Subtype
Rectal Neoplasm
CI-CAN-00006564Explore in graph →
Non-malignant433 active trials1 approved drugs5 evidence items
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Subtype
CI-CAN-00006564Explore in graph →
Clinical trials
1,772 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03127007 | Safety and Efficacy of Atezolizumab Combined to Preoperative Radio-chemotherapy in Localized Rectal Cancer(R-IMMUNE) | completed | Phase 1 / Phase 2 | 45 | Grand Hôpital de CharleroiOTHER | 1 | Jan 22, 2025 | clinicaltrials |
| NCT06108596 | Evaluation of the Efficacy and Safety of Interleucin-2 Combined With PD-1 Monoclonal Antibody and CAPOX in Preoperative Neoadjuvant Therapy for Mid-low Locally Advanced Rectal Cancer - a Single-center, Single-arm, Open-label Clinical Trail(PICS) | completed | Phase 2 | 33 | The First Affiliated Hospital with Nanjing Medical University |
| 1 |
| Jan 21, 2025 |
| clinicaltrials |
| NCT04518280 | Short-course Radiotherapy Based TNT Combined With PD-1 Inhibitor for Locally Advanced Rectal Cancer(TORCH) | completed | Phase 2 | 130 | Fudan UniversityOTHER | 1 | Jan 17, 2025 | clinicaltrials |
| NCT02861300 | CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer | completed | Phase 1 / Phase 2 | 50 | David Bajor, MDOTHER | 1 | Dec 19, 2024 | clinicaltrials |
| NCT04028479 | The Registry of Oncology Outcomes Associated With Testing and Treatment(ROOT) | completed | — | 167 | Taproot HealthINDUSTRY | 1 | Dec 18, 2024 | clinicaltrials |
| NCT01461525 | Comparison of Sphincter Preservation Surgery and Abdominoperineal Resection (APR): Prospective Clinical Trial(ASPIRE) | completed | N/A | 342 | Seoul National University HospitalOTHER | 1 | Dec 5, 2024 | clinicaltrials |
| NCT03828318 | Impact of a Patient-Centered Program for Low Anterior Resection Syndrome a Multicenter Randomized Controlled Trial | completed | N/A | 160 | Jewish General HospitalOTHER | 2 | Nov 29, 2024 | clinicaltrials |
| NCT03436563 | M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability | completed | Phase 1 / Phase 2 | 4 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 27, 2024 | clinicaltrials |
| NCT05461248 | Stoma Discharge Reinfusion After Sphincter Preservation for Middle and Low Rectal Cancer | completed | N/A | 60 | The First Hospital of Jilin UniversityOTHER | 1 | Nov 22, 2024 | clinicaltrials |
| NCT00807911 | Adjuvant Chemotherapy After Preoperative Chemoradiotherapy to Treat Rectal Cancer | completed | Phase 2 | 322 | Asan Medical CenterOTHER | 1 | Oct 23, 2024 | clinicaltrials |
| NCT04679597 | Total Neoadjuvant Therapy Versus Standard Therapy of Locally Advanced Rectal Cancer With High Risk Factors for Failure | completed | — | 161 | Institute of Oncology LjubljanaOTHER | 0 | Oct 17, 2024 | clinicaltrials |
| NCT05985239 | Virtual Ileostomy Versus Diverting Ileostomy | completed | — | 612 | fan liOTHER | 1 | Oct 15, 2024 | clinicaltrials |
| NCT03251378 | A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors and Colorectal, and Breast Cancers | completed | Phase 1 | 129 | Hutchison Medipharma LimitedINDUSTRY | 1 | Sep 25, 2024 | clinicaltrials |
| NCT05745909 | Trial Comparing Loop Ileostomy Versus Loop Transverse Colostomy(LIVELOC) | completed | N/A | 150 | Republican Clinical Oncological Dispensary, Ministry of Health of the Republic of BashkortostanOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT02431676 | Survivorship Promotion In Reducing IGF-1 Trial(SPIRIT) | completed | Phase 2 | 121 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Aug 28, 2024 | clinicaltrials |
| NCT05086627 | Short-course Radiotherapy Followed by Tislelizumab + CapeOX in the Treatment for Locally Advanced Rectal Cancer | completed | Phase 2 | 118 | Hebei Medical University Fourth HospitalOTHER | 1 | Aug 22, 2024 | clinicaltrials |
| NCT00297791 | COLOR II: Laparoscopic Versus Open Rectal Cancer Removal(COLORII) | completed | Phase 3 | 1,044 | Nova Scotia Health AuthorityOTHER | 9 | Aug 21, 2024 | clinicaltrials |
| NCT05130060 | A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer | completed | Phase 1 | 15 | Mayo ClinicOTHER | 1 | Aug 14, 2024 | clinicaltrials |
| NCT00788957 | Panitumumab Combination Study With Rilotumumab or Ganitumab in Wild-type Kirsten Rat Sarcoma Virus Oncogene Homolog (KRAS) Metastatic Colorectal Cancer (mCRC) | completed | Phase 1 / Phase 2 | 177 | NantBioScience, Inc.INDUSTRY | 0 | Aug 7, 2024 | clinicaltrials |
| NCT03133286 | Radiotherapy Assessments During Intervention ANd Treatment (RADIANT)(RADIANT) | completed | — | 16 | DxTerity DiagnosticsINDUSTRY | 1 | Aug 7, 2024 | clinicaltrials |
| NCT06542354 | Prehabilitation During Neoadjuvant Chemoradiotherapy for Rectal Cancer | completed | N/A | 108 | Fudan UniversityOTHER | 1 | Aug 7, 2024 | clinicaltrials |
| NCT04938336 | Evaluation of a Decision Aid Tool in Rectal Cancer patiënts | completed | — | 70 | University Hospital, GhentOTHER | 1 | Jul 11, 2024 | clinicaltrials |
| NCT06104579 | Concordance Between Monitoring Systems for Organ/Space Surgical Site Infections in Rectal Surgery | completed | — | 11,367 | Hospital de GranollersOTHER | 1 | May 31, 2024 | clinicaltrials |
