Clinical trial · Observational
Locally Advanced Rectal Cancer - Exfoliated Peritoneal Tumor Cells
Prospective Observational Study of Exfoliated Peritoneal Tumor Cells in Locally Advanced Rectal Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
During the course of tumor growth and possibly by manipulation during the surgical procedure, cells from rectal tumors may be shed into the peritoneal cavity. Such cells may give rise to local recurrence or contribute to the formation of metastatic disease, specifically in the form of peritoneal carcinomatosis. Detection of cancer cells in the peritoneal cavity at the time of surgery might therefore be of value for prediction of disease recurrence with subsequent prognostic implications for these patients. In this study the investigators aim to determine the presence of exfoliated tumor cells in peritoneal lavage samples from patients undergoing surgery for LARC.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Observational study. | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Observational study
- description
- Patients with locally advanced rectum cancer undergoing surgical resection of the primary tumor at the Norwegian Radium Hospital.
- interventionNames
- Other: Observational study.
Primary outcomes (1)
- measure
- Overall survival
- timeFrame
- 5 years
- description
- Time from surgery until death from any cause
Secondary outcomes (3)
- measure
- Disease-free survival
- timeFrame
- 5 years
- description
- Time from surgery until disease recurrence or death
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * patients scheduled for surgical removal of a primary locally advanced rectal tumor at the Norwegian Radium Hospital. * age \> 18 years * written informed consent Exclusion criteria: \-
References
Publications (0)
Data not yet available