Subtype
Rectal Neoplasm
CI-CAN-00006564Explore in graph →
Non-malignant434 active trials1 approved drugs5 evidence items
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Subtype
CI-CAN-00006564Explore in graph →
Clinical trials
1,773 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05148767 | UGT1A1-Based Irinotecan Therapy for Locally Advanced Rectal Cancer | recruiting | Phase 4 | 606 | Zhejiang Cancer HospitalOTHER | 1 | Dec 8, 2021 | clinicaltrials |
| NCT04920435 | Prediction of the Response to Neoadjuvant Radiation Chemotherapy Through Texture Analysis Derived From Medical Imaging(RECTOMICS) | completed | — | 124 | University Hospital, BrestOTHER | 1 | Dec 7, 2021 |
| NCT01134601 | A Phase I Study of AZD6244 in Combination With Capecitabine and Radiotherapy in Locally Advanced Adenocarcinoma of the Rectum | terminated | Phase 1 | 1 | National Cancer Institute (NCI)NIH | 1 | Dec 1, 2021 | clinicaltrials |
| NCT04078828 | PR in Endoscopic LAR for Rectal Cancer | unknown | N/A | 10 | Southwest Hospital, ChinaOTHER | 1 | Nov 30, 2021 | clinicaltrials |
| NCT01308190 | Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Total Mesorectal Excision in T2-T3s N0, M0 Rectal Cancer | completed | Phase 3 | 173 | Corporacion Parc TauliOTHER | 1 | Nov 23, 2021 | clinicaltrials |
| NCT02550769 | Study of NOTES-TME Versus L-LAR in Rectal Cancer(NOTESvsL-LAR) | completed | N/A | 116 | Corporacion Parc TauliOTHER | 1 | Nov 16, 2021 | clinicaltrials |
| NCT04418895 | Neoadjuvant Therapy for Localized Rectal Adenocarcinoma | withdrawn | Phase 2 | 0 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Nov 10, 2021 | clinicaltrials |
| NCT05108753 | Short-term Outcomes of Transanal Total Mesorectal Excision With Structured Training Curriculums in China | completed | — | 175 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Nov 5, 2021 | clinicaltrials |
| NCT02319304 | Pelvic Radiotherapy With Concurrent Neoadjuvant FOLFOX for Patients With Newly Diagnosed Rectal Adenocarcinoma(GCC 1314) | terminated | Phase 2 | 3 | University of Maryland, BaltimoreOTHER | 1 | Nov 4, 2021 | clinicaltrials |
| NCT05049317 | Multicenter Study on Postoperative Urinary and Sexual Function During Laparoscopic Functional Total Mesorectum Excision | recruiting | N/A | 88 | Renmin Hospital of Wuhan UniversityOTHER | 1 | Nov 1, 2021 | clinicaltrials |
| NCT04065984 | Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES)(BiCyCLE-NMES) | unknown | N/A | 46 | London North West Healthcare NHS TrustOTHER | 1 | Oct 29, 2021 | clinicaltrials |
| NCT01987726 | Comprehensive Gene Sequencing in Guiding Treatment Recommendations Patients With Metastatic or Recurrent Solid Tumors | completed | — | 150 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Oct 28, 2021 | clinicaltrials |
| NCT04948762 | A Contemporary Review of Surgical Approaches in Pelvic Exenterative Surgery | unknown | — | 1,000 | St Vincent's University Hospital, IrelandOTHER | 1 | Oct 20, 2021 | clinicaltrials |
| NCT05079438 | Dendrobium Huoshanense Suppository in Rectal Cancer | unknown | Phase 3 | 168 | Zhejiang Cancer HospitalOTHER | 1 | Oct 15, 2021 | clinicaltrials |
| NCT05079503 | Gut Microbiome and Its Immune Modulation in Locally Advanced Rectal Cancer | unknown | N/A | 40 | Korean Cancer Study GroupOTHER | 0 | Oct 15, 2021 | clinicaltrials |
| NCT05078515 | Multicenter Validation of the PREDICT Score | completed | — | 262 | Mansoura UniversityOTHER | 1 | Oct 14, 2021 | clinicaltrials |
