Precursor Condition
Squamous Cell Intraepithelial Neoplasia
CI-CAN-00001551SIL · SINExplore in graph →
Precursor19 active trials
- NCIt
- C8334
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Precursor Condition
CI-CAN-00001551SIL · SINExplore in graph →
Clinical trials
115 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03603808 | VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions | completed | Phase 2 | 44 | AIDS Malignancy ConsortiumNETWORK | 2 | Jul 8, 2026 | clinicaltrials |
| NCT06971276 | Assessing the Utility of Plasma ctHPVDNA for Anal Cancer Screening(SCAN-LITE) | completed | — | 104 | Massachusetts Eye and Ear InfirmaryOTHER | 1 | Apr 28, 2026 |
| clinicaltrials |
| NCT03284866 | HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV(COVENANT) | completed | Phase 3 | 536 | AIDS Malignancy ConsortiumNETWORK | 5 | Jan 28, 2026 | clinicaltrials |
| NCT02534233 | Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Epithelium(ColdPlay2) | completed | N/A | 58 | Johns Hopkins UniversityOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT05104099 | Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia(PhotodiVIN) | completed | Phase 2 | 17 | Institut de Cancérologie de LorraineOTHER | 1 | Jul 24, 2025 | clinicaltrials |
| NCT02059499 | Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions | completed | Phase 3 | 91 | AIDS Malignancy ConsortiumNETWORK | 2 | Jul 23, 2025 | clinicaltrials |
| NCT03196180 | Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia | completed | Early Phase 1 | 13 | National Cancer Institute (NCI)NIH | 1 | Apr 8, 2025 | clinicaltrials |
| NCT04276935 | Development of a Health-Related Symptom Index for Participants With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions | completed | — | 20 | AIDS Malignancy ConsortiumNETWORK | 1 | Mar 7, 2025 | clinicaltrials |
| NCT05717621 | Clinical Trial With Local Decitabine Treatment of HPV-Induced VIN Grade 2/3 (DelVIN)(DelVIN) | completed | Phase 1 | 29 | ViMREX GmbHINDUSTRY | 1 | Feb 11, 2025 | clinicaltrials |
| NCT03792516 | Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3)(ART-VIN) | completed | Phase 1 | 15 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Dec 4, 2024 | clinicaltrials |
| NCT03721978 | REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) | completed | Phase 3 | 203 | Inovio PharmaceuticalsINDUSTRY | 10 | Oct 17, 2024 | clinicaltrials |
| NCT06297187 | Cavitronic Ultrasonic Surgical Aspiration (CUSA) Women's Health Study | completed | — | 56 | Integra LifeSciences CorporationINDUSTRY | 1 | Sep 19, 2024 | clinicaltrials |
| NCT02135419 | Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions(ANCHOR) | completed | Phase 3 | 4,446 | AIDS Malignancy ConsortiumNETWORK | 2 | Jul 26, 2024 | clinicaltrials |
| NCT04055142 | Clinical Trial for Evaluating the Efficacy and Safety of Electrocoagulation vs Topic Sinecatechins vs Topic Cidofovir Within the Treatment to High-grade Anal Intraepithelial Neoplasia in HIV Homosexual Males(TreatAIN) | completed | Phase 3 | 108 | Hospital Universitari Vall d'Hebron Research InstituteOTHER | 1 | Jul 10, 2024 | clinicaltrials |
| NCT05372016 | Evaluate the Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females | completed | Phase 3 | 1,200 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Nov 24, 2023 | clinicaltrials |
| NCT02875561 | Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial Neoplasia | completed | N/A | 47 | University of Colorado, DenverOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT03180684 | Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3) | completed | Phase 2 | 33 | Inovio PharmaceuticalsINDUSTRY | 1 | Aug 25, 2023 | clinicaltrials |
| NCT03185013 | REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)(REVEAL 1) | completed | Phase 3 | 201 | Inovio PharmaceuticalsINDUSTRY | 19 | Jul 27, 2023 | clinicaltrials |
| NCT05120167 | Strategies for Endocervical Canal Investigation in Women With Abnormal Screening Cytology and Negative Colposcopy | completed | N/A | 288 | Cirbia Silva Campos TeixeiraOTHER | 1 | Jul 27, 2023 | clinicaltrials |
| NCT04952961 | Early Detection of Vulval CAncer Through Self-Examination (EDuCATE): Intervention Study | completed | N/A | 25 | University of ManchesterOTHER | 1 | Jun 22, 2023 | clinicaltrials |
| NCT05426148 | Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female | completed | Phase 4 | 540 | Xiamen Innovax Biotech Co., LtdINDUSTRY | 1 | Jun 29, 2022 | clinicaltrials |
| NCT04425291 | Evaluate the Immunogenicity and Safety of 4-valent and 9-valent HPV Recombinant Vaccine in Chinese Healthy Females | completed | Phase 3 | 1,680 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Feb 25, 2022 | clinicaltrials |
