Plasma Cell Neoplasm — Genomics

Plasma Cell Neoplasm — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

2 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Multiple Myeloma (Broad, Cancer Cell 2014) mm_broadBroad

205 cases with simple somatic mutation data · 211 cases total · 2026-01-08 · mapped to Multiple Myeloma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	KRAS	Ssm	45	205	22%	cbioportal
2	NRAS	Ssm	37	205	18%	cbioportal
3	DIS3	Ssm	19	205	9.3%	cbioportal
5	ZNF717	Ssm	17	205	8.3%	cbioportal
4	TTN	Ssm	17	205	8.3%	cbioportal
6	TENT5C	Ssm	15	205	7.3%	cbioportal
7	TP53	Ssm	15	205	7.3%	cbioportal
9	MUC16

Data updated 22 days agoSource updated 2026-01-08

Multiple Myeloma CoMMpass Study MMRF-COMMPASSMMRF

961 cases with simple somatic mutation data · 995 cases total · Data Release 46.0 · mapped to Multiple Myeloma CURATED_EXACT

gdcObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	IGHV2-70

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.