Precursor Condition
Squamous Cell Intraepithelial Neoplasia
CI-CAN-00001551SIL · SINExplore in graph →
Precursor19 active trials
- NCIt
- C8334
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Precursor Condition
CI-CAN-00001551SIL · SINExplore in graph →
Clinical trials
115 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05372016 | Evaluate the Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females | completed | Phase 3 | 1,200 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Nov 24, 2023 | clinicaltrials |
| NCT02937155 | In the Era of the HPV Vaccine, What Are The Current HPV Subtypes Contributing to High Grade Cervical Dysplasia, Adenocarcinoma in Situ, and Early Cervical Cancer? | unknown | — | 100 | Sunnybrook Health Sciences CentreOTHER | 1 | Nov 22, 2023 |
| clinicaltrials |
| NCT02875561 | Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial Neoplasia | completed | N/A | 47 | University of Colorado, DenverOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT05051852 | HPV Viral Load in Predicting the Prognosis of LSIL | unknown | — | 1,000 | Fujian Maternity and Child Health HospitalOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT05282745 | A Multicenter Cohort Study of HPV Viral Load in Predicting the Postoperative Recurrence of HSIL | unknown | — | 4,000 | Fujian Maternity and Child Health HospitalOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT05283239 | Research About Impact of HPV Integration on the Prognosis of Women With Persistent HR-HPV Infection | unknown | — | 1,000 | Fujian Maternity and Child Health HospitalOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT03713229 | Seville Cohort of People Living With HIV at Risk for Anal Cancer(SeVIHanal) | enrolling by invitation | — | 3,000 | Hospitales Universitarios Virgen del RocíoOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT03180684 | Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3) | completed | Phase 2 | 33 | Inovio PharmaceuticalsINDUSTRY | 1 | Aug 25, 2023 | clinicaltrials |
| NCT03185013 | REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)(REVEAL 1) | completed | Phase 3 | 201 | Inovio PharmaceuticalsINDUSTRY | 19 | Jul 27, 2023 | clinicaltrials |
| NCT05120167 | Strategies for Endocervical Canal Investigation in Women With Abnormal Screening Cytology and Negative Colposcopy | completed | N/A | 288 | Cirbia Silva Campos TeixeiraOTHER | 1 | Jul 27, 2023 | clinicaltrials |
| NCT04952961 | Early Detection of Vulval CAncer Through Self-Examination (EDuCATE): Intervention Study | completed | N/A | 25 | University of ManchesterOTHER | 1 | Jun 22, 2023 | clinicaltrials |
| NCT05858021 | COrSIcA: Disease Measurement | unknown | — | 30 | David FinchOTHER | 0 | May 15, 2023 | clinicaltrials |
| NCT05835947 | Anal Cancer Risk In Women | unknown | — | 200 | Imperial College LondonOTHER | 1 | Apr 28, 2023 | clinicaltrials |
| NCT05835960 | Anal Intraepithelial Neoplasia and Anal Squamous Cell Carcinoma | unknown | — | 20 | Imperial College LondonOTHER | 1 | Apr 28, 2023 | clinicaltrials |
| NCT05808816 | "Lactobacillus Crispatus M247, LSIL and Microbiota" | unknown | Phase 4 | 90 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Apr 11, 2023 | clinicaltrials |
| NCT05745597 | Prognostic Study of HPV Virus Integration in Women With HSIL | unknown | — | 1,000 | Fujian Maternity and Child Health HospitalOTHER | 1 | Feb 27, 2023 | clinicaltrials |
| NCT04704908 | Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls (54m) | unknown | — | 979 | Jun ZhangOTHER | 1 | Jan 26, 2023 | clinicaltrials |
| NCT04969445 | The Durability of Protection Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female | unknown | — | 647 | Jun ZhangOTHER | 1 | Jan 26, 2023 | clinicaltrials |
| NCT05045755 | The Durability of Protection and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female | unknown | — | 1,339 | Jun ZhangOTHER | 1 | Jan 26, 2023 | clinicaltrials |
| NCT05580341 | Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9 | unknown | Phase 3 | 1,200 | Shanghai Zerun Biotechnology Co.,LtdINDUSTRY | 1 | Oct 28, 2022 | clinicaltrials |
| NCT05536843 | Clinical, Translational and Biomarker-Based Female Genital HPV Induced Dysplasia and Cancer Screening Study Using Cf-HPV-DNA Blood Tests(TTMV HPV DNA) | unknown | — | 500 | University of Mississippi Medical CenterOTHER | 0 | Sep 13, 2022 | clinicaltrials |
| NCT05426148 | Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female | completed | Phase 4 | 540 | Xiamen Innovax Biotech Co., LtdINDUSTRY | 1 | Jun 29, 2022 | clinicaltrials |
| NCT02503111 | The HPV-SAVE Study Team: HPV Screening and Vaccine Evaluation in Men Who Have Sex With Men(HPV-SAVE) | terminated | N/A | 71 | University Health Network, TorontoOTHER | 1 | Jun 13, 2022 | clinicaltrials |
| NCT03947775 | HPV-SAVE_Merck_Sub-Study for Preventing Recurrence of HSIL | unknown | Phase 2 | 228 | University Health Network, TorontoOTHER | 1 | Jun 13, 2022 | clinicaltrials |
