Subtype
Osteosarcoma
CI-CAN-00001321Explore in graph →
99 active trials6 approved drugs5 evidence items
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Subtype
CI-CAN-00001321Explore in graph →
Clinical trials
349 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (40)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03013127 | A Study of Pembrolizumab in Patients With Relapsed Or Metastatic Osteosarcoma Not Eligible for Curative Surgery(PROMO) | terminated | Phase 2 | 12 | Oslo University HospitalOTHER | 2 | Oct 14, 2020 | clinicaltrials |
| NCT01987102 | Investigation of [6R] 5,10-methylenetetrahydrofolate (Arfolitixorin) as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX. | completed | Phase 1 / Phase 2 | 18 | Isofol Medical ABINDUSTRY | 4 | Sep 25, 2020 |
| clinicaltrials |
| NCT02097238 | Eribulin Mesylate in Treating Patients With Recurrent or Refractory Osteosarcoma | completed | Phase 2 | 19 | National Cancer Institute (NCI)NIH | 2 | May 19, 2020 | clinicaltrials |
| NCT04351308 | Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade Osteosarcoma(MAPAC) | unknown | Phase 2 | 60 | Peking University People's HospitalOTHER | 1 | May 19, 2020 | clinicaltrials |
| NCT01154816 | Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia | completed | Phase 2 | 118 | Children's Oncology GroupNETWORK | 2 | May 13, 2020 | clinicaltrials |
| NCT04319874 | Phase II Clinical Trial Scheme of Ganoderma Lucidum Spore Powder for Postoperative Chemotherapy of Osteosarcoma | unknown | Phase 2 | 80 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Mar 30, 2020 | clinicaltrials |
| NCT01848457 | Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy | completed | Phase 2 | 13 | Children's Hospital of PhiladelphiaOTHER | 1 | Mar 16, 2020 | clinicaltrials |
| NCT04294511 | Study of Camrelizumab in Combination With Neoadjuvant Chemotherapy in the Treatment of Osteosarcoma | unknown | Phase 2 | 75 | Sun Yat-sen UniversityOTHER | 1 | Mar 4, 2020 | clinicaltrials |
| NCT00752206 | A Placebo-Controlled Study of Saracatinib (AZD0530) in Patients With Recurrent Osteosarcoma Localized to the Lung | terminated | Phase 2 | 38 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | Jan 18, 2020 | clinicaltrials |
| NCT01005043 | Therapy Trial to Determine the Safety and Efficacy of Heavy Ion Radiotherapy in Patients With Osteosarcoma | completed | Phase 1 / Phase 2 | 23 | University Hospital HeidelbergOTHER | 1 | Jan 10, 2020 | clinicaltrials |
| NCT01962103 | Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors | completed | Phase 1 / Phase 2 | 107 | CelgeneINDUSTRY | 7 | Dec 27, 2019 | clinicaltrials |
| NCT02856048 | Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancer(PRESOV) | unknown | Phase 2 / Phase 3 | 11 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Dec 17, 2019 | clinicaltrials |
| NCT01886105 | Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma | terminated | Phase 2 | 4 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Oct 29, 2019 | clinicaltrials |
| NCT02441309 | A Eurosarc Study of Mifamurtide in Advanced Osteosarcoma (MEMOS)(MEMOS) | terminated | Phase 2 | 8 | University of OxfordOTHER | 5 | Sep 13, 2019 | clinicaltrials |
| NCT02689336 | Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors | withdrawn | Phase 2 | 0 | Washington University School of MedicineOTHER | 0 | Sep 9, 2019 | clinicaltrials |
