Hematologic Malignancy
Smoldering Multiple Myeloma
CI-CAN-00003983Explore in graph →
Hematologic34 active trials
- NCIt
- C7149
- MeSH
- D000075122
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Hematologic Malignancy
CI-CAN-00003983Explore in graph →
Clinical trials
85 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (11)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06768489 | A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide for Multiple Myeloma, Newly Diagnosed AL Amyloidosis, and High-risk Smoldering Multiple Myeloma or JNJ-79635322 in Combination With Pomalidomide for Multiple Myeloma | recruiting | Phase 1 | 276 | Janssen Research & Development, LLCINDUSTRY | 5 | Sep 25, 2026 | clinicaltrials |
| NCT05283993 | A Cohort Study of Plasma Cell Disorders (PCDs) in PKUFH | recruiting | — | 2,000 | Peking University First HospitalOTHER | 1 |
| Sep 16, 2026 |
| clinicaltrials |
| NCT03937635 | Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma | recruiting | Phase 3 | 288 | ECOG-ACRIN Cancer Research GroupNETWORK | 2 | Aug 19, 2026 | clinicaltrials |
| NCT05469893 | Immuno-PRISM (PRecision Intervention Smoldering Myeloma) | recruiting | Phase 2 | 52 | Irene Ghobrial, MDOTHER | 1 | Jul 16, 2026 | clinicaltrials |
| NCT06644625 | CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study | recruiting | — | 1,665 | Wake Forest University Health SciencesOTHER | 1 | Jul 13, 2026 | clinicaltrials |
| NCT06140524 | A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma(LINKER-MGUS1) | recruiting | Phase 2 | 116 | Regeneron PharmaceuticalsINDUSTRY | 7 | Jul 8, 2026 | clinicaltrials |
| NCT04776395 | Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma | recruiting | Phase 2 | 68 | Emory UniversityOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT02269592 | Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome | recruiting | — | 10,000 | Dana-Farber Cancer InstituteOTHER | 1 | May 7, 2026 | clinicaltrials |
| NCT07446777 | FAST-M: Prolonged Overnight Fasting and Mediterranean Dietary Intervention for Patients With Multiple Myeloma or Its Precursor Disease(FAST-M) | recruiting | N/A | 120 | University of MiamiOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT07214324 | Integrative Multi-omics Analysis to Predict Monoclonal Gammopathies Clinical Evolution(PNRR-2022-1237) | recruiting | — | 60 | Azienda USL Reggio Emilia - IRCCSOTHER_GOV | 1 | Apr 23, 2026 | clinicaltrials |
| NCT02726750 | Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma | recruiting | — | 200 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT05640843 | A Study Comparing a Plant-Based Diet With Supplements and Placebo in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM) | recruiting | N/A | 180 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT06383143 | Promoting Diagnosis and Management of AL in Italy (ProDigALIty)(ProDigALIty) | recruiting | — | 760 | Fondazione IRCCS Policlinico San Matteo di PaviaOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT05136807 | Quality of Life in Patients With Asymptomatic Monoclonal Gammopathies | recruiting | — | 400 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 15, 2026 | clinicaltrials |
| NCT05361694 | Two Biologically and Clinically Distinct Entities: Progressive Versus Stable Multiple Myeloma (MM) Precursor Conditions(TRANSFORMM) | recruiting | — | 1,000 | University of MiamiOTHER | 1 | Apr 9, 2026 | clinicaltrials |
| NCT07069751 | A Prospective Multicenter Study of the Effects of Plant-based Diets on Gut Microbiome and Derived Metabolites in Patients Affected by Smoldering Multiple Myeloma(HiFi-MM) | recruiting | N/A | 62 | Ciceri FabioOTHER | 1 | Apr 3, 2026 | clinicaltrials |
| NCT06212323 | Smoldering Myeloma High-Risk Patient Observation and Longitudinal Insight Trial(SPOTLIGHT) | recruiting | — | 100 | University of UtahOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT06237803 | European Myeloma Network (EMN) Sample Project(EMN36) | recruiting | — | 6,000 | European Myeloma Network B.V.NETWORK | 10 | Dec 3, 2025 | clinicaltrials |
| NCT05312255 | Non-chemotherapeutic Interventions for the Improvement of Quality of Life and Immune Function in Patients With Multiple Myeloma | recruiting | N/A | 175 | Roswell Park Cancer InstituteOTHER | 1 | Dec 1, 2025 | clinicaltrials |
| NCT03717844 | Registry for Adults With Plasma Cell Disorders (PCD's) | recruiting | — | 2,000 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT06055894 | A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS) | recruiting | N/A | 200 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Nov 13, 2025 | clinicaltrials |
| NCT06365060 | Screening for AL Amyloidosis in Smoldering Multiple Myeloma | recruiting | — | 400 | Tufts Medical CenterOTHER | 1 | Aug 6, 2025 | clinicaltrials |
| NCT05841550 | The TG01 Study With TG01/QS-21 Vaccine in Patients With High-risk Smouldering Multiple Myeloma and Multiple Myeloma | recruiting | Phase 1 / Phase 2 | 20 | Oslo University HospitalOTHER | 1 | Aug 5, 2025 | clinicaltrials |
| NCT06762769 | Isatuximab and Iberdomide as Immunotherapy for High Risk in Smouldering Myeloma(MODIFY) | recruiting | Phase 2 | 63 | University College, LondonOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT06895291 | Whole Body MRI in Oncology(ONCO-MRI) | recruiting | — | 1,000 | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSOTHER | 1 | Mar 30, 2025 | clinicaltrials |
| NCT05597345 | Selinexor for the Treatment of Intermediate and High-Risk Smoldering Multiple Myeloma | recruiting | Phase 2 | 15 | University of RochesterOTHER | 1 | Feb 10, 2025 | clinicaltrials |
Data updated 4 days agoSource updated Sep 25, 2026source: clinicaltrials