| NCT03699410 | Observational Study on Rectal Cancer to Verify if Response After Chemo-radiotherapy Can be Predicted With a Particular Blood Test.(LiBReCa) | terminated | — | 25 | Dimitri ChristoforidisOTHER | 1 | Oct 13, 2021 | clinicaltrials |
| NCT05076305 | PelvEx 4: Advanced Pelvic Malignancy and the Role of the Multi-disciplinary Team Meeting | unknown | — | 12 | St Vincent's University Hospital, IrelandOTHER | 1 | Oct 13, 2021 | clinicaltrials |
| NCT05068180 | Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients | unknown | Phase 4 | 200 | RenJi HospitalOTHER | 1 | Oct 6, 2021 | clinicaltrials |
| NCT03152370 | Preoperative Radiotherapy and E7046 in Rectum Cancer(PRAER 1) | completed | Phase 1 | 29 | Adlai Nortye Biopharma Co., Ltd.INDUSTRY | 3 | Oct 4, 2021 | clinicaltrials |
| NCT01899547 | Laparoscopy-Assisted Surgery for Carcinoma of the Low Rectum(LASRE) | unknown | N/A | 1,070 | Fujian Medical UniversityOTHER | 1 | Oct 1, 2021 | clinicaltrials |
| NCT02163785 | Abdominoperineal Extra-Elevators Rectal Resection for Cancer: Prone Position vs. Supine Position(APPRO) | terminated | N/A | 280 | Hospital Universitario La FeOTHER | 1 | Oct 1, 2021 | clinicaltrials |
| NCT04109755 | Neo-adjuvant Pembrolizumab and Radiotherapy in Localised MSS Rectal Cancer(PEMREC) | recruiting | Phase 2 | 25 | University Hospital, GenevaOTHER | 1 | Sep 30, 2021 | clinicaltrials |
| NCT05028192 | Mitochondria Preservation by Exercise Training: a Targeted Therapy for Cancer and Chemotherapy-induced Cachexia(MEx) | unknown | — | 144 | University of Turin, ItalyOTHER | 1 | Sep 29, 2021 | clinicaltrials |
| NCT04620473 | Anlotinib Hydrochloride Combined With Capeox in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer | withdrawn | Phase 2 | 0 | Shanghai Minimally Invasive Surgery CenterOTHER | 0 | Sep 28, 2021 | clinicaltrials |
| NCT02665026 | Effectiveness and Safety Study on Different Timing of Preventive Ileostomy Closure After Surgery for Rectal Cancer | completed | N/A | 250 | Huashan HospitalOTHER | 1 | Sep 21, 2021 | clinicaltrials |
| NCT02948348 | Study to Nivolumab Following Preoperative Chemoradiotherapy | unknown | Phase 1 / Phase 2 | 90 | Takayuki YoshinoOTHER | 1 | Sep 16, 2021 | clinicaltrials |
| NCT02746224 | Reconstruction Techniques and Vascular Approach After Laparoscopic Left Hemicolectomy and Rectum Low Anterior Resection(TAHR) | completed | N/A | 64 | Institut d'Investigació Biomèdica de Girona Dr. Josep TruetaOTHER | 1 | Sep 13, 2021 | clinicaltrials |
| NCT01458509 | Feasibility and Psychometric Properties of Paper vs. Web vs. Automated Telephone Administration of Patient Reported Outcome Surveys | completed | — | 325 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Sep 10, 2021 | clinicaltrials |
| NCT02406118 | Phase II Clinical Trial for the Evaluation of the Efficacy of Transanal TME | unknown | N/A | 49 | National Cancer Center, KoreaOTHER_GOV | 1 | Sep 10, 2021 | clinicaltrials |
| NCT02421432 | Evaluation of the Safety and the Efficacy of Transanal TME in Difficult Cases | unknown | N/A | 12 | National Cancer Center, KoreaOTHER_GOV | 1 | Sep 10, 2021 | clinicaltrials |
| NCT03280277 | Ferumoxytol-Enhanced MRI in Imaging Lymph Nodes in Patients With Locally Advanced Rectal Cancer | terminated | Early Phase 1 | 2 | OHSU Knight Cancer InstituteOTHER | 1 | Sep 10, 2021 | clinicaltrials |
| NCT03633539 | Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer(mSILSC) | withdrawn | N/A | 0 | Ruijin HospitalOTHER | 1 | Sep 10, 2021 | clinicaltrials |