| NCT03100045 | Intra-Anally Administered Artesunate in Patients With High-Grade Anal Intraepithelial Neoplasia (AIN 2/3)(ART-AIN) | completed | Phase 1 | 18 | Johns Hopkins UniversityOTHER | 1 | Nov 3, 2021 | clinicaltrials |
| NCT01861535 | Primary Imiquimod Treatment Versus Surgery for Vulvar Intraepithelial Neoplasia(PITVIN) | completed | Phase 3 | 110 | Medical University of GrazOTHER | 1 | Apr 14, 2021 | clinicaltrials |
| NCT02087384 | HPV (Human Papilloma Virus) Vaccination After Treatment of Anal Intraepithelial Neoplasia (AIN)(VACCAIN-P) | completed | Phase 4 | 126 | Prof. Jan PrinsOTHER | 1 | Mar 5, 2021 | clinicaltrials |
| NCT03697226 | Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection. | completed | Phase 1 | 8 | Antiva BiosciencesINDUSTRY | 1 | Jan 13, 2021 | clinicaltrials |
| NCT01550783 | Home-Based or Clinic-Based Human Papillomavirus (HPV) Screening | completed | N/A | 1,335 | University of WashingtonOTHER | 1 | Jul 31, 2020 | clinicaltrials |
| NCT01735006 | Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent（Type 16/18 ）Vaccine | completed | Phase 3 | 7,372 | Xiamen UniversityOTHER | 1 | Feb 24, 2020 | clinicaltrials |
| NCT03676101 | Evaluate the Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females | completed | Phase 1 | 90 | Shanghai Bovax Biotechnology Co., Ltd.INDUSTRY | 1 | Jan 22, 2020 | clinicaltrials |
| NCT03239223 | Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection | completed | Phase 1 | 16 | Antiva BiosciencesINDUSTRY | 2 | Jul 10, 2019 | clinicaltrials |
| NCT03202992 | Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection | completed | Phase 1 | 57 | Antiva BiosciencesINDUSTRY | 2 | Feb 7, 2019 | clinicaltrials |
| NCT03206255 | Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls | completed | — | 940 | Jun ZhangOTHER | 1 | Jan 4, 2019 | clinicaltrials |
| NCT01651949 | Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003) | completed | Phase 3 | 2,520 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Nov 27, 2018 | clinicaltrials |
| NCT02562508 | A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls | completed | Phase 3 | 979 | Jun ZhangOTHER | 1 | Aug 16, 2018 | clinicaltrials |
| NCT01923116 | Therapeutic HPV-16 Vaccination for the Treatment of Anal Dysplasia(VACCAIN-T) | completed | Phase 1 / Phase 2 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Mar 15, 2018 | clinicaltrials |
| NCT02199327 | Topical Interferon Alfa 2b and Mitomycin C in Conjunctival-Corneal Intraepithelial Neoplasia | completed | Phase 4 | 18 | Coordinación de Investigación en Salud, MexicoOTHER_GOV | 1 | Aug 8, 2017 | clinicaltrials |
| NCT01637298 | Biomarkers to Detect Anal Intraepithelial Neoplasia in Thai Men Who Have Sex With Men | completed | — | 450 | Thai Red Cross AIDS Research CentreOTHER | 0 | May 9, 2017 | clinicaltrials |
| NCT02189161 | A Safety and Tolerability of Circumferential Anal Canal Radiofrequency Ablation For Anal Intraepithelial Neoplasia | completed | N/A | 10 | Medtronic - MITGINDUSTRY | 1 | Jul 14, 2016 | clinicaltrials |
| NCT02418494 | Health-Related Symptom Questionnaires in Measuring Quality of Life in HIV-Infected Participants Treated or Monitored for Anal Lesions | completed | — | 85 | AIDS Malignancy ConsortiumNETWORK | 1 | Jun 9, 2016 | clinicaltrials |
| NCT01366742 | Natural History of HPV From Infection to Neoplasia in Adolescents and Young Women | completed | — | 900 | University of California, Los AngelesOTHER | 1 | May 17, 2016 | clinicaltrials |
| NCT00201370 | A Multi-center Survey of HPV in Cervical Intraepithelial Neoplasia (CIN) With Longitudinal Follow-up of LSIL Cases | completed | — | 1,000 | National Health Research Institutes, TaiwanOTHER | 1 | Mar 25, 2016 | clinicaltrials |
| NCT00188292 | Screening for HIV-Associated Anal Cancer(TRACE) | completed | — | 401 | University Health Network, TorontoOTHER | 1 | Mar 8, 2016 | clinicaltrials |
| NCT01986725 | The Impact of the "WOMAN-PRO II Program" on Patients With Vulvar Neoplasia to Minimize Post-surgical Symptom Prevalence(WOMAN-PROII) | completed | Phase 2 | 45 | St.Gallen University of Applied SciencesOTHER | 1 | Jan 7, 2016 | clinicaltrials |
| NCT01676792 | SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous Condyloma | completed | Early Phase 1 | 29 | National Cheng-Kung University HospitalOTHER | 1 | Apr 22, 2014 | clinicaltrials |
| NCT00091130 | SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells | completed | Phase 2 | 139 | National Cancer Institute (NCI)NIH | 1 | Jun 3, 2013 | clinicaltrials |
Data updated 23 days agoSource updated Jul 8, 2026source: clinicaltrials