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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
13 stopped studies mapped to Smoldering Multiple Myeloma and descendants · 92% state a reason
Over the 13 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT05288062 | Immunomodulatory Drugs (Lenalidomide With or Without Pomalidomide) in Combination With a… | Phase 2 | terminated | Mar 18, 2022 | Mayo Clinic | slow accrual | Enrollment / accrual |
| NCT03591614 | Dendritic Cell DKK1 Vaccine for Monoclonal Gammopathy and Stable or Smoldering Myeloma | Early Phase 1 | withdrawn | Jul 19, 2018 | Case Comprehensive Cancer Center | PI left institution | Investigator |
| NCT01838369 | A Phase II Study of BI-505 in Smoldering Multiple Myeloma | Phase 2 | terminated | Apr 24, 2013 | BioInvent International AB | Sponsor's decision | Sponsor / business decision |
| NCT03850522 | PD-L1 Peptide Vaccination in High Risk Smoldering Multiple Myeloma | Phase 2 | terminated | Feb 21, 2019 | Lene Meldgaard Knudsen | Insufficient recruitment within planned enrolmentperiod. | Enrollment / accrual |
| NCT01079429 | Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma…(GENOMGUS) | — | terminated | Mar 3, 2010 | Rennes University Hospital | sponsor and investigator 's decision | Investigator |
| NCT01109407 | Natural History Study of Monoclonal Gammopathy of Undetermined Significance (MGUS) and… | — | terminated | Apr 23, 2010 | National Cancer Institute (NCI) | PI Left before primary outcome was established | Investigator |
| NCT02784483 | Pilot Study Of Anti-Programmed Death Ligand-1 (Anti-PD-L1, Atezolizumab) In Asymptomatic… | Phase 1 | terminated | May 27, 2016 | Yale University | Based on FDA requirements | Other (stated, no rule matched) |
| NCT01571726 | Imaging Studies and the Development of Multiple Myeloma | Phase 2 | withdrawn | Apr 5, 2012 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01248455 | A Phase II Trial of Anti-KIR in Smoldering Multiple Myeloma | Phase 2 | terminated | Nov 25, 2010 | National Cancer Institute (NCI) | Lack of patients meeting the defined primary obj. (50% decline in M-protein). | Other (stated, no rule matched) |
| NCT03952832 | Leflunomide in Treating Patients With High-Risk Smoldering Multiple Myeloma | Phase 2 | withdrawn | May 16, 2019 | City of Hope Medical Center | Budget issues | Funding |
| NCT00503763 | Efficacy and Safety of Statin on the Course of Progressive Smoldering Multiple Myeloma(PSMMSS) | Phase 2 | withdrawn | Jul 19, 2007 | Meir Medical Center | We found out that there is another study on the same issue | Other (stated, no rule matched) |
| NCT02353572 | Melphalan and Bortezomib Prior to Autologous Stem Cell Transplant in Treating Patients… | Phase 1 / Phase 2 | terminated | Feb 2, 2015 | University of Colorado, Denver | Principle investigator left the institution | Investigator |
| NCT00899353 | Prevention of Disease Progression in Early Stage Indolent B Cell Malignancies. (SMM) | Phase 2 | terminated | May 12, 2009 | Marshall University | Original Principal Investigator left the institution. | Investigator |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 2 days agoSource updated Sep 28, 2026source: clinicaltrials