Subtype
Primary Central Nervous System Neoplasm
CI-CAN-00001432Explore in graph →
Non-malignant957 active trials5 approved drugs175 evidence items
- NCIt
- C102871
Loading cancer entity…
Subtype
CI-CAN-00001432Explore in graph →
Genomics
32 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
92 cases with simple somatic mutation data · 92 cases total · 2026-01-07 · mapped to Medulloblastoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | KMT2D |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 8 |
| 92 |
| 8.7% |
| cbioportal |
| 2 | DDX3X | Ssm | 7 | 92 | 7.6% | cbioportal |
| 4 | PTCH1 | Ssm | 6 | 92 | 6.5% | cbioportal |
| 3 | CTNNB1 | Ssm | 6 | 92 | 6.5% | cbioportal |
| 5 | ABCA13 | Ssm | 4 | 92 | 4.3% | cbioportal |
| 7 | SMARCA4 | Ssm | 4 | 92 | 4.3% | cbioportal |
| 6 | KMT2C | Ssm | 4 | 92 | 4.3% | cbioportal |
| 14 | PLXNA2 | Ssm | 3 | 92 | 3.3% | cbioportal |
| 15 | SPTB | Ssm | 3 | 92 | 3.3% | cbioportal |
| 12 | LAMA5 | Ssm | 3 | 92 | 3.3% | cbioportal |
| 8 | BCOR | Ssm | 3 | 92 | 3.3% | cbioportal |
| 10 | GPS2 | Ssm | 3 | 92 | 3.3% | cbioportal |
| 13 | MAN2C1 | Ssm | 3 | 92 | 3.3% | cbioportal |
| 16 | TP53 | Ssm | 3 | 92 | 3.3% | cbioportal |
| 9 | EPPK1 | Ssm | 3 | 92 | 3.3% | cbioportal |
| 11 | KDM6A | Ssm | 3 | 92 | 3.3% | cbioportal |
| 17 | TTN | Ssm | 3 | 92 | 3.3% | cbioportal |
| 34 | EP300 | Ssm | 2 | 92 | 2.2% | cbioportal |
| 35 | F5 | Ssm | 2 | 92 | 2.2% | cbioportal |
| 36 | FAM47B | Ssm | 2 | 92 | 2.2% | cbioportal |
| 37 | FAM53A | Ssm | 2 | 92 | 2.2% | cbioportal |
| 38 | FANCA | Ssm | 2 | 92 | 2.2% | cbioportal |
| 39 | FCGBP | Ssm | 2 | 92 | 2.2% | cbioportal |
| 40 | FGFR1 | Ssm | 2 | 92 | 2.2% | cbioportal |
| 41 | FRYL | Ssm | 2 | 92 | 2.2% | cbioportal |
| 42 | GABRG1 | Ssm | 2 | 92 | 2.2% | cbioportal |
| 43 | GALNT5 | Ssm | 2 | 92 | 2.2% | cbioportal |
| 44 | GIMAP8 | Ssm | 2 | 92 | 2.2% | cbioportal |
| 45 | GNAS | Ssm | 2 | 92 | 2.2% | cbioportal |
| 46 | GTF3C1 | Ssm | 2 | 92 | 2.2% | cbioportal |
Data updated 22 days agoSource updated 2026-01-07