| NCT02992886 | Preoperative Chemoradiotherapy With Raltitrexed for Intermediate or Locally Advanced Rectal Cancer in the Fit Elderly | completed | Phase 2 | 68 | Chinese Academy of Medical SciencesOTHER | 1 | Sep 9, 2021 | clinicaltrials |
| NCT02425059 | Irreversible Electroporation(IRE) For Unresectable Rectal Neoplasms | completed | N/A | 30 | Fuda Cancer Hospital, GuangzhouOTHER | 1 | Sep 5, 2021 | clinicaltrials |
| NCT03107650 | Preoperative Prediction Model of Pathological Outcomes (Mesorectum Quality and Positive Circumferential Resection Margin) in Patients With Mid-low Rectal Cancer(PREMARE) | completed | — | 323 | Pere Planellas GinéOTHER | 1 | Sep 5, 2021 | clinicaltrials |
| NCT04287400 | Prospective Trial for the Evaluation of Radiogenomics in Advanced Rectal Cancer | unknown | — | 210 | National Cancer Center, KoreaOTHER_GOV | 1 | Sep 5, 2021 | clinicaltrials |
| NCT05020613 | Early and Late Removal of the Urinary Catheter After Rectum Resection | unknown | N/A | 120 | Marmara UniversityOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT00040599 | Safety Study of 90Y-hMN14 to Treat Colorectal Cancer | completed | Phase 1 / Phase 2 | 72 | Gilead SciencesINDUSTRY | 5 | Aug 19, 2021 | clinicaltrials |
| NCT00041652 | Safety Study of hMN14 to Treat Either Colorectal or Breast Cancer | completed | Phase 1 / Phase 2 | 30 | Gilead SciencesINDUSTRY | 1 | Aug 19, 2021 | clinicaltrials |
| NCT01927497 | Biological Mesh Closure of the Pelvic Floor After Extralevator Abdomino Perineal Resection for Rectal Cancer(BIOPEX) | completed | Phase 3 | 104 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Aug 17, 2021 | clinicaltrials |
| NCT04267575 | Canady Helios Cold Plasma Scalpel Treatment at the Surgical Margin and Macroscopic Tumor Sites | unknown | N/A | 20 | Jerome Canady, M.D.OTHER | 1 | Aug 9, 2021 | clinicaltrials |
| NCT04455737 | Ex Vivo Intra-arterial Indigo Carmine Injection After Transanal Total Mesorectal Excision(RLF) | completed | — | 189 | Walter BrunnerOTHER | 1 | Aug 4, 2021 | clinicaltrials |
| NCT04989855 | Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune Score | unknown | Phase 2 | 48 | Sun Yat-sen UniversityOTHER | 1 | Aug 4, 2021 | clinicaltrials |
| NCT04200027 | Robotic vs. TaTME Rectal Surgery (ROTA STUDY)(ROTA) | not yet recruiting | — | 330 | Odense University HospitalOTHER | 2 | Aug 3, 2021 | clinicaltrials |
| NCT02113384 | Locally Advanced Rectal Cancer - Exfoliated Peritoneal Tumor Cells(LARC-EX) | active not recruiting | — | 231 | Oslo University HospitalOTHER | 1 | Jul 28, 2021 | clinicaltrials |
| NCT02860234 | Tailored Operative or Non-operative Management for Low-risk Rectal Cancer After Intensive Neoadjuvant Treatment | completed | — | 68 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jul 23, 2021 | clinicaltrials |
| NCT02864849 | Total Neoadjuvant Induction and Consolidation CapeOX Plus IMRT With Capecitabine for MRI Defined High-risk Rectal Cancer | completed | Phase 2 | 81 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jul 23, 2021 | clinicaltrials |
| NCT04970498 | Application of MRI in Identifying Myelosuppression Risk of Neoadjuvant Chemoradiotherapy for Rectal Cancer | unknown | — | 120 | Peking University Third HospitalOTHER | 1 | Jul 21, 2021 | clinicaltrials |
| NCT02270606 | Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer | completed | Phase 1 | 14 | Virginia Commonwealth UniversityOTHER | 1 | Jul 20, 2021 | clinicaltrials |
Data updated 24 days agoSource updated Dec 8, 2021source: clinicaltrials