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CancerIndex

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Pancreatic Neuroendocrine Carcinoma · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Digestive System Neoplasm
Digestive System Neuroendocrine Neoplasm
Digestive System Neuroendocrine Carcinoma
Pancreatic Neuroendocrine Carcinoma

Subtype

Pancreatic Neuroendocrine Carcinoma

CI-CAN-00003586Explore in graph →

5 active trials1 evidence items

NCIt: C3770
OncoTree: PANEC
DOID: 1798
MeSH: D018273

Overview
Statistics
Survival
Genomics
Variants & evidence1
Drugs
Trials37
Research
Rankings
Sources & provenance

Data completeness3 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (no data yet)
Evidence (data present)
Therapies (no data yet)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

An aggressive high-grade carcinoma with neuroendocrine differentiation that arises from the pancreatic islets (islets of Langerhans). It is composed of malignant small or large cells. The mitotic count is more than 20 per 2 mm2 and/or the Ki-67 index is more than 20%.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Digestive System Neuroendocrine CarcinomaSubtype
Pancreatic CarcinomaSubtype
Pancreatic Neuroendocrine NeoplasmSubtype

Children (2)

ncit

Pancreatic Large Cell Neuroendocrine Carcinoma
Pancreatic Small Cell Neuroendocrine Carcinoma

Anatomy

Anatomical sites

Digestive SystemC3052
EndocrineC3010
PancreasC12393

Record

Identity

CancerIndex ID: CI-CAN-00003586
Entity type: Subtype
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 5
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active): 37 / 5

Publications (all / 5y)

2,596 / 112

Evidence items

1

Genes / variants

1 / 1

Drugs (any / approved)

0 / 0

Genomic cohorts

0

Epidemiology / survival obs.

0 / 0

Data updated 8 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (16)

Carcinoma, Islet Cellmesh_heading · MeSH
CARCINOMA, ISLET CELL, MALIGNANTsynonym · NCIt
High Grade Pancreatic Neuroendocrine Carcinomasynonym · NCIt
Islet Cell Cancersynonym · NCIt
Islet Cell Carcinomasynonym · NCIt
Islet Cell Tumor, Malignantsynonym · MeSH
Malignant Islet Cell Tumorsynonym · NCIt
Malignant Pancreatic Endocrine Tumorsynonym · NCIt
pancreatic endocrine cancersynonym · NCIt
Pancreatic Endocrine Carcinomasynonym · NCIt
Pancreatic NECsynonym · NCIt
Pancreatic Neuroendocrine Cancersynonym · NCIt
Pancreatic Neuroendocrine Carcinomasynonym · OncoTree
PanNECsynonym · NCIt
Poorly Differentiated Neuroendocrine Neoplasmsynonym · NCIt
Poorly Differentiated Pancreatic Endocrine Carcinomasynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths51,327countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #2 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Pancreatic Neoplasm (registry level) — open Malignant Pancreatic Neoplasm
US new cases61,467countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #10 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)figures shown for Malignant Pancreatic Neoplasm (registry level) — open Malignant Pancreatic Neoplasm
US age-standardized mortality11.3per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #2 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Pancreatic Neoplasm (registry level) — open Malignant Pancreatic Neoplasm
Active trials5countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #752 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials1countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #893 of 1,284 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items1countaccepted CIViC items · entity + descendantscivicComputedrank #392 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months14countPubMed records · stored query · 12-month windowpubmedComputedrank #855 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts0countopen GDC projects · entity + descendantsgdcComputednot in a current ranking snapshot

Data updated 8 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants