Human in Recurrent Gliomas | completed | Phase 1 | 32 | AmgenINDUSTRY | 2 | Apr 15, 2016 | clinicaltrials |
| NCT00995007 | A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas | completed | Phase 2 | 112 | National Cancer Institute (NCI)NIH | 1 | Mar 29, 2016 | clinicaltrials |
| NCT01474239 | A Study of Avastin (Bevacizumab) And Fotemustine in Patients With Recurrent Glioblastoma | completed | Phase 2 | 91 | Hoffmann-La RocheINDUSTRY | 1 | Mar 15, 2016 | clinicaltrials |
| NCT00499473 | Sunitinib in Treating Patients With Recurrent Malignant Gliomas | completed | Phase 2 | 31 | National Cancer Institute (NCI)NIH | 1 | Feb 29, 2016 | clinicaltrials |
| NCT00085254 | Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | completed | Phase 1 / Phase 2 | 112 | National Cancer Institute (NCI)NIH | 1 | Feb 25, 2016 | clinicaltrials |
| NCT01364064 | Conventional Adjuvant Temozolomide With Dose Intensive Temozolomide in Patients With Newly Diagnosed Glioblastoma | completed | Phase 3 | 1,153 | King Faisal Specialist Hospital & Research CenterOTHER | 0 | Feb 25, 2016 | clinicaltrials |
| NCT00250211 | Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide | completed | Phase 1 / Phase 2 | 26 | AHS Cancer Control AlbertaOTHER | 1 | Feb 24, 2016 | clinicaltrials |
| NCT01663012 | Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma | completed | Phase 2 | 20 | Lawrence RechtOTHER | 1 | Feb 24, 2016 | clinicaltrials |
| NCT00301418 | Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma | completed | Phase 1 / Phase 2 | 11 | Northwell HealthOTHER | 1 | Feb 10, 2016 | clinicaltrials |
| NCT01345370 | Comparison of Different Methods to Test MGMT Status in Glioblastoma Patients(ECOM) | completed | — | 300 | Center Eugene MarquisOTHER | 1 | Jan 29, 2016 | clinicaltrials |
| NCT01113398 | AMG 102 and Avastin for Recurrent Malignant Glioma | completed | Phase 2 | 36 | Katy PetersOTHER | 1 | Dec 10, 2015 | clinicaltrials |
| NCT00967330 | A Study of Avastin (Bevacizumab) and Irinotecan Versus Temozolomide Radiochemistry in Patients With Glioblastoma | completed | Phase 2 | 182 | Hoffmann-La RocheINDUSTRY | 1 | Nov 20, 2015 | clinicaltrials |
| NCT00116376 | Study of AEE788 in Patients With Recurrent/Relapse Glioblastoma Multiforme (GBM) | completed | Phase 1 / Phase 2 | 64 | Novartis PharmaceuticalsINDUSTRY | 1 | Nov 10, 2015 | clinicaltrials |
| NCT02092038 | Preoperative Chemoradiation for Glioblastoma | completed | Phase 1 | 1 | Tampa General HospitalOTHER | 1 | Nov 10, 2015 | clinicaltrials |
| NCT00667394 | Tandutinib Plus Bevacizumab to Treat Recurrent Brain Tumors | completed | Phase 2 | 42 | National Cancer Institute (NCI)NIH | 1 | Nov 5, 2015 | clinicaltrials |
| NCT00846456 | Safe Study of Dendritic Cell (DC) Based Therapy Targeting Tumor Stem Cells in Glioblastoma | completed | Phase 1 / Phase 2 | 20 | Oslo University HospitalOTHER | 0 | Oct 20, 2015 | clinicaltrials |
| NCT00369590 | VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide | completed | Phase 2 | 58 | National Cancer Institute (NCI)NIH | 1 | Oct 2, 2015 | clinicaltrials |
| NCT01119599 | RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma | completed | Phase 1 | 22 | National Cancer Institute (NCI)NIH | 1 | Sep 29, 2015 | clinicaltrials |
| NCT01111097 | Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain Tumors | completed | Phase 1 | 15 | University of FloridaOTHER | 1 | Sep 22, 2015 | clinicaltrials |
