Gene
CHD3
chromodomain helicase DNA binding protein 3
Explore in graph →CI-GENE-00041213HGNC:1918 ENSG00000170004 NCBI 1107 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (41)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24265153
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Skin Cutaneous Melanoma(Broad, Cancer Discov 2014) skcm_broad_brafresist_2012 | Cutaneous Melanoma | Ssm | 17 | 78 | 21.8% | 75 | cbioportal |
| Endometrial Carcinoma (TCGA GDC, 2025) ucec_tcga_gdc |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.