| NCT06435975 | Physical Activity in Rectal Cancer Survivors | completed | N/A | 20 | Abramson Cancer Center at Penn MedicineOTHER | 1 | May 30, 2024 | clinicaltrials |
| NCT04357587 | Safety and Feasibility of PD-1 Blockade in the Treatment of dMMR or MSI-H Rectal Cancer | completed | Phase 1 | 6 | Case Comprehensive Cancer CenterOTHER | 1 | May 29, 2024 | clinicaltrials |
| NCT01345175 | Rifaximin and Placebo in the Treatment of Bowel Dysfunction After Anterior Resection for Rectal Cancer | completed | Phase 3 | 69 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 14, 2024 | clinicaltrials |
| NCT06382415 | Organ/Space Surgical Site Infection and Recurrence and Survival in Rectal Cancer Surgery(VINCat_PDO_2) | completed | — | 3,826 | Hospital de GranollersOTHER | 1 | May 13, 2024 | clinicaltrials |
| NCT06405308 | Robotic Natural Orifice Specimen Extraction Surgery Versus Robotic Transabdominal Specimen Extraction Surgery for Early-Stage Rectal Cancer | completed | — | 636 | Taiyuan LiOTHER | 1 | May 13, 2024 | clinicaltrials |
| NCT06404554 | A Prediction Model of Anastomotic Stricture After Rectal Cancer | completed | — | 1,542 | Northern Jiangsu People's HospitalOTHER | 1 | May 8, 2024 | clinicaltrials |
| NCT02022553 | Procedure RACHEL in Complex Treatment of Rectal Cancer(RACHEL) | completed | N/A | 52 | Voronezh N.N. Burdenko State Medical AcademyOTHER | 1 | May 6, 2024 | clinicaltrials |
| NCT02132858 | Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation | completed | — | 43 | Fox Chase Cancer CenterOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT06396975 | Comparison of Short-term Outcomes of Robotic and Laparoscopic Surgery in Patients With Different Body Mass Index for Mid and Low Rectal Cancer | completed | — | 1,413 | Daorong WangOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT06397053 | Comparison of Robotic Versus Laparoscopic Surgery for Visceral Obesity in Mid-Low Rectal Cancer: A Propensity-Matched Analysis | completed | — | 242 | Daorong WangOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT04205955 | Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survivors | completed | Phase 2 | 95 | SWOG Cancer Research NetworkNETWORK | 2 | May 1, 2024 | clinicaltrials |
| NCT06391060 | Gender Differences in Robotic Surgery for Rectal Cancer: a Retrospective Study | completed | — | 155 | Daorong WangOTHER | 1 | Apr 30, 2024 | clinicaltrials |
| NCT04124601 | Neoadjuvant Chemoradiotherapy With Sequential Ipilimumab and Nivolumab in Rectal Cancer(CHINOREC) | completed | Phase 2 | 80 | Johannes Laengle, MD, PhDOTHER | 1 | Apr 23, 2024 | clinicaltrials |
| NCT06376227 | Robotic-Assisted or Laparoscopic Radical Resection for Rectal Cancer With or Without Left Colic Artery Preservation | completed | — | 1,164 | Northern Jiangsu People's HospitalOTHER | 1 | Apr 22, 2024 | clinicaltrials |
| NCT01972373 | Visualization of Rectal Cancer During Endoscopy, Using a Fluorescent Tracer(RAPIDO-TRACT) | completed | Phase 1 | 30 | University Medical Center GroningenOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT04638036 | Fluorescence Molecular Endoscopy and Molecular Fluorescence-guided Surgery in Locally Advanced Rectal Cancer(TRACT-II) | completed | Phase 1 | 11 | University Medical Center GroningenOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT03317119 | Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery | completed | Phase 1 | 26 | City of Hope Medical CenterOTHER | 1 | Apr 8, 2024 | clinicaltrials |
| NCT05293054 | Healing of Rectal Anastomosis Sealed With a Concentrate Derived From the Patient's Blood, After Rectal Cancer Surgery(OBANORES) | completed | — | 50 | University of AarhusOTHER | 1 | Mar 27, 2024 | clinicaltrials |
| NCT06271629 | Impact of Quality of Life in the Patients With Sleep Disturbance From Low Anterior Resection Syndrome in Advanced Rectal Cancer Patients | completed | — | 100 | Seoul National University HospitalOTHER | 1 | Mar 26, 2024 | clinicaltrials |
| NCT06314737 | Assessment of Efficacy of Neoadjuvant Therapy in Locally Advanced Rectal Cancer | completed | — | 3,515 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Mar 18, 2024 | clinicaltrials |
| NCT05933785 | the Value of Transanal Endoscopic ISR | completed | — | 260 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Mar 7, 2024 | clinicaltrials |
| NCT06293612 | Constructing a Multimodal Imaging System to Predict the Risk of Heterochronous Metastasis of Rectal Cancer(MIS-MRC) | completed | — | 302 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Mar 5, 2024 | clinicaltrials |
| NCT00019006 | Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT00020267 | Vaccine Therapy in Treating Patients With Metastatic Cancer | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT00407654 | VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer | completed | Phase 2 | 75 | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT05498506 | Multiple Firings in Double-stapled Colorectal Anastomosis | completed | — | 350 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Feb 26, 2024 | clinicaltrials |
Data updated 22 days agoSource updated Jan 22, 2025source: clinicaltrials