| NCT00704808 | Post Marketing Surveillance: Newly Diagnosed Glioblastoma Multiforme Treated With Radiotherapy/Temozolomide and Adjuvant Temozolomide (Study P04739) | completed | — | 180 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Sep 9, 2015 | clinicaltrials |
| NCT00725010 | Temozolomide in Concomitant Radiochemotherapy Followed by Sequential Temozolomide Chemotherapy - Observational Program (Study P04816) | completed | — | 64 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Sep 9, 2015 | clinicaltrials |
| NCT01102595 | Neo-adjuvant Treatment With Temozolomide and Bevacizumab Previous to Temozolomide Plus Radiation Plus Bevacizumab Therapy in Unresectable Glioblastoma | completed | Phase 2 | 102 | Grupo Español de Investigación en NeurooncologíaOTHER | 1 | Aug 26, 2015 | clinicaltrials |
| NCT00087451 | Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED) | completed | Phase 1 | 11 | Merck Sharp & Dohme LLCINDUSTRY | 1 | Aug 19, 2015 | clinicaltrials |
| NCT02474966 | Effect of Deep TMS on the Permeability of the BBB in Patients With Glioblastoma Multiforme: a Pilot Study | completed | Phase 2 | 15 | University of Roma La SapienzaOTHER | 0 | Jun 18, 2015 | clinicaltrials |
| NCT01071837 | APG101 in Glioblastoma | completed | Phase 2 | 84 | Apogenix GmbHINDUSTRY | 2 | Jun 16, 2015 | clinicaltrials |
| NCT00112736 | Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma | completed | Phase 1 / Phase 2 | 69 | National Cancer Institute (NCI)NIH | 1 | Jun 15, 2015 | clinicaltrials |
| NCT00004146 | Carboxyamidotriazole + RT in Treating Patients Newly Diagnosed Supratentorial GBM | completed | Phase 2 | 55 | National Cancer Institute (NCI)NIH | 1 | May 8, 2015 | clinicaltrials |
| NCT00821080 | Vandetanib and Sirolimus in Patients With Recurrent Glioblastoma | completed | Phase 1 | 33 | Massachusetts General HospitalOTHER | 1 | May 1, 2015 | clinicaltrials |
| NCT00968240 | Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) | completed | Phase 1 | 30 | Northwell HealthOTHER | 1 | Apr 22, 2015 | clinicaltrials |
| NCT00049387 | Tipifarnib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma | completed | Phase 1 | 19 | National Cancer Institute (NCI)NIH | 1 | Apr 15, 2015 | clinicaltrials |
| NCT00979862 | Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma | completed | Phase 1 | 47 | National Cancer Institute (NCI)NIH | 1 | Apr 15, 2015 | clinicaltrials |
| NCT01604590 | Imaging Biomarkers of Tissue Microstructure and Vasculature as Predictors of Glioblastoma Multiforme | completed | — | 13 | Medical University of South CarolinaOTHER | 1 | Apr 13, 2015 | clinicaltrials |
| NCT00694837 | Study With Nelfinavir and Combined Radiochemotherapy for Glioblastoma | completed | Phase 1 | 6 | Maastricht Radiation OncologyOTHER | 1 | Apr 10, 2015 | clinicaltrials |
| NCT00943007 | Comparison of Standard Neuronavigation With Intraoperative Magnetic Resonance Imaging (MRI) for the Neurosurgical Treatment of Malignant Brain Tumors(RACING) | completed | N/A | 14 | Maastricht University Medical CenterOTHER | 2 | Apr 10, 2015 | clinicaltrials |
| NCT00996723 | Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) | completed | Phase 1 | 25 | St. Jude Children's Research HospitalOTHER | 1 | Apr 6, 2015 | clinicaltrials |
Data updated 23 days agoSource updated Sep 14, 2016source: clinicaltrials