| NCT01650090 | Phase 2 Study of Inhaled Lipid Cisplatin in Pulmonary Recurrent Osteosarcoma | completed | Phase 2 | 28 | Eleison Pharmaceuticals LLC.INDUSTRY | 1 | Aug 7, 2019 | clinicaltrials |
| NCT00978471 | Adjuvant High-Dose Thiotepa and Stem Cell Rescue Associated With Conventional Chemotherapy in Relapsed Osteosarcoma(OSII-TTP) | completed | Phase 2 | 44 | Centre Leon BerardOTHER | 1 | May 17, 2019 | clinicaltrials |
| NCT02718482 | Phase II Trial for the Treatment of Relapsed Osteosarcoma(OsteoREC2015) | terminated | Phase 2 | 7 | Italian Sarcoma GroupNETWORK | 1 | May 13, 2019 | clinicaltrials |
| NCT01614795 | Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma | completed | Phase 2 | 46 | National Cancer Institute (NCI)NIH | 2 | Dec 11, 2018 | clinicaltrials |
| NCT00038207 | Liposomal Vincristine for Pediatric and Adolescent Patients With Relapsed Malignancies | completed | Phase 2 | 29 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 31, 2018 | clinicaltrials |
| NCT03676985 | A Clinical Study of PD-L1 Antibody ZKAB001(Drug Code) in Limited Stage of High-grade Osteosarcoma | unknown | Phase 1 / Phase 2 | 15 | Lee's Pharmaceutical LimitedINDUSTRY | 1 | Sep 26, 2018 | clinicaltrials |
| NCT01986829 | Cryoablation, Radiofrequency Ablation, or Microwave Ablation in Treating Patients With Metastatic Sarcoma Stable on Chemotherapy | terminated | Phase 2 | 9 | Washington University School of MedicineOTHER | 1 | Sep 19, 2018 | clinicaltrials |
| NCT01807468 | Haploidentical Stem Cell Transplantation and NK Cell Therapy in Patients With High-risk Solid Tumors | unknown | Phase 2 | 12 | Samsung Medical CenterOTHER | 1 | Sep 18, 2018 | clinicaltrials |
| NCT00617890 | A Study to Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720) | terminated | Phase 2 | 219 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Aug 23, 2018 | clinicaltrials |
| NCT01154452 | Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma | completed | Phase 1 / Phase 2 | 78 | National Cancer Institute (NCI)NIH | 1 | Aug 15, 2018 | clinicaltrials |
| NCT02011126 | Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors | withdrawn | Phase 2 | 0 | Children's Oncology GroupNETWORK | 0 | Aug 7, 2018 | clinicaltrials |
| NCT01553539 | Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery | completed | Phase 2 | 20 | Wake Forest University Health SciencesOTHER | 1 | Jul 5, 2018 | clinicaltrials |
| NCT02711007 | Apatinib for Advanced Osteosarcoma After Failure of Standard Multimodal Therapy | completed | Phase 2 / Phase 3 | 37 | GUO WEIOTHER | 1 | Apr 23, 2018 | clinicaltrials |
| NCT03390946 | Feasibility Study of Interval Compressed Regimen Using Four-drugs for Osteosarcoma | unknown | Phase 2 | 23 | Byung-Kiu ParkOTHER_GOV | 1 | Jan 9, 2018 | clinicaltrials |
| NCT02982486 | A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma | unknown | Phase 2 | 60 | Assaf-Harofeh Medical CenterOTHER_GOV | 0 | Nov 1, 2017 | clinicaltrials |
| NCT00102531 | Inhalation SLIT Cisplatin (Liposomal) for the Treatment of Osteosarcoma Metastatic to the Lung | completed | Phase 1 / Phase 2 | 19 | Insmed IncorporatedINDUSTRY | 1 | Aug 1, 2017 | clinicaltrials |
| NCT00112463 | Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma | completed | Phase 2 | 40 | National Cancer Institute (NCI)NIH | 0 | Jun 14, 2017 | clinicaltrials |
| NCT03163381 | Apatinib Second Line Treatment for Advanced Osteosarcoma and Soft Tissue Sarcomas ,Openting ,Single Center, One-armed Clinical Study. | unknown | Phase 2 | 40 | Henan Cancer HospitalOTHER_GOV | 1 | May 23, 2017 | clinicaltrials |
