Subtype
Primary Central Nervous System Neoplasm
CI-CAN-00001432Explore in graph →
Non-malignant957 active trials5 approved drugs175 evidence items
- NCIt
- C102871
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Subtype
CI-CAN-00001432Explore in graph →
Genomics
32 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
516 cases with simple somatic mutation data · 516 cases total · Data Release 46.0 · mapped to Low Grade Glioma CURATED_BROADER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | IDH1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 402 |
| 516 |
| 77.9% |
| gdc |
| 2 | NLRP5 | Ssm | 284 | 516 | 55% | gdc |
| 3 | NLRP2 | Ssm | 283 | 516 | 54.8% | gdc |
| 4 | PPP1R12C | Ssm | 282 | 516 | 54.7% | gdc |
| 6 | PEG3 | Ssm | 282 | 516 | 54.7% | gdc |
| 7 | NLRP8 | Ssm | 282 | 516 | 54.7% | gdc |
| 5 | NLRP11 | Ssm | 282 | 516 | 54.7% | gdc |
| 12 | ZNF551 | Ssm | 281 | 516 | 54.5% | gdc |
| 23 | GP6 | Ssm | 281 | 516 | 54.5% | gdc |
| 19 | ZNF470 | Ssm | 281 | 516 | 54.5% | gdc |
| 20 | ZNF667 | Ssm | 281 | 516 | 54.5% | gdc |
| 16 | ZSCAN1 | Ssm | 281 | 516 | 54.5% | gdc |
| 14 | ZNF460 | Ssm | 281 | 516 | 54.5% | gdc |
| 10 | EPS8L1 | Ssm | 281 | 516 | 54.5% | gdc |
| 18 | ZNF581 | Ssm | 281 | 516 | 54.5% | gdc |
| 8 | ZNF671 | Ssm | 281 | 516 | 54.5% | gdc |
| 9 | LILRA1 | Ssm | 281 | 516 | 54.5% | gdc |
| 22 | PTPRH | Ssm | 281 | 516 | 54.5% | gdc |
| 17 | NLRP13 | Ssm | 281 | 516 | 54.5% | gdc |
| 21 | NLRP4 | Ssm | 281 | 516 | 54.5% | gdc |
| 15 | NLRP7 | Ssm | 281 | 516 | 54.5% | gdc |
| 11 | NLRP9 | Ssm | 281 | 516 | 54.5% | gdc |
| 13 | FIZ1 | Ssm | 281 | 516 | 54.5% | gdc |
| 56 | ZNF784 | Ssm | 280 | 516 | 54.3% | gdc |
| 34 | AC020922.1 | Ssm | 280 | 516 | 54.3% | gdc |
| 48 | BRSK1 | Ssm | 280 | 516 | 54.3% | gdc |
| 30 | CCDC106 | Ssm | 280 | 516 | 54.3% | gdc |
| 37 | COX6B2 | Ssm | 280 | 516 | 54.3% | gdc |
| 29 | EPN1 | Ssm | 280 | 516 | 54.3% | gdc |
| 24 | FAM71E2 | Ssm | 280 | 516 | 54.3% | gdc |
Data updated 22 days agoSource updated Data Release 46.0