| NCT03113942 | Study of Pomalidomide in Anal Cancer Precursors(SPACE) | unknown | Phase 2 | 26 | Kirby InstituteOTHER_GOV | 1 | Mar 31, 2022 | clinicaltrials |
| NCT04425291 | Evaluate the Immunogenicity and Safety of 4-valent and 9-valent HPV Recombinant Vaccine in Chinese Healthy Females | completed | Phase 3 | 1,680 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Feb 25, 2022 | clinicaltrials |
| NCT05210348 | Clinical Evaluation of Detection of High Risk HPV in Urine(Urine-hrHPV) | unknown | — | 1,000 | Peking University People's HospitalOTHER | 1 | Jan 27, 2022 | clinicaltrials |
| NCT03100045 | Intra-Anally Administered Artesunate in Patients With High-Grade Anal Intraepithelial Neoplasia (AIN 2/3)(ART-AIN) | completed | Phase 1 | 18 | Johns Hopkins UniversityOTHER | 1 | Nov 3, 2021 | clinicaltrials |
| NCT04109573 | Function Following Laser for Anal Intraepithelial Neoplasia (FLAN)(FLAN) | unknown | N/A | 20 | Homerton University Hospital NHS Foundation TrustOTHER | 1 | Aug 31, 2021 | clinicaltrials |
| NCT01861535 | Primary Imiquimod Treatment Versus Surgery for Vulvar Intraepithelial Neoplasia(PITVIN) | completed | Phase 3 | 110 | Medical University of GrazOTHER | 1 | Apr 14, 2021 | clinicaltrials |
| NCT03937791 | Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions | terminated | Phase 2 | 1 | National Cancer Institute (NCI)NIH | 1 | Apr 13, 2021 | clinicaltrials |
| NCT02087384 | HPV (Human Papilloma Virus) Vaccination After Treatment of Anal Intraepithelial Neoplasia (AIN)(VACCAIN-P) | completed | Phase 4 | 126 | Prof. Jan PrinsOTHER | 1 | Mar 5, 2021 | clinicaltrials |
| NCT03697226 | Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection. | completed | Phase 1 | 8 | Antiva BiosciencesINDUSTRY | 1 | Jan 13, 2021 | clinicaltrials |
| NCT00503581 | Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia | terminated | Phase 2 | 9 | Gynecologic Oncology GroupNETWORK | 1 | Nov 3, 2020 | clinicaltrials |
| NCT01550783 | Home-Based or Clinic-Based Human Papillomavirus (HPV) Screening | completed | N/A | 1,335 | University of WashingtonOTHER | 1 | Jul 31, 2020 | clinicaltrials |
| NCT01735006 | Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent（Type 16/18 ）Vaccine | completed | Phase 3 | 7,372 | Xiamen UniversityOTHER | 1 | Feb 24, 2020 | clinicaltrials |
| NCT03676101 | Evaluate the Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females | completed | Phase 1 | 90 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Jan 22, 2020 | clinicaltrials |
| NCT03677960 | Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection | terminated | Phase 1 | 6 | Antiva BiosciencesINDUSTRY | 2 | Jul 24, 2019 | clinicaltrials |
| NCT03239223 | Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection | completed | Phase 1 | 16 | Antiva BiosciencesINDUSTRY | 2 | Jul 10, 2019 | clinicaltrials |
| NCT03202992 | Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection | completed | Phase 1 | 57 | Antiva BiosciencesINDUSTRY | 2 | Feb 7, 2019 | clinicaltrials |
| NCT03206255 | Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls | completed | — | 940 | Jun ZhangOTHER | 1 | Jan 4, 2019 | clinicaltrials |
| NCT01651949 | Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003) | completed | Phase 3 | 2,520 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Nov 27, 2018 | clinicaltrials |
| NCT03409471 | HPV Test of Urine and Self Collected Vaginal Samples for Cervical Cancer Screening Study | unknown | — | 300 | Korea University Guro HospitalOTHER | 1 | Aug 24, 2018 | clinicaltrials |
| NCT02562508 | A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls | completed | Phase 3 | 979 | Jun ZhangOTHER | 1 | Aug 16, 2018 | clinicaltrials |
| NCT03469531 | Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer | unknown | Phase 2 | 100 | Zhujiang HospitalOTHER | 1 | Aug 13, 2018 | clinicaltrials |
| NCT01923116 | Therapeutic HPV-16 Vaccination for the Treatment of Anal Dysplasia(VACCAIN-T) | completed | Phase 1 / Phase 2 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Mar 15, 2018 | clinicaltrials |
| NCT03357991 | E6/E7 mRNA Performance to Detect HSIL and Cost-effectiveness Analysis of This Screening Strategy in HIV + MSM(ELAVI-67) | unknown | — | 355 | Hospital Universitari de BellvitgeOTHER | 1 | Dec 7, 2017 | clinicaltrials |
| NCT03302858 | A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand | unknown | Phase 2 | 70 | Stephen E. GoldstoneOTHER | 1 | Oct 5, 2017 | clinicaltrials |
| NCT02199327 | Topical Interferon Alfa 2b and Mitomycin C in Conjunctival-Corneal Intraepithelial Neoplasia | completed | Phase 4 | 18 | Coordinación de Investigación en Salud, MexicoOTHER_GOV | 1 | Aug 8, 2017 | clinicaltrials |
| NCT02223975 | Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease(Vulval VS) | suspended | — | 200 | Gloucestershire Hospitals NHS Foundation TrustOTHER | 1 | Aug 4, 2017 | clinicaltrials |
Data updated 23 days agoSource updated Nov 24, 2023source: clinicaltrials