| NCT03063983 | Clinical Trial Evaluating Metronomic Chemotherapy in Patients With Metastatic Osteosarcoma(GLATO2017) | unknown | Phase 2 | 158 | Grupo de Apoio ao Adolescente e a Crianca com CancerOTHER | 1 | Mar 13, 2017 | clinicaltrials |
| NCT00586846 | Phase II Study of Chemotherapy and Pamidronate for the Treatment of Newly Diagnosed Osteosarcoma | completed | Phase 2 | 40 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jan 20, 2016 | clinicaltrials |
| NCT00743509 | A Phase II Study of Oral Cyclophosphamide and Sirolimus (OCR) in Advanced Sarcoma(OCR) | completed | Phase 2 | 49 | University of Michigan Rogel Cancer CenterOTHER | 1 | Sep 28, 2015 | clinicaltrials |
| NCT01016015 | Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma | completed | Phase 2 | 178 | National Cancer Institute (NCI)NIH | 2 | Jul 30, 2015 | clinicaltrials |
| NCT01804374 | Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma(SERIO) | completed | Phase 2 | 38 | Italian Sarcoma GroupNETWORK | 1 | Jun 17, 2015 | clinicaltrials |
| NCT02022358 | Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays? | terminated | Phase 2 | 34 | University College, LondonOTHER | 1 | Jun 4, 2015 | clinicaltrials |
| NCT02429973 | Trial With Gemcitabine and Rapamycin in Second Line of Metastatic Osteosarcoma(GEIS-29) | completed | Phase 2 | 33 | Broto, Javier Martín, M.D.INDIV | 0 | Apr 29, 2015 | clinicaltrials |
| NCT00030667 | Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood | completed | Phase 2 | 100 | National Cancer Institute (NCI)NIH | 1 | Apr 15, 2015 | clinicaltrials |
| NCT00831844 | Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors | completed | Phase 2 | 116 | National Cancer Institute (NCI)NIH | 3 | Mar 30, 2015 | clinicaltrials |
| NCT00093080 | Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED) | completed | Phase 2 | 216 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Feb 13, 2015 | clinicaltrials |
| NCT00331643 | Ixabepilone in Treating Young Patients With Refractory Solid Tumors | completed | Phase 2 | 120 | National Cancer Institute (NCI)NIH | 1 | Nov 14, 2014 | clinicaltrials |
| NCT00503295 | Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung | completed | Phase 2 | 53 | Oncolytics BiotechINDUSTRY | 1 | Oct 2, 2014 | clinicaltrials |
| NCT00634322 | High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma | terminated | Phase 2 | 7 | BTG International Inc.OTHER | 0 | Sep 15, 2014 | clinicaltrials |
| NCT01002092 | A Study of Endostar Combined With Chemotherapy for Treatment of Osteosarcoma | unknown | Phase 2 | 160 | Shandong Simcere-Medgenn Bio-pharmaceutical Co., LtdINDUSTRY | 1 | Sep 3, 2014 | clinicaltrials |
| NCT00330421 | Sorafenib in Treating Patients With Soft Tissue Sarcomas (Extremity Sarcoma Closed to Entry as of 5/30/07) | completed | Phase 2 | 15 | National Cancer Institute (NCI)NIH | 1 | Apr 30, 2014 | clinicaltrials |
| NCT01216826 | Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Osteosarcoma | unknown | Phase 2 | 20 | Sidnei EpelmanOTHER | 1 | Aug 7, 2013 | clinicaltrials |
| NCT00004078 | Irinotecan in Treating Children With Refractory Solid Tumors | completed | Phase 2 | 181 | Children's Oncology GroupNETWORK | 1 | Jun 14, 2013 | clinicaltrials |
Data updated 22 days agoSource updated Oct 14, 2020source: clinicaltrials