Clinical trial · Observational
Robotic-Assisted or Laparoscopic Radical Resection for Rectal Cancer With or Without Left Colic Artery Preservation
With or Without Left Colic Artery Preservation
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Brief Summary Background The preservation of the left colic artery (LCA) during rectal cancer resection remains a topic of controversy, and there is a notable absence of robust evidence regarding the outcomes associated with LCA preservation. And the advantages of robotic-assisted laparoscopy (RAL) surgery in rectal resection remain uncertain. The objective of this study was to assess the influence of LCA preservation surgery and RAL surgery on intraoperative and postoperative complications of rectal cancer resection. Methods Participants who underwent laparoscopic (LSC) or RAL with or without LCA preservation resection for rectal cancer between April 2020 and May 2023 were retrospectively assessed. The patients were categorized into two groups: low ligation (LL) which with preservation of LCA and high ligation (HL) which without preservation of LCA. A one-to-one propensity score-matched analysis was performed to decrease confounding. The primary outcome was operative findings, operative morbidity, and postoperative genitourinary function.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Left Colic Artery Stenosis (Diagnosis) | — | UNRESOLVED | — |
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
| Robotic Assisted Laparoscopic Surgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| with or without Left Colic Artery Preservation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- with or without Left Colic Artery Preservation
- label
- low ligation (LL) group and high ligation (HL) group
- description
- low ligation (LL) which with preservation of LCA and high ligation (HL) which without preservation of LCA
- interventionNames
- Procedure: with or without Left Colic Artery Preservation
Primary outcomes (1)
- measure
- The incidence of anastomotic leakage in postoperative patients with or without left colic artery preservation.
- timeFrame
- 2 weeks within the surgery
- description
- Within two weeks after surgery, the patient experienced abdominal pain, fever, and imaging diagnosis showed anastomotic leakage.
Secondary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Low anterior resection for rectal cancer * Postoperative pathological diagnosis of rectal adenocarcinoma * Informed consent signed prior to surgery. Exclusion Criteria: * Recurrent rectal cancer * Emergency surgery * Preoperative and intraoperative detection of distant organ metastases or extensive * Implantation metastases in the abdominal cavity * Palliative surgery * A postoperative pathology report that showed residual cancer cells at the proximal or distal resection margin * No standard chemotherapy for tumor-node-metastasis (TNM) staging II or III after surgery * Synchronous colorectal carcinoma and other organ tumors * Incomplete case data.
References
Publications (0)